nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2017-2-65-70nnp-749Research ArticleREVIEWSОБЗОРЫCognitive and non-cognitive neuropsychiatric disorders in dementia and methods of their correctionКогнитивные и некогнитивные нейропсихические расстройства при деменции и методы их коррекцииМенделевичЕ. Г.MendelevichE. G.

Кафедра неврологии и реабилитации 

420012, Казань, ул. Бутлерова, 49

Department of Neurology and Rehabilitation

49, Butlerov St., Kazan 420012 

emendel@mail.ruФГБОУ ВО «Казанский государственный медицинский университет» Минздрава России, КазаньРоссияKazan State Medical University, Ministry of Health of Russia, KazanRussian Federation201702072017926570Copyright © Mendelevich E.G., 20172017Менделевич Е.Г.Mendelevich E.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/749

Dementia is an etiologically heterogeneous syndrome, the traditional evaluation of the severity of which is based on the degree of cognitive activity reduction and on impairments in functional abilities. In addition to cognitive impairment (CI), non-cognitive neuropsychiatric disorders, the prevalence of which is as high as 50–100%, form the clinical picture of dementia. Non-cognitive impairment is appreciably correlated with the severity, course, and poorest outcome of dementia. Non-cognitive neuropsychiatric impairment is characterized by different symptoms, which is associated with the heterogeneity of dementia. The main symptoms include aggression, agitation, wandering, hoarding, sexual disinhibition, apathy, depression, and anxiety. The paper considers the main clusters of neuropsychiatric disorders and their clinical manifestations. It provides data on the combination treatment of CI and non-cognitive disorders in dementia. 

Деменция – этиологически гетерогенный синдром, традиционная оценка тяжести которого основана на степени снижения познавательной деятельности и нарушения функциональных способностей. Кроме когнитивных нарушений (КН), клиническую картину деменции формируют некогнитивные нейропсихические расстройства, распространенность которых достигает 50–100%. Некогнитивные нарушения в значительной мере связаны с тяжестью, течением и худшим исходом деменции. Нейропсихические некогнитивные расстройства характеризуются различными симптомами, что связано с гетерогенностью деменции. Основные проявления включают в себя агрессию, ажитацию, блуждание, накопительство, сексуальную расторможенность, апатию, депрессию и тревогу. В статье рассмотрены основные кластеры нейропсихических расстройств, их клинические проявления. Приведены данные о комплексном лечении КН и некогнитивных расстройств при деменции. 

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The authors declare that there are no conflicts of interest present.