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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2011-4-</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-99</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Mechanisms in the pathogenesis of poststroke spasticity</article-title><trans-title-group xml:lang="ru"><trans-title>Механизмы патогенеза постинсультной спастичности</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катушкина</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Katushkina</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">elina_katushkina@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиновьева</surname><given-names>О. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinovyeva</surname><given-names>O. E.</given-names></name></name-alternatives><email xlink:type="simple">info@ima-press.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шенкман</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shenkman</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@ima-press.net</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яхно</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakhno</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">info@ima-press.net</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый МГМУ им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГНЦ РФ Институт медико-биологических проблем РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Biomedical Problems, Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>14</day><month>12</month><year>2011</year></pub-date><volume>3</volume><issue>4</issue><issue-title>NO4 (2011)</issue-title><fpage>14</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Katushkina E.A., Zinovyeva O.E., Shenkman B.S., Yakhno N.N., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Катушкина Э.А., Зиновьева О.Е., Шенкман Б.С., Яхно Н.Н.</copyright-holder><copyright-holder xml:lang="en">Katushkina E.A., Zinovyeva O.E., Shenkman B.S., Yakhno N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/99">https://nnp.ima-press.net/nnp/article/view/99</self-uri><abstract/><trans-abstract xml:lang="ru"/><kwd-group xml:lang="ru"><kwd>постинсультная церебральная спастичность</kwd><kwd>пирамидный тракт</kwd><kwd>сегментарный аппарат спинного мозга</kwd><kwd>изменения мышц</kwd><kwd>миозин</kwd><kwd>капилляризация мыщцы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>poststroke cerebral spasticity</kwd><kwd>pyramidal tract</kwd><kwd>segmental apparatus of the spinal cord</kwd><kwd>muscle changes</kwd><kwd>myosin</kwd><kwd>muscle capillarization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Ковражкина Е.А. 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Postvibration depression of the H-reflex as a result of a dual mechanism: an experimental study in humans. J Clin Neurophysiol 2001;18(5):460–70.&lt;/p&gt;&lt;p&gt;Pontеn E.M., Stаl P.S. Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis. J Neurol Scien 2007;253:25–33.&lt;/p&gt;&lt;p&gt;Lieber R.L., Runesson E., Einarsson F. et al. Inferior mechanical properties of a spastic muscle bundles due to hypertrophic but compromised extracellular matrix material. Muscle Nerve 2003;28:464–71.&lt;/p&gt;&lt;p&gt;Lukacs M. F wave measurements detecting changes in motor neuron excitability after ischaemic stroke. Electromyogr Clin Neurophysiol 2007;47(2):109–15.&lt;/p&gt;&lt;p&gt;Matsumoto S., Kawahira K., Etoh S. еt al. Short-term effects of thermotherapy for spasticity on tibial nerve F-waves in post-stroke patients. Int J Biometeorol 2006;50(4):243–50.&lt;/p&gt;&lt;p&gt;Milanov I. 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Morphological and functional brain alterations. Brain 1996;119:1849–57.&lt;/p&gt;&lt;p&gt;Watkin C.L., Leathley M.J., Gregson J.M. et al. Prevalence of spasticity post stroke. Clin Rehabil 2002;16:515–22.&lt;/p&gt;&lt;p&gt;Завалишин И.А., Бархатова В.П. Спастичность. Журн неврол и психиатр 1997;97(3):68–70.&lt;/p&gt;&lt;p&gt;Lamy J.C., Wargon I., Mazevet D. et al. Impaired efficacy of spinal presynaptic mechanisms in spastic stroke patients. Brain 2009;132:734–48.&lt;/p&gt;&lt;p&gt;Huang C.Y., Wang C.H., Hwang I.S. Characterization of the mechanical and neural components of spastic hypertonia with modified H reflex. J Electromyogr Kinesiol 2006;16(4):384–91.&lt;/p&gt;&lt;p&gt;Booth C.M., Cortina-Borja M.J.F., Theologis T.N. Collagen accumulation in muscles of сhildren with cerebral palsy and correlation with severity of spasticity. Developmental Med Child Neurol 2001;43:314–20.&lt;/p&gt;&lt;p&gt;Ito J., Araki A., Tanaka H. et al. Muscle histopathology in spastic cerebral palsy. Brain Development 1996;18:299–303.&lt;/p&gt;&lt;p&gt;Scelsi R., Lotta S., Lommi G. et al. Hemiplegic atrophy. Morphological findings in the anterior tibial muscle of patients with cerebral vascular accidents. Acta Neuropathol (Berl) 1984;62(4):324–31.&lt;/p&gt;&lt;p&gt;Abbruzzese M., Minatel C., Reni L. et al. Postvibration depression of the H-reflex as a result of a dual mechanism: an experimental study in humans. J Clin Neurophysiol 2001;18(5):460–70.&lt;/p&gt;&lt;p&gt;Pontеn E.M., Stаl P.S. Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis. J Neurol Scien 2007;253:25–33.&lt;/p&gt;&lt;p&gt;Lieber R.L., Runesson E., Einarsson F. et al. Inferior mechanical properties of a spastic muscle bundles due to hypertrophic but compromised extracellular matrix material. Muscle Nerve 2003;28:464–71.&lt;/p&gt;&lt;p&gt;Lukacs M. F wave measurements detecting changes in motor neuron excitability after ischaemic stroke. Electromyogr Clin Neurophysiol 2007;47(2):109–15.&lt;/p&gt;&lt;p&gt;Matsumoto S., Kawahira K., Etoh S. еt al. Short-term effects of thermotherapy for spasticity on tibial nerve F-waves in post-stroke patients. Int J Biometeorol 2006;50(4):243–50.&lt;/p&gt;&lt;p&gt;Milanov I. Clinical and neurophysiological correlations of spasticity. Funct Neurol 1999;14(4):193–201.&lt;/p&gt;&lt;p&gt;Pette D., Staron R.S. Transitions of muscle fiber phenotypic profiles. Histochem Cell Biol 2001;115(5):359–72.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
