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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2017-4-38-45</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-794</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>In-hospital stroke in patients after cardiac surgery or invasive interventions</article-title><trans-title-group xml:lang="ru"><trans-title>Внутрибольничный инсульт у пациентов после кардиохирургических операций и инвазивных вмешательств на сердце</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филимонова</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Filimonova</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней, нейрохирургии и медицинской генетики</p><p>620028, Екатеринбург, ул. Репина, 3</p><p>620192, Екатеринбург, ул. Волгоградская, 185</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases, Neurosurgery, and Medical Genetics</p><p>3, Repin St., Yekaterinburg 620028</p><p>185, Volgogradskaya St., Yekaterinburg 620192</p></bio><email xlink:type="simple">polinafilimonova@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волкова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkova</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней, нейрохирургии и медицинской генетики</p><p>620028, Екатеринбург, ул. Репина, 3</p><p>620192, Екатеринбург, ул. Волгоградская, 185</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases, Neurosurgery, and Medical Genetics</p><p>3, Repin St., Yekaterinburg 620028</p><p>185, Volgogradskaya St., Yekaterinburg 620192</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алашеев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alasheev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>620192, Екатеринбург, ул. Волгоградская, 185</p></bio><bio xml:lang="en"><p>185, Volgogradskaya St., Yekaterinburg 620192</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhaylov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>620192, Екатеринбург, ул. Волгоградская, 185</p></bio><bio xml:lang="en"><p>185, Volgogradskaya St., Yekaterinburg 620192</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гричук</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grichuk</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>620192, Екатеринбург, ул. Волгоградская, 185</p></bio><bio xml:lang="en"><p>185, Volgogradskaya St., Yekaterinburg 620192</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ВО «Уральский государственный медицинский университет» Минздрава России&#13;
&#13;
ГБУЗ Свердловской области «Свердловская областная клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University, Ministry of Health of Russia&#13;
&#13;
Sverdlovsk Regional Clinical Hospital One</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ Свердловской области «Свердловская областная клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sverdlovsk Regional Clinical Hospital One</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2017</year></pub-date><volume>9</volume><issue>4</issue><fpage>38</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Filimonova P.A., Volkova L.I., Alasheev A.M., Mikhaylov A.V., Grichuk E.A., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Филимонова П.А., Волкова Л.И., Алашеев А.М., Михайлов А.В., Гричук Е.А.</copyright-holder><copyright-holder xml:lang="en">Filimonova P.A., Volkova L.I., Alasheev A.M., Mikhaylov A.V., Grichuk E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/794">https://nnp.ima-press.net/nnp/article/view/794</self-uri><abstract><p>Most in-hospital strokes occur after cardiac or vascular surgeries, during invasive therapeutic and diagnostic procedures on the heart and blood vessels. The incidence of stroke after coronary artery bypass grafting is about 2%; that after valve surgery and percutaneous cardiac intervention is 1 to 10% and 0.03 to 0.4%, respectively.</p><sec><title>Objective</title><p>Objective: to analyze the risk factors, pathogenetic, clinical, and laboratory characteristics of stroke after cardiac surgery and invasive interventions.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. The investigation enrolled in-hospital stroke patients who had undergone invasive cardiac or open-heart surgery in Sverdlovsk Regional Hospital One in 2011 to 2015. A comparison group consisted of 196 patients with community-acquired stroke.</p></sec><sec><title>Results</title><p>Results. Stroke after cardiac surgical or endovascular interventions developed in 88 patients (44.9% of all the in-hospital stroke cases registered in the above period). The incidence of stroke after open-heart surgery was 0.97% (63 cases), depending on the type of surgery. Stroke following open-heart surgery was recorded after combined correction (1.4%), two-valve replacement surgery (1.98%), aortic and mammary coronary artery bypass grafting under extracorporeal circulation (1%), and beating heart bypass surgery (0.25%). The severity of stroke and the degree of disability did not differ in patients after invasive cardiac and open-heart surgeries.</p></sec><sec><title>Conclusion</title><p>Conclusion. Patients who have undergone cardiac surgery and are at high risk for in-hospital stroke should be followed up and should receive preventive treatment for stroke in the early postoperative period.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Большинство внутрибольничных инсультов возникает после кардиохирургических или сосудистых операций, при инвазивных лечебных и диагностических манипуляциях на  сердце и сосудах. Частота инсультов после шунтирующих операций на сердце составляет  около 2%, после операций на клапанах сердца – от 1 до 10%, после перкутанных операций на сердце – от 0,03 до 0,4%.</p><p>Цель исследования – анализ факторов риска, патогенетических и клинико-лабораторных особенностей острых нарушений мозгового кровообращения (ОНМК) после кардиохирургических операций и инвазивных вмешательств на сердце.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. В исследование включены пациенты с внутрибольничным ОНМК, которые перенесли инвазивное вмешательство или открытую операцию на сердце с 2011 по 2015 г. на базе Свердловской областной клинической больницы № 1. В группу сравнения вошли 196 пациентов с внебольничным ОНМК.</p></sec><sec><title>Результаты</title><p>Результаты. У 88 пациентов развилось ОНМК после хирургического или инвазивного вмешательства на сердце, это 44,9% всех зарегистрированных за указанный период внутрибольничных ОНМК. Частота ОНМК у пациентов после открытых операций на сердце составила 0,97% (63 наблюдения) и зависела от типа вмешательства. ОНМК после открытых операций на сердце у 1,4% пациентов зарегистрированы после сочетанных коррекций, у 1,98% – после двуклапанных, у 1% – после аорто- и маммарокоронарного шунтирования (в случае использования аппарата искусственного кровообращения) и у 0,25 % – после шунтирующих операций на работающем сердце. Тяжесть инсульта и степень инвалидизации пациентов не отличались при инвазивных вмешательствах и открытых операциях на сердце.</p></sec><sec><title>Заключение</title><p>Заключение. Пациенты, перенесшие кардиохирургические вмешательства и имеющие высокий риск внутрибольничных ОНМК, должны находиться под наблюдением, в том числе получать профилактическое лечение ОНМК в раннем послеоперационном периоде.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>внутрибольничный инсульт</kwd><kwd>кардиохирургические вмешательства</kwd><kwd>инвазивные вмешательства на сердце</kwd><kwd>факторы риска инсульта</kwd></kwd-group><kwd-group xml:lang="en"><kwd>in-hospital stroke</kwd><kwd>cardiac surgery</kwd><kwd>invasive cardiac surgery</kwd><kwd>risk factors for stroke</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Selim M. Perioperative stroke. N Engl J Med. 2007 Feb 15;356(7):706-13. doi: 10.1056/NEJMra062668</mixed-citation><mixed-citation xml:lang="en">Selim M. Perioperative stroke. 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