On the neurological roles of chondroitin sulfate and glucosamine sulfate: a systematic analysis
https://doi.org/10.14412/2074-2711-2019-3-137-143
Abstract
Chondroitin sulfate (CS) and glucosamine sulfate (GS) are widely used as chondroprotectors. Data mining of 42,051 publications on the effects of CS/GS showed that impairments in the their metabolism were characteristic of ischemic, neurodegenerative diseases, convulsive disorders or conditions, and neuropsychological diseases (schizophrenia, affective disorders). The results of experimental studies indicate that it is expedient to use CS and GS in the therapy of ischemic and neurodegenerative diseases.
About the Authors
O. A. Gromova
Federal Research Center «Informatics and Management», Russian Academy of Sciences;
M.V. Lomonosov Moscow State University
Russian Federation
Russian Federation
44, Vavilov St., Build. 2, Moscow 119333;
Big Data Storage and Analysis Center, 1, Leninskie Gory, Moscow 119234
I. Yu. Torshin
Federal Research Center «Informatics and Management», Russian Academy of Sciences;
M.V. Lomonosov Moscow State University
Russian Federation
Russian Federation
44, Vavilov St., Build. 2, Moscow 119333;
Big Data Storage and Analysis Center, 1, Leninskie Gory, Moscow 119234
V. A. Semenov
M.V. Lomonosov Moscow State University
State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Big Data Storage and Analysis Center, 1, Leninskie Gory, Moscow 119234;
22a, Voroshilov St., Kemerovo 650056
L. I. Stakhovskaya
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Research Institute of Cerebrovascular Disease and Stroke, 1, Ostrovityanov St., Moscow 117997
Russian Federation
Research Institute of Cerebrovascular Disease and Stroke, 1, Ostrovityanov St., Moscow 117997
K. V. Rudakov
Federal Research Center «Informatics and Management», Russian Academy of Sciences;
M.V. Lomonosov Moscow State University
Russian Federation
Russian Federation
44, Vavilov St., Build. 2, Moscow 119333;
Big Data Storage and Analysis Center, 1, Leninskie Gory, Moscow 119234
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For citations:
Gromova OA, Torshin IY, Semenov VA, Stakhovskaya LI, Rudakov KV. On the neurological roles of chondroitin sulfate and glucosamine sulfate: a systematic analysis. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2019;11(3):137-143. (In Russ.) https://doi.org/10.14412/2074-2711-2019-3-137-143
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