nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2017-4-70-76nnp-800Research ArticleREVIEWSОБЗОРЫHypertension and cognitive impairment: the standpoint of evidence-based medicineАртериальная гипертензия и когнитивные нарушения: взгляд с позиций доказательной медициныОстроумоваТ. М.OstroumovaT. M.

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Moscow 119021

ПарфеновВ. А.ParfenovV. A.

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Moscow 119021

ОстроумоваО. Д.OstroumovaO. D.

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11

127423, Москва, ул. Делегатская, 20/1

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Moscow 119021

20/1, Delegatskaya St., Moscow 127423

ostroumova.olga@mail.ruФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский университет) Минздрава РоссииРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian FederationФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский университет) Минздрава России ФГБОУ ВО «Московский государственный медико- стоматологический университет им. А.И. Евдокимова» Минздрава РоссииРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaRussian Federation201714122017947076Copyright © Ostroumova T.M., Parfenov V.A., Ostroumova O.D., 20172017Остроумова Т.М., Парфенов В.А., Остроумова О.Д.Ostroumova T.M., Parfenov V.A., Ostroumova O.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/800

Hypertension is one of the main modifiable risk factors for cognitive impairment (CI) and dementia in middle-aged and elderly patients. CI occurs in patients with hypertension even with its short duration and is manifested by controlling dysfunctiona and cognitive speed decline. The paper presents the results of a neuropsychological examination in 50 patients of middle age (47.54±5.2 years) with short-term (2.6±5.5 years) and uncomplicated hypertension. Stable blood pressure normalization during antihypertensive therapy improves cognitive function and prevents the progression of CI and the development of dementia. The use of nicergoline in patients with hypertension and CI is  discussed.

Артериальная гипертензия (АГ) является одним из главных корригируемых факторов риска развития когнитивных нарушений (КН) и деменции у пациентов среднего и пожилого возраста. КН возникают даже при небольшой длительности заболевания и проявляются расстройствами управляющих функций, снижением скорости когнитивных процессов. Представлены результаты нейропсихологического обследования 50 пациентов среднего возраста (47,54±5,2 года) с недлительной (2,6±5,5 года) и неосложненной АГ. Стойкая нормализация артериального давления на фоне антигипертензивной терапии улучшает когнитивные функции, предупреждает прогрессирование КН и развитие деменции. Обсуждается применение ницерголина у пациентов с АГ и КН.

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The authors declare that there are no conflicts of interest present.