nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2016-3-76-81nnp-651Research ArticleREVIEWSОБЗОРЫThe role of emotional and behavioral disorders in the development of drug dependence in patients with medication-induced headache (review)Роль эмоциональных и поведенческих расстройств в формировании лекарственной зависимости у пациентов с медикаментозно-индуцированной головной болью (обзор)ШагбазянА. Э.ShagbazyanA. E.СергеевА. В.SergeevA. V.ЕвдокимоваЕ. М.EvdokimovaE. M.КурбанбагамаеваР. Р.KurbanbagamaevaR. R.ТабееваГ. Р.TabeevaG. R.grtabeeva@gmail.comКафедра нервных болезней и нейрохирургии ФГБОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России, Москва, Россия 119021, Москва, ул. Россолимо, 11РоссияDepartment of Nervous System Diseases and Neurosurgery, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia 11, Rossolimo St., Moscow 119021Russian Federation201631102016837681Copyright © Shagbazyan A.E., Sergeev A.V., Evdokimova E.M., Kurbanbagamaeva R.R., Tabeeva G.R., 20162016Шагбазян А.Э., Сергеев А.В., Евдокимова Е.М., Курбанбагамаева Р.Р., Табеева Г.Р.Shagbazyan A.E., Sergeev A.V., Evdokimova E.M., Kurbanbagamaeva R.R., Tabeeva G.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/651

Medication-induced headache (MIH) is a variety of chronic daily headache (HA). MIH belongs to secondary (symptomatic) HA, develops as a complication of pre-existing primary cephalgia, and is caused by the overuse of drugs to relieve HA. The role of drug dependence syndrome and behavioral and emotional disorders in the development of MIH, which may be associated with dysfunction of certain brain systems that control these functions, has been recently discussed. The paper reviews the literature dealing with studies of the role of behavioral and emotional disorders and orbitofrontal cortical dysfunction in the development of drug dependence syndrome in patients with MIH. The importance of analyzing these aspects of MIH is determined by the prospects for applying alternative approaches to managing these patients.

Медикаментозно-индуцированная головная боль (МИГБ) – разновидность хронической ежедневной головной боли (ГБ). МИГБ относится к вторичной (симптоматической) ГБ, развивается как осложнение изначально имеющейся первичной цефалгии и вызвана чрезмерным употреблением средств для купирования ГБ. В последнее время обсуждается вопрос о роли синдрома зависимости и поведенческих и эмоциональных расстройств в формировании МИГБ, что может быть связано с дисфункцией определенных мозговых систем, контролирующих эти функции. Представлен обзор литературы, посвященной исследованиям роли поведенческих и эмоциональных расстройств и дисфункции орбитофронтальной коры в формировании синдрома лекарственной зависимости у пациентов с МИГБ. Важность анализа этих аспектов МИГБ определяется перспективами использования альтернативных подходов к ведению этих пациентов.

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The authors declare that there are no conflicts of interest present.