nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2017-1-101-105nnp-706Research ArticleREVIEWSОБЗОРЫThe clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's diseaseКлинические особенности, диагностика и лечение когнитивных расстройств при болезни ПаркинсонаАхмадееваГ. Н.AkhmadeevaG. N.

Кафедра неврологии с курсами нейрохирургии и медицинской генетики

450000, Уфа, ул. Ленина, 3

450075, Уфа, ул. Комсомольская, 133/1

Department of Neurology with Courses of Neurosurgery and Medical Genetics

3, Lenin St., Ufa 450000

133/1, Komsomolskaya St., 450075

МагжановР. В.MagzhanovR. V.

Кафедра неврологии с курсами нейрохирургии и медицинской генетики

450000, Уфа, ул. Ленина, 3

Department of Neurology with Courses of Neurosurgery and Medical Genetics

3, Lenin St., Ufa 450000

ТаюповаГ. Н.TayupovaG. N.

Кафедра неврологии с курсами нейрохирургии и медицинской генетики

450000, Уфа, ул. Ленина, 3

450075, Уфа, ул. Комсомольская, 133/1

Department of Neurology with Courses of Neurosurgery and Medical Genetics

3, Lenin St., Ufa 450000

133/1, Komsomolskaya St., 450075

БайтимеровА. Р.BaitimerovA. R.

450075, Уфа, ул. Комсомольская, 133/1

133/1, Komsomolskaya St., 450075

ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России Республиканский консультативно-диагностический центр экстрапирамидной патологии и ботулинотерапии ООО «Национальный медицинский холдинг «Медстандарт»РоссияBashkir State Medical University, Ministry of Health of Russia Republic Consulting and Diagnostic Center of Extrapyramidal Pathology and Botulinum Toxin Therapy, OOO «Medstandart» National Medical HoldingRussian FederationФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава РоссииРоссияBashkir State Medical University, Ministry of Health of RussiaRussian FederationРеспубликанский консультативно-диагностический центр экстрапирамидной патологии и ботулинотерапии ООО «Национальный медицинский холдинг «Медстандарт»РоссияRepublic Consulting and Diagnostic Center of Extrapyramidal Pathology and Botulinum Toxin Therapy, OOO «Medstandart» National Medical HoldingRussian Federation20172703201791101105Copyright © Akhmadeeva G.N., Magzhanov R.V., Tayupova G.N., Baitimerov A.R., 20172017Ахмадеева Г.Н., Магжанов Р.В., Таюпова Г.Н., Байтимеров А.Р.Akhmadeeva G.N., Magzhanov R.V., Tayupova G.N., Baitimerov A.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/706

The review presents the data of recent studies dealing with cognitive impairments (CI) in patients with Parkinson's disease (PD) and gives their characteristics and epidemiology, the specific features of the pathogenesis and clinical manifestations, as well as current methods for their diagnosis and treatment. Moderate CIs (MCIs) occur in 18.9–55% of patients with PD; the prevalence of dementia during a cross-sectional study approaches 30%. The 2007 Movement Disorder Society criteria and algorithm for the diagnosis of dementia in PD and the 2012 criteria and the algorithm for the diagnosis of MCIs allow one to maximally accurately identify these disorders. Only rivastigmine is now recognized as effective in treating CI in PD and recommended for use. Overall, therapies for CI in PD have been inadequately investigated, making it necessary to conduct further large-scale studies.

В обзоре изложены данные недавних исследований, посвященных когнитивным нарушениям (КН) у пациентов с болезнью Паркинсона (БП): представлены их характеристика и эпидемиология, особенности патогенеза и клинических проявлений, а также современные методы диагностики и лечения. Умеренные КН (УКН) встречаются у 18,9–55% пациентов с БП; распространенность деменции при одномоментном обследовании приближается к 30%. Предложенные в 2007 г. Обществом расстройства движений (Movement Disorder Society) критерии и алгоритм для диагностики деменции при БП, а в 2012 г. – для диагностики УКН позволяют максимально точно выявить эти нарушения. В настоящее время для лечения КН при БП лишь ривастигмин признан эффективным и рекомендован к применению. В целом методы терапии КН при БП изучены недостаточно, что делает необходимым проведение дальнейших широкомасштабных исследований.

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The authors declare that there are no conflicts of interest present.