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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2016-1-61-70</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-585</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Hemorrhagic stroke and oral anticoagulants: What is to be done?</article-title><trans-title-group xml:lang="ru"><trans-title>Геморрагический инсульт и оральные антикоагулянты: что делать?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Домашенко</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Domashenko</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">mdomashenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научный центр неврологии», Москва, Россия 125367, Москва, Волоколамское шоссе, 80</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Neurology Research Center, Moscow, Russia 80, Volokolamskoe Shosse, Moscow 125367</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>22</day><month>03</month><year>2016</year></pub-date><volume>8</volume><issue>1</issue><fpage>61</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Domashenko M.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Домашенко М.А.</copyright-holder><copyright-holder xml:lang="en">Domashenko M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/585">https://nnp.ima-press.net/nnp/article/view/585</self-uri><abstract><p>Hemorrhagic stroke (HS) is associated with high mortality and disability rates. Due to the introduction of the current guidelines for the prevention of systemic thromboembolic events in patients with atrial fibrillations and to an increase in the number of older patients, there has been a rise in the incidence of intracranial hemorrhage (ICH) associated with the use of oral anticoagulants. The paper discusses medical treatment in patients with HS during therapy with vitamin K antagonists (warfarin) and novel oral anticoagulants (dabigatran. rivaroxaban, apixaban), as well as an anticoagulant resumption policy after prior ICH in patients at high risk for thromboembolic events.</p></abstract><trans-abstract xml:lang="ru"><p>Геморрагический инсульт (ГИ, внутричерепное кровоизлияние – ВЧК) сопряжен с высокими показателями летальности и инвалидизации. На фоне внедрения современных рекомендаций по профилактике системных тромбоэмболических осложнений у пациентов с фибрилляцией предсердий, а также увеличения числа пациентов старшего возраста, наблюдается повышение частоты ВЧК, ассоциированных с применением оральных антикоагулянтов. В статье обсуждаются вопросы консервативного лечения пациентов с ГИ на фоне терапии антагонистами витамина К (варфарин) и новыми оральными антикоагулянтами (дабигатран, ривароксабан, апиксабан), а также тактика возобновления приема антикоагулянтов после перенесенного ВЧК у пациентов с высоким риском тромбоэмболических осложнений.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>геморрагический инсульт (внутричерепное кровоизлияние)</kwd><kwd>оральные антикоагулянты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hemorrhagic stroke</kwd><kwd>oral anticoagulants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Feigin VL, Lawes CM, Bennett DA, et al. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol. 2009 Apr;8(4):355-69. doi: 10.1016/S1474- 4422(09)70025-0. 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