nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2011-127nnp-66Research ArticleLECTURESЛЕКЦИЯCurrent treatments for brain contusionsСовременные методы лечения ушибов головного мозгаТалыповА. Э.TalypovA. E.

Москва

Moscow

Dr.Talypov@mail.ruПетриковС. С.PetrikovS. S.

Москва

Moscow

info@ima-press.netПурасЮ. В.PurasYu. V.

Москва

Moscow

info@ima-press.netСолодовА. А.SolodovA. A.

Москва

Moscow

info@ima-press.netТитоваЮ. В.TitovaYu. V.

Москва

Moscow

info@ima-press.netНИИСП им. Н.В. СклифосовскогоРоссияN.V. Sklifosovsky Research Institute of Emergency CareRussian Federation20111603201131NO1 (2011)815Copyright © Talypov A.E., Petrikov S.S., Puras Y.V., Solodov A.A., Titova Y.V., 20112011Талыпов А.Э., Петриков С.С., Пурас Ю.В., Солодов А.А., Титова Ю.В.Talypov A.E., Petrikov S.S., Puras Y.V., Solodov A.A., Titova Y.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/66

Current surgical and medical treatments for brain contusions are analyzed in terms of the concept of primary and secondary brain injuries

Проведен анализ современных методов хирургического и консервативного лечения ушибов головного мозга с учетом концепции первичных и вторичных повреждений головного мозга.

ушиб головного мозгавторичные повреждениялечениецитиколинbrain contusionsecondary lesionstreatmentciticolineReferences<div><p>Лекции по нейрохирургии. Под ред. В.В. Крылова. М.: Медицина, 2010;318 с.</p><p>Langlois J.A., Rutland-Brown W., Wald M.M. The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil 2006;21:375-8.</p><p>Tagliaferri F. , Compagnone C., Korsic M. et al. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien) 2006;148:255-68.</p><p>Kraus M.F., Susmaras T. , Caughlin P. et al. White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain 2007;130:2508-19.</p><p>Kontos H.A., Povlishock J.T. Oxygen radicals in brain injury. Cent Nerv Syst Trauma 1986;3:257-63.</p><p>Smith S.L., Andrus P.K., Zhang J.R. et al. Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat. J Neurotrauma 1994;11:393-404.</p><p>Xiong Y., Gu Q., Peterson P.L. et al. Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J Neurotrauma 1997;14:23-34.</p><p>Singh I.N., Sullivan P.G., Deng Y. et al. Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy. J Cereb Blood Flow Metab 2006;26:1407-18.</p><p>Черепно-мозговая травма. Клиническое рук-во. Под ред. А.Н. Коновалова. Т.2. М.: Антидор, 2001; 675 с.</p><p>Temple M., O'Leary D., Faden A. The role of glutamate receptors in the pathophysiology of traumatic brain injury. In: L. Miller, R. Hayes, J. Newcomb (eds). HeadTrauma. New York: John Wiley &amp; Sons, 2001;87-113.</p><p>Marklund N., Bakshi A., Castelbuono D.J. et al. Evaluation of pharmacological treatment strategies in traumatic brain injury. Curr Pharm Des 2006;12:1645-80.</p><p>Faden A.I. Pharmacologic treatment of acute traumatic brain injury. JAMA 1996;276:569-70.</p><p>Bullock M., Lyeth B., Muizelaar J. Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies. Neurosurg 1999;45:207-17.</p><p>Faden A.I. Neuroprotection and traumatic brain injury: theoretical option or realistic proposition. Curr Opin Neurol 2002;15:707-12.</p><p>Narayan R.K., Michel M.E., Ansell B. et al. Clinical trials in head injury. J Neurotrauma 2002;19:503-57.</p><p>Maas A.I., Marmarou A., Murray G.D. et al. Prognosis and clinical trial design in traumatic brain injury: the Impact study. J Neurotrauma 2007;24:232-8.</p><p>Corwin H.L., Gettinger A., Rodriguez R.M. et al. Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial. Crit Care Med 1999;27:2346-50.</p><p>Camacho-Arroyo I., Pasapera A.M., Cerbon M.A. Regulation of progesterone receptor gene expression by sex steroid hormones in the hypothalamus and the cerebral cortex of the rabbit. Neurosci Lett 1996;214:25-8.</p><p>Wang H., Lynch J.R., Song P. et al. Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. Exp Neurol 2007;206:59-69.</p><p>Tanovic A., Alfaro V., Secades J. Citicoline in the treatment of traumatic brain injury. Drugs on today 2004 (Suppl. B):1-18.</p><p>Maas A.I. Neuroprotective agents in traumatic brain injury. Expert Opin Invest Drugs 2001;10:753-67.</p></div><br /><div><p>Лекции по нейрохирургии. Под ред. В.В. Крылова. М.: Медицина, 2010;318 с.</p><p>Langlois J.A., Rutland-Brown W., Wald M.M. The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil 2006;21:375-8.</p><p>Tagliaferri F. , Compagnone C., Korsic M. et al. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien) 2006;148:255-68.</p><p>Kraus M.F., Susmaras T. , Caughlin P. et al. White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain 2007;130:2508-19.</p><p>Kontos H.A., Povlishock J.T. Oxygen radicals in brain injury. Cent Nerv Syst Trauma 1986;3:257-63.</p><p>Smith S.L., Andrus P.K., Zhang J.R. et al. Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat. J Neurotrauma 1994;11:393-404.</p><p>Xiong Y., Gu Q., Peterson P.L. et al. Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J Neurotrauma 1997;14:23-34.</p><p>Singh I.N., Sullivan P.G., Deng Y. et al. Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy. J Cereb Blood Flow Metab 2006;26:1407-18.</p><p>Черепно-мозговая травма. Клиническое рук-во. Под ред. А.Н. Коновалова. Т.2. М.: Антидор, 2001; 675 с.</p><p>Temple M., O'Leary D., Faden A. The role of glutamate receptors in the pathophysiology of traumatic brain injury. In: L. Miller, R. Hayes, J. Newcomb (eds). HeadTrauma. New York: John Wiley &amp; Sons, 2001;87-113.</p><p>Marklund N., Bakshi A., Castelbuono D.J. et al. Evaluation of pharmacological treatment strategies in traumatic brain injury. Curr Pharm Des 2006;12:1645-80.</p><p>Faden A.I. Pharmacologic treatment of acute traumatic brain injury. JAMA 1996;276:569-70.</p><p>Bullock M., Lyeth B., Muizelaar J. Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies. Neurosurg 1999;45:207-17.</p><p>Faden A.I. Neuroprotection and traumatic brain injury: theoretical option or realistic proposition. Curr Opin Neurol 2002;15:707-12.</p><p>Narayan R.K., Michel M.E., Ansell B. et al. Clinical trials in head injury. J Neurotrauma 2002;19:503-57.</p><p>Maas A.I., Marmarou A., Murray G.D. et al. Prognosis and clinical trial design in traumatic brain injury: the Impact study. J Neurotrauma 2007;24:232-8.</p><p>Corwin H.L., Gettinger A., Rodriguez R.M. et al. Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial. Crit Care Med 1999;27:2346-50.</p><p>Camacho-Arroyo I., Pasapera A.M., Cerbon M.A. Regulation of progesterone receptor gene expression by sex steroid hormones in the hypothalamus and the cerebral cortex of the rabbit. Neurosci Lett 1996;214:25-8.</p><p>Wang H., Lynch J.R., Song P. et al. Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. Exp Neurol 2007;206:59-69.</p><p>Tanovic A., Alfaro V., Secades J. Citicoline in the treatment of traumatic brain injury. Drugs on today 2004 (Suppl. B):1-18.</p><p>Maas A.I. Neuroprotective agents in traumatic brain injury. Expert Opin Invest Drugs 2001;10:753-67.</p></div><br />

The authors declare that there are no conflicts of interest present.