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Current approaches to antithrombotic therapy in patients with cardioembolic stroke

https://doi.org/10.14412/2074-2711-2013-2356

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Abstract

The rate of cardiogenic embolism among all ischemic strokes is as high as 38%. Cardioembolic strokes are characterized by the higher magnitude of neurological deficit, the high risk of recurrent acute stroke, and a lethal outcome. This review deals with the etiopathogenesis of thrombus formation in the heart chambers, with current criteria for the verification of cardioembolic strokes, with the results of trials of new oral anticoagulants, and latest guidelines for antithrombotic therapy to prevent stroke. Special focus is given to secondary stroke prevention in patients with nonvalvular atrial fibrillation since it is atrial fibrillation that is the most common cause of cardioembolic stroke.

About the Authors

Oleg Ivanovich Vinogradov
N.I. Pirogov National Medical Surgical Center, Moscow
Russian Federation


A N Kuznetsov
N.I. Pirogov National Medical Surgical Center, Moscow
Russian Federation


N V Rybalko
N.I. Pirogov National Medical Surgical Center, Moscow
Russian Federation


References

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For citation:


Vinogradov O.I., Kuznetsov A.N., Rybalko N.V. Current approaches to antithrombotic therapy in patients with cardioembolic stroke. Neurology, Neuropsychiatry, Psychosomatics. 2013;5(2S):28-39. (In Russ.) https://doi.org/10.14412/2074-2711-2013-2356

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