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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2010-88</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-44</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHARMACOECONOMICS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОЭКОНОМИКА</subject></subj-group></article-categories><title-group><article-title>Pharmacoeconomic analysis of cost-benefit in evaluating the effectiveness of treatment for epilepsy in adults</article-title><trans-title-group xml:lang="ru"><trans-title>Фармакоэкономический анализ «стоимость-эффективность» в оценке результативности лечения эпилепсии у взрослых</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власов</surname><given-names>П. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasov</surname><given-names>P. N.</given-names></name></name-alternatives><email xlink:type="simple">vpn_neuro@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орехова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orekhova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">info@ima-press.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леонова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leonova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@ima-press.net</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МГМСУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>РГМУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>13</day><month>06</month><year>2010</year></pub-date><volume>2</volume><issue>2</issue><issue-title>NO2 (2010)</issue-title><fpage>66</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Vlasov P.N., Orekhova N.V., Leonova M.V., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Власов П.Н., Орехова Н.В., Леонова М.В.</copyright-holder><copyright-holder xml:lang="en">Vlasov P.N., Orekhova N.V., Leonova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/44">https://nnp.ima-press.net/nnp/article/view/44</self-uri><abstract><p>The investigation evaluated the clinicoeconomic benefits of epilepsy therapy performed by a district neurologist versus an epileptologist in the outpatient setting. The index «cost-benefit» was calculated for different types of epileptic seizures in employed and unemployed patients before and after therapy optimization. Even if there was a considerable increase in direct costs after correction of antiepileptic therapy, the cost of patient management was shown to decrease by 2-3 times on average irrespective of the type of a seizure.</p></abstract><trans-abstract xml:lang="ru"><p>С целью оптимизации медикаментозной терапии у пациентов с эпилепсией и оценки клинико-экономической эффективности лечения эпилепсии на амбулаторном приеме у эпилептолога проанализированы данные обследования и наблюдения 1678 пациентов консультативно-диагностического центра городской поликлиники № 180 и кафедры нервных болезней МГМСУ. Показано, что даже при значительном росте прямых затрат при адекватной противоэпилептической терапии стоимость лечения снижается в среднем в 2-3 раза независимо от типа эпилептических припадков.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>анализ «стоимость-эффективность»</kwd></kwd-group><kwd-group xml:lang="en"><kwd>adult epilepsy</kwd><kwd>pharmacoeconomic analysis</kwd><kwd>cost-benefit</kwd><kwd>antiepileptics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Карлов В.А. Эпилепсия. М.: Медицина, 1990.&lt;/p&gt;&lt;p&gt;Devinsky O., Westbrook L., Cramer J. et al. Risk factors for poor health-related quality of life in adolescents with epilepsy. Epilepsia 1999; 40: 1715-20.&lt;/p&gt;&lt;p&gt;Brodie M.J., Mohanraj R. Response to treatment in newly diagnosed epilepsy. Epilepsia 2003; 44(Suppl. 9): 14.&lt;/p&gt;&lt;p&gt;Гехт А.Б. Эпидемиология и фармакоэко- номические аспекты эпилепсии. Журн. неврол. и психиатр. им. С.С.Корсакова 2005; 105(8): 63-5.&lt;/p&gt;&lt;p&gt;Мухин К.Ю., Петрухин А.С. Идиопатические формы эпилепсии: систематика, диагностика, терапия. М.: Арт-Бизнес-центр, 2000.&lt;/p&gt;&lt;p&gt;Власов П.Н. Алгоритмы диагностики и терапии эпилепсии у взрослых в поликлинических условиях. Фарматека 2006; 7: 96-104.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Карлов В.А. Эпилепсия. М.: Медицина, 1990.&lt;/p&gt;&lt;p&gt;Devinsky O., Westbrook L., Cramer J. et al. Risk factors for poor health-related quality of life in adolescents with epilepsy. Epilepsia 1999; 40: 1715-20.&lt;/p&gt;&lt;p&gt;Brodie M.J., Mohanraj R. Response to treatment in newly diagnosed epilepsy. Epilepsia 2003; 44(Suppl. 9): 14.&lt;/p&gt;&lt;p&gt;Гехт А.Б. Эпидемиология и фармакоэко- номические аспекты эпилепсии. Журн. неврол. и психиатр. им. С.С.Корсакова 2005; 105(8): 63-5.&lt;/p&gt;&lt;p&gt;Мухин К.Ю., Петрухин А.С. Идиопатические формы эпилепсии: систематика, диагностика, терапия. М.: Арт-Бизнес-центр, 2000.&lt;/p&gt;&lt;p&gt;Власов П.Н. Алгоритмы диагностики и терапии эпилепсии у взрослых в поликлинических условиях. Фарматека 2006; 7: 96-104.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
