Low back pain is stated to be of muscular origin, it is somewhat less frequently associated with osteochondrosis or/and spondyloarthrosis. While examining a patient with back pain, it is necessary to exclude rare causes (fractures, neoplasms, etc.) that require special management. The diagnosis is established on the basis of physical, neurological, manual, and orthopedic studies. The presence of herniated disks, particularly those of small sizes detectable by computed tomography or magnetic resonance imaging, does not rule out any other cause of back pain. Musculoskeletal pain management is noted to relieve the pain, by returning the patient to an active life as soon as possible. Nonsteroidal anti-inflammatory drugs and myorelaxants are beneficial for pain relief. In chronic back pain, antidepressants are effective in case of depression; the occupational, social, and everyday rehabilitations are of great value.