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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2016-2-31-35</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-605</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Anosognosia in patients with acute hemispheric ischemic stroke</article-title><trans-title-group xml:lang="ru"><trans-title>Анозогнозия у больных острым полушарным ишемическим инсультом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьева</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoryeva</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра неврологии, нейрохирургии и медицинской генетики </p><p>603950, Нижний Новгород, площадь Минина и Пожарского, 10/1</p></bio><bio xml:lang="en"><p>Department of Neurology, Neurosurgery, and Medical Genetics</p></bio><email xlink:type="simple">vrgr@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокина</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokina</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра неврологии, нейрохирургии и медицинской генетики </p><p>603950, Нижний Новгород, площадь Минина и Пожарского, 10/1</p></bio><bio xml:lang="en"><p>Department of Neurology, Neurosurgery, and Medical Genetics</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Нижегородская государственная медицинская академия» Минздрава России, Нижний Новгород</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nizhny Novgorod State Medical Academy, Ministry of Health of Russia, Nizhny Novgorod</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>16</day><month>07</month><year>2016</year></pub-date><volume>8</volume><issue>2</issue><fpage>31</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Grigoryeva V.N., Sorokina T.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Григорьева В.Н., Сорокина Т.А.</copyright-holder><copyright-holder xml:lang="en">Grigoryeva V.N., Sorokina T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/605">https://nnp.ima-press.net/nnp/article/view/605</self-uri><abstract><sec><title>Objective</title><p>Objective: to investigate the frequency of anosognosia (a deficit of self-awareness), its anatomic correlates associated with other neuropsychological and neurological disorders in acute hemispheric ischemic stroke (IS).</p><p>Patients and methods 150 patients (83 men and 67 women; mean age, 63.0±9.3 years) with acute hemispheric IS were examined. All the patients underwent neurological, neuroimaging, and neuropsychological (by the procedure described by A.R. Luria) examinations. neuropsychological investigations. Anosognosia was diagnosed using the Dysexecutive Questionnaire (DEX) and the authors' procedure involving a scale to measure impaired self-rating of motor abilities and a scale to measure impaired self-rating of cognitive abilities in everyday life.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. In the acute period of hemispheric IS, reduced self-awareness of motor and cognitive abilities was noted in 14% of the patients and unawareness of only cognitive abilities was recorded in 15%. Patients with anosognosia and cognitive dysfunction (ACD) and those with anosognosia and motor dysfunction (AMD) had right-sided hemispheric IS more frequently (76%) while this was not found in patients with isolated ACD. The development of anosognosia for paralysis and paresis was favored by the large sizes of an ischemic focus that involved a few lobes in the posterior regions of the brain although no lesions were found in the anosognosia-specific anatomical regions. ACD and AMD proved to be associated with unilateral spatial and tactile neglect and obvious regulatory dysfunction. </p></sec></abstract><trans-abstract xml:lang="ru"><p>Цель исследования – изучение частоты анозогнозии (нарушение осознания), ее анатомических коррелятов во взаимосвязи с другими нейропсихологическими и неврологическими расстройствами в остром периоде полушарного ишемического инсульта (ИИ).</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Обследовано 150 больных в остром периоде полушарного ИИ (83 мужчины, 67 женщин, средний возраст – 63,0±9,3 года). Всем больным проводилось неврологическое, нейровизуализационное и нейропсихологическое (по методике А.Р. Лурия) обследование. Для диагностики анозогнозии применяли «Опросник нарушений исполнительных функций» (Dysexecutive Questionnaire, DEX) и собственную методику, включающую шкалу для измерения нарушения самооценки двигательных возможностей и шкалу для измерения нарушения самооценки когнитивных возможностей в повседневной жизни.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В остром периоде полушарного ИИ снижение осознания двигательных и когнитивных возможностей отмечалось у 14% пациентов, а нарушение осознания только когнитивных возможностей – у 15%. Больные с анозогнозией и когнитивной (АКД), и двигательной (АДД) дисфункции чаще (в 76% случаев) имели правополушарную локализацию ИИ, в то время как у пациентов с изолированной АКД такой закономерности не обнаружено.</p><p>Развитию анозогнозии параличей и парезов способствовали большие размеры очага ишемии, вовлекавшего несколько долей в задних отделах головного мозга, хотя повреждения специфических для анозогнозии анатомических областей не выявлено.</p><p>АКД и АДД оказалась сопряжена с наличием одностороннего пространственного и тактильного неглекта, а также с выраженной регуляторной дисфункцией. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемический инсульт</kwd><kwd>анозогнозия</kwd><kwd>регуляторная дисфункция</kwd><kwd>неглект</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic stroke</kwd><kwd>anosognosia</kwd><kwd>regulatory dysfunction</kwd><kwd>neglect</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гусев ЕИ. 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