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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2017-3-42-47</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-771</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Screening for non-motor symptoms in Parkinson's disease using the NMSQuest scale</article-title><trans-title-group xml:lang="ru"><trans-title>Скрининг немоторных симптомов болезни Паркинсона с помощью шкалы NMSQuest</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таппахов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tappakhov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>677000, Россия, Якутск, ул. Белинского, 58;</p></bio><bio xml:lang="en"><p>58, Belinsky St., Yakutsk, 677000, Russia;</p></bio><email xlink:type="simple">dralex89@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>677000, Россия, Якутск, ул. Белинского, 58;</p></bio><bio xml:lang="en"><p>58, Belinsky St., Yakutsk, 677000, Russia;</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Т. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>T. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>677000, Россия, Якутск, ул. Белинского, 58;</p></bio><bio xml:lang="en"><p>58, Belinsky St., Yakutsk, 677000, Russia;</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шнайдер</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Schnaider</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>660022, Россия, Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>1, Partisan Zheleznyak St., Krasnoyarsk 660022, Russia</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>660022, Россия, Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>1, Partisan Zheleznyak St., Krasnoyarsk 660022, Russia</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Северо-Восточный федеральный университет им. М.К. Аммосова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov North-Eastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>11</month><year>2017</year></pub-date><volume>9</volume><issue>3</issue><fpage>42</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Tappakhov A.A., Popova T.E., Nikolaeva T.Y., Schnaider N.A., Petrova M.M., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Таппахов А.А., Попова Т.Е., Николаева Т.Я., Шнайдер Н.А., Петрова М.М.</copyright-holder><copyright-holder xml:lang="en">Tappakhov A.A., Popova T.E., Nikolaeva T.Y., Schnaider N.A., Petrova M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/771">https://nnp.ima-press.net/nnp/article/view/771</self-uri><abstract><p>The clinical picture of Parkinson's disease (PD) includes a wide range of non-motor symptoms (NMS) that substantially worsen quality of life in patients. These symptoms are poorly diagnosed because they are not emphasized by patients themselves and their relatives. The low detectability of NMS can be attributable to the lack of awareness amongst specialists about a wide range of PD symptoms and to that of time at a visit for physician advice.Objective: to evaluate the effectiveness of using the screening scale to timely detect NMS in PD.Patients and methods. Examinations were made in 2 patient groups: 1) 95 PD patients aged 47 to 83 years (mean age, 64.91±7.66 years) (a study group); 2) 37 sex- and age-matched healthy individuals aged 48 to 77 years (mean age, 62.22±6.58 years) without signs of PD and PD of another etiology (a control group). To identify NMS, all the study participants filled out the NMSQuest scale.Results. The mean number of NMS per patient with PD was 9.13±4.81 in the study group and 5.43±3.4 in the control group (p&lt;0.001).Symptoms, such as hypersalivation, hyposmia, dysphagia, nausea, vomiting, constipation, excessive sweating, decreased motivation, and a feeling of sadness, were statistically significantly more common in PD. There were no significant differences between the number of NMSs and the form of PD or convincing data on their relationship to age, disease stage, and the total equivalent dose of taken antiparkinsonian drugs (calculated with reference to levodopa).Conclusion. The use of questionnaires in patients with PD allows the timely detection of the majority of NMSs. Given the limited time for counseling the patient, especially at an outpatient stage, the questionnaires should be filled out by the patient while he/she is waiting for a doctor's consultation.</p></abstract><trans-abstract xml:lang="ru"><p>Клиническая картина болезни Паркинсона (БП) включает широкий спектр немоторных симптомов (НМС), которые значительно ухудшают качество жизни пациентов. Эти симптомы плохо диагностируются, поскольку сами пациенты и их родственники не придают им значения. Низкая выявляемость НМС может объясняться недостаточной осведомленностью специалистов о широком спектре симптомов БП, а также дефицитом времени на консультативном приеме.Цель исследования – оценить эффективность использования скрининговой шкалы для своевременного выявления НМС БП.Пациенты и методы. Обследовано две группы пациентов: 1-ю (основную) группу составили 95 пациентов с БП в возрасте от 47 до 83 лет (средний возраст – 64,91±7,66 года), 2-ю (контрольную) группу – 37 лиц в возрасте от 48 до 77 лет (средний возраст – 62,22±6,58 года) без признаков БП и паркинсонизма другой этиологии, сопоставимые с пациентами основной группы по полу и возрасту. Все участники исследования заполняли шкалу для выявления НМС (NMSQuest).Результаты. Среднее число НМС на 1 пациента с БП составило 9,13±4,81 против 5,43±3,4 у лиц контрольной группы (p&lt;0,001).Такие симптомы, как гиперсаливация, гипосмия, дисфагия, тошнота, рвота, запор, повышенная потливость, снижение мотивации и чувство грусти, при БП встречались статистически значимо чаще. Не получено достоверных различий между количеством НМС и формой болезни, а также убедительных данных об их связи с возрастом, стадией заболевания и суммарной эквивалентной дозой принимаемых противопаркинсонических препаратов (в пересчете на леводопу).Заключение. Использование шкал-опросников у пациентов с БП позволяет своевременно выявить большинство НМС. Учитывая ограниченное время на консультирование пациента, особенно на амбулаторном этапе, рекомендуем их заполнение во время ожидания приема врача.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Паркинсона</kwd><kwd>немоторные проявления</kwd><kwd>диагностика</kwd><kwd>шкалы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Parkinson's disease</kwd><kwd>non-motor symptoms</kwd><kwd>diagnosis</kwd><kwd>scales</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aron L, Klein R. 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