References

nnp

Neurology, Neuropsychiatry, Psychosomatics

Неврология, нейропсихиатрия, психосоматика

2074-27112310-1342

"IMA-Press", LLC

10.14412/2074-2711-2014-1-61-67

nnp-383

Research Article

REVIEWS

ОБЗОРЫ

Dementia of the Alzheimer type: current state of the problem

Деменции альцгеймеровского типа: современное состояние проблемы

Тювина

Н.А.

Tyuvina

N.A.

1@ru.ru

Балабанова

В.В.

Balabanova

V.V.

1@ru.ru

Кафедра психиатрии и наркологии ГБОУ ВПО «Первый Московский медицинский государственный университет им. И.М. Сеченова» Минздрава России, Москва, РоссияРоссияDepartment of Psychiatry and Addiction Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, RussiaRussian Federation

2014

05052014

616167

2014

Тювина Н., Балабанова В.

Tyuvina N., Balabanova V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://nnp.ima-press.net/nnp/article/view/383

The current knowledge on epidemiology, diagnosis, and treatment of Alzheimer's disease and dementia of the Alzheimer type are presented. Various approaches to therapy based on current understanding of the pathogenesis of the degenerative process are discussed with allowance for the clinical features of the disease (psychopathologic symptoms and stage of the disease). Special attention is paid to compensatory therapy aimed at compensating for the deficit in cholinergic and glutamatergic neurotransmission.

Представлены современные данные об эпидемиологии, диагностике и лечении болезни Альцгеймера и деменции альцгеймеровского типа. Рассмотрены различные подходы к терапии на основе современных представлений о патогенезе дегенеративного процесса и с учетом клинических особенностей заболевания (характера психопатологической симптоматики, стадии болезни). Особое внимание уделено компенсаторной терапии, направленной на восполнение дефицита холинергической и глутаматергической нейротрансмиссии.

болезнь Альцгеймерадеменция альцгеймеровского типаэпидемиологиядиагностикатерапияингибиторы ацетилхолинэстеразыакатинол.

Alzheimer's diseasedementia of the Alzheimer typeepidemiologydiagnosticstherapyacetylcholinesterase inhibitorsAkatinol Memantine.

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The authors declare that there are no conflicts of interest present.