Biological basis of aggressive behavior
Abstract
This scientific review highlights the results of domestic and foreign studies aimed at researching the biological aspects of failure to control aggressive impulses. We analyze the role of serotonergic, dopaminergic, noradrenergic, glutamatergic systems, and neuroendocrine mechanisms in aggression manifestation. We discuss the inconsistency of modern concepts about the neurochemical nature of aggressive behavior. The relevance of evaluating the biomarkers of public danger is substantiated. Finally, questions of psychopharmacotherapy of aggressive behavior are reviewed.
About the Authors
O. A. Makushkina
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation
Russian Federation
23, Kropotkinskiy per., Moscow 119034
O. I. Gurina
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation
Russian Federation
23, Kropotkinskiy per., Moscow 119034
V. A. Golenkova
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation
Russian Federation
23, Kropotkinskiy per., Moscow 119034
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Review
For citations:
Makushkina O.A., Gurina O.I., Golenkova V.A. Biological basis of aggressive behavior. Neurology, Neuropsychiatry, Psychosomatics. 2022;14(1):76-81. (In Russ.) https://doi.org/10.14412/2074-2711-2022-1-76-81
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