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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2026-2-74-78</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2818</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Treatment of patients with comorbid pain syndromes: an effective and safe approach</article-title><trans-title-group xml:lang="ru"><trans-title>Лечение пациента с коморбидными болевыми синдромами: эффективный и безопасный подход</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2752-4109</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вероника Александровна Головачева</p><p>Институт клинической медицины им. Н.В. Склифосовского; кафедра нервных болезней </p><p>119021; ул. Россолимо, 11, стр. 1; Москва</p></bio><bio xml:lang="en"><p>Veronika Alexandrovna Golovacheva</p><p>N.V. Sklifosovsky Institute of Clinical Medicine; Department of Nervous Diseases</p><p>119021; 11, Rossolimo St., Build. 1; Moscow</p></bio><email xlink:type="simple">xoxo.veronicka@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2845-7323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Институт клинической медицины им. Н.В. Склифосовского; кафедра нервных болезней </p><p>119021; ул. Россолимо, 11, стр. 1; Москва</p></bio><bio xml:lang="en"><p>N.V. Sklifosovsky Institute of Clinical Medicine; Department of Nervous Diseases</p><p>119021; 11, Rossolimo St., Build. 1; Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>24</day><month>04</month><year>2026</year></pub-date><volume>18</volume><issue>2</issue><fpage>74</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Golovacheva V.A., Golovacheva A.A., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Головачева В.А., Головачева А.А.</copyright-holder><copyright-holder xml:lang="en">Golovacheva V.A., Golovacheva A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2818">https://nnp.ima-press.net/nnp/article/view/2818</self-uri><abstract><p>   Patients with comorbid pain syndromes are frequently encountered in neurological practice. The management of patients with chronic musculoskeletal pain in the neck and back, and primary headaches, requires a comprehensive approach based on a combination of non-pharmacological methods and optimized pharmacotherapy. A clinical case is described of the effective management of a female patient suffering from chronic non-specific cervicobrachialgia, episodic tension-type headache involving the pericranial muscles, episodic migraine without aura, and increased anxiety. A comprehensive approach was used in the patient's management, which included optimal pharmacotherapy and a combination of non-pharmacological methods. Pharmacotherapy consisted of a stepwise course of Dexalgin (dexketoprofen). Non-pharmacological therapy included in-depth educational discussions with the patient about the condition, individual kinesiotherapy, and training in ergonomics. After 3 months of treatment, the patient's neck pain had subsided, tension-type headaches were no longer present, and the frequency of migraine attacks had significantly decreased. The improvements achieved were maintained throughout the one-year follow-up period. The optimization of the management of patients with comorbid pain syndromes is discussed.</p></abstract><trans-abstract xml:lang="ru"><p>   Пациенты с коморбидными болевыми синдромами часто встречаются в неврологической практике. Ведение пациента с хронической скелетно-мышечной болью в шее и спине, первичной головной болью требует комплексного подхода, который основан на сочетании нелекарственных методов и оптимизации лекарственной терапии. Описан клинический случай эффективного ведения пациентки, страдающей хронической неспецифической цервикобрахиалгией, эпизодической головной болью напряжения (ГБН) с вовлечением перикраниальных мышц, эпизодической мигренью без ауры и повышенной тревогой. При ведении пациентки применялся комплексный подход, который включал оптимальную лекарственную терапию и комбинацию нелекарственных методов. Лекарственная терапия состояла из ступенчатого курса приема препарата Дексалгин (декскетопрофен). Нелекарственная терапия включала расширенные образовательные беседы с пациенткой о заболевании, индивидуальную кинезиотерапию и обучение эргономике. Через 3 мес лечения у пациентки регрессировала боль в шее, не отмечалась ГБН, значимо снизилась частота приступов мигрени. Достигнутые улучшения сохранились в течение года наблюдения. Обсуждается оптимизация ведения пациентов с коморбидными болевыми синдромами.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль в шее</kwd><kwd>цервикобрахиалгия</kwd><kwd>скелетно-мышечная боль</kwd><kwd>коморбидные нарушения</kwd><kwd>лечение</kwd><kwd>кинезиотерапия</kwd><kwd>лечебная гимнастика</kwd><kwd>эргономика</kwd><kwd>фармакотерапия</kwd><kwd>декскетопрофен</kwd><kwd>Дексалгин</kwd><kwd>нестероидные противовоспалительные препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neck pain</kwd><kwd>cervicobrachialgia</kwd><kwd>musculoskeletal pain</kwd><kwd>comorbid conditions</kwd><kwd>treatment</kwd><kwd>kinesiotherapy</kwd><kwd>therapeutic exercise</kwd><kwd>ergonomics</kwd><kwd>pharmacotherapy</kwd><kwd>dexketoprofen</kwd><kwd>Dexalgin</kwd><kwd>non-steroidal anti-inflammatory drugs</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование не имело спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The investigation has not been sponsored</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bikbov MM, Kazakbaeva GM, Zainullin RM, et al. Prevalence of and factors associated with low Back pain, thoracic spine pain and neck pain in Bashkortostan, Russia: the Ural Eye and Medical Study. BMC Musculoskelet Disord. 2020;21(1):64. doi: 10.1186/s12891-020-3080-4</mixed-citation><mixed-citation xml:lang="en">Bikbov MM, Kazakbaeva GM, Zainullin RM, et al. Prevalence of and factors associated with low Back pain, thoracic spine pain and neck pain in Bashkortostan, Russia: the Ural Eye and Medical Study. BMC Musculoskelet Disord. 2020;21(1):64. doi: 10.1186/s12891-020-3080-4</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Popescu A, Lee H. Neck Pain and Lower Back Pain. Med Clin North Am. 2020;104(2):279-92. doi: 10.1016/j.mcna.2019.11.003</mixed-citation><mixed-citation xml:lang="en">Popescu A, Lee H. Neck Pain and Lower Back Pain. Med Clin North Am. 2020;104(2):279-92. doi: 10.1016/j.mcna.2019.11.003</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Hoy DG, Protani M, De R, Buchbinder R. The epidemiology of neck pain. Best Pract Res Clin Rheumatol. 2010;24(6):783-92. doi: 10.1016/j.berh.2011.01.019</mixed-citation><mixed-citation xml:lang="en">Hoy DG, Protani M, De R, Buchbinder R. The epidemiology of neck pain. Best Pract Res Clin Rheumatol. 2010;24(6):783-92. doi: 10.1016/j.berh.2011.01.019</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kazeminasab S, Nejadghaderi SA, Amiri P, et al. Neck pain: global epidemiology, trends and risk factors. BMC Musculoskelet Disord. 2022;23(1):26. doi: 10.1186/s12891-021-04957-4</mixed-citation><mixed-citation xml:lang="en">Kazeminasab S, Nejadghaderi SA, Amiri P, et al. Neck pain: global epidemiology, trends and risk factors. BMC Musculoskelet Disord. 2022;23(1):26. doi: 10.1186/s12891-021-04957-4</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ashina S, Bendtsen L, Lyngberg AC, et al. Prevalence of neck pain in migraine and tension-type headache: a population study. Cephalalgia. 2015;35(3):211-9. doi: 10.1177/0333102414535110</mixed-citation><mixed-citation xml:lang="en">Ashina S, Bendtsen L, Lyngberg AC, et al. Prevalence of neck pain in migraine and tension-type headache: a population study. Cephalalgia. 2015;35(3):211-9. doi: 10.1177/0333102414535110</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Yu Z, Wang R, Ao R, Yu S. Neck pain in episodic migraine: a cross-sectional study. J Pain Res. 2019;12:1605-13. doi: 10.2147/JPR.S200606</mixed-citation><mixed-citation xml:lang="en">Yu Z, Wang R, Ao R, Yu S. Neck pain in episodic migraine: a cross-sectional study. J Pain Res. 2019;12:1605-13. doi: 10.2147/JPR.S200606</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lampl C, Rudolph M, Deligianni CI, Mitsikostas DD. Neck pain in episodic migraine: premonitory symptom or part of the attack? J Headache Pain. 2015;16:566. doi: 10.1186/s10194-015-0566-9</mixed-citation><mixed-citation xml:lang="en">Lampl C, Rudolph M, Deligianni CI, Mitsikostas DD. Neck pain in episodic migraine: premonitory symptom or part of the attack? J Headache Pain. 2015;16:566. doi: 10.1186/s10194-015-0566-9</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">May A, Schulte LH. Chronic migraine: risk factors, mechanisms and treatment. Nat Rev Neurol. 2016;12(8):455-64. doi: 10.1038/nrneurol.2016.93</mixed-citation><mixed-citation xml:lang="en">May A, Schulte LH. Chronic migraine: risk factors, mechanisms and treatment. Nat Rev Neurol. 2016;12(8):455-64. doi: 10.1038/nrneurol.2016.93</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Pradhan S, Choudhury SS. Clinical characterization of neck pain in migraine. Neurol India. 2018;66(2):377-84. doi: 10.4103/0028-3886.227302</mixed-citation><mixed-citation xml:lang="en">Pradhan S, Choudhury SS. Clinical characterization of neck pain in migraine. Neurol India. 2018;66(2):377-84. doi: 10.4103/0028-3886.227302</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Головачева ВА, Головачева АА. Лечение хронической мигрени и боли в шее с помощью когнитивно-поведенческой терапии. Клинический случай. Consilium Medicum. 2021;23(11):852-7. doi: 10.26442/20751753.2021.11.201137</mixed-citation><mixed-citation xml:lang="en">Golovacheva VA, Golovacheva AA. Treatment of chronic migraine and neck pain with cognitive-behavioral therapy. Case report. Consilium Medicum. 2021;23(11):852-7 (In Russ.). doi: 10.26442/20751753.2021.11.201137</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bartsch T, Goadsby PJ. The trigeminocervical complex and migraine: current concepts and synthesis. Curr Pain Headache Rep. 2003;7(5):371-6. doi: 10.1007/s11916-003-0036-y</mixed-citation><mixed-citation xml:lang="en">Bartsch T, Goadsby PJ. The trigeminocervical complex and migraine: current concepts and synthesis. Curr Pain Headache Rep. 2003;7(5):371-6. doi: 10.1007/s11916-003-0036-y</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Busch V, Jakob W, Juergens T, et al. Functional connectivity between trigeminal and occipital nerves revealed by occipital nerve blockade and nociceptive blink reflexes. Cephalalgia. 2006;26(1):50-5. doi: 10.1111/j.1468-2982.2005.00992.x</mixed-citation><mixed-citation xml:lang="en">Busch V, Jakob W, Juergens T, et al. Functional connectivity between trigeminal and occipital nerves revealed by occipital nerve blockade and nociceptive blink reflexes. Cephalalgia. 2006;26(1):50-5. doi: 10.1111/j.1468-2982.2005.00992.x</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Головачева ВА, Головачева АА. Хроническая боль в шее и сочетанная головная боль напряжения: единый эффективный подход к лечению. Неврология, нейропсихиатрия, психосоматика. 2024;16(4):76-84. doi: 10.14412/2074-2711-2024-4-76-84</mixed-citation><mixed-citation xml:lang="en">Golovacheva VA, Golovacheva AA. Chronic neck pain and combined tension headache: a unified effective treatment approach. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2024;16(4):76-84 (In Russ.). doi: 10.14412/2074-2711-2024-4-76-84</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Строков ИА, Головачева АА, Фатеева ТГ. Лечение хронической цервикобрахиалгии с использованием кинезиотерапии. Неврология, нейропсихиатрия, психосоматика. 2025;17(2):76-81. doi: 10.14412/2074-2711-2025-2-76-81</mixed-citation><mixed-citation xml:lang="en">Strokov IA, Golovacheva AA, Fateeva TG. Treatment of chronic cervicobrachialgia with the help of kinesiotherapy. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2025;17(2):76-81 (In Russ.). doi: 10.14412/2074-2711-2025-2-76-81</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3&lt;sup&gt;rd&lt;/sup&gt; ed. Cephalalgia. 2018;38(1):1-211. doi: 10.1177/0333102417738202</mixed-citation><mixed-citation xml:lang="en">Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3&lt;sup&gt;rd&lt;/sup&gt; ed. Cephalalgia. 2018;38(1):1-211. doi: 10.1177/0333102417738202</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Парфенов ВА, Яхно НН, Кукушкин МЛ и др. Неспецифическая боль в шее (цервикалгия). Рекомендации Российского общества по изучению боли (РОИБ). Неврология, нейропсихиатрия, психосоматика. 2023;15(5):4-12. doi: 10.14412/2074-27112023-5-4-12</mixed-citation><mixed-citation xml:lang="en">Parfenov VA, Yakhno NN, Kukushkin ML, et al. Non-specific neck pain (cervicalgia). Guidelines of the Russian Society for the Study of Pain (RSSP). Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2023;15(5):4-12 (In Russ.). doi: 10.14412/2074-27112023-5-4-12</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Castien R, Duineveld M, Maaskant J, et al. Pericranial Total Tenderness Score in Patients with Tension-type Headache and Migraine. A Systematic Review and Meta-analysis. Pain Phys. 2021;24(8):E1177-E1189. Available at: https://www.painphysicianjournal.com/link-out?issn=&amp;page=E1177&amp;vol=24</mixed-citation><mixed-citation xml:lang="en">Castien R, Duineveld M, Maaskant J, et al. Pericranial Total Tenderness Score in Patients with Tension-type Headache and Migraine. A Systematic Review and Meta-analysis. Pain Phys. 2021;24(8):E1177-E1189. Available at: https://www.painphysicianjournal.com/link-out?issn=&amp;page=E1177&amp;vol=24</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rota E, Evangelista A, Ceccarelli M, et al. Efficacy of a workplace relaxation exercise program on muscle tenderness in a working community with headache and neck pain: a longitudinal, controlled study. Eur J Phys Rehabil Med. 2016;52(4):457-65. Available at: https://www.minervamedica.it/en/journals/europa-medicophysica/article.php?cod=R33Y2016N04A0457</mixed-citation><mixed-citation xml:lang="en">Rota E, Evangelista A, Ceccarelli M, et al. Efficacy of a workplace relaxation exercise program on muscle tenderness in a working community with headache and neck pain: a longitudinal, controlled study. Eur J Phys Rehabil Med. 2016;52(4):457-65. Available at: https://www.minervamedica.it/en/journals/europa-medicophysica/article.php?cod=R33Y2016N04A0457</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hosseinifar M, Bazghandi R, Azimi Z, Bohlouli BK. Glob Effectiveness of Neck Myofascial Release Techniques and Exercise Therapy on Pain Intensity and Disability in Patients with Chronic Tension-Type Headache. J Health Sci. 2016: 9(6):47. doi: 10.5539/gjhs.v9n6p47</mixed-citation><mixed-citation xml:lang="en">Hosseinifar M, Bazghandi R, Azimi Z, Bohlouli BK. Glob Effectiveness of Neck Myofascial Release Techniques and Exercise Therapy on Pain Intensity and Disability in Patients with Chronic Tension-Type Headache. J Health Sci. 2016: 9(6):47. doi: 10.5539/gjhs.v9n6p47</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Johnston V, Chen X, Welch A, et al. A cluster-randomized trial of workplace ergonomics and neck-specific exercise versus ergonomics and health promotion for office workers to manage neck pain – a secondary outcome analysis. BMC Musculoskelet Disord. 2021;22(1):68. doi: 10.1186/s12891-021-03945-y</mixed-citation><mixed-citation xml:lang="en">Johnston V, Chen X, Welch A, et al. A cluster-randomized trial of workplace ergonomics and neck-specific exercise versus ergonomics and health promotion for office workers to manage neck pain – a secondary outcome analysis. BMC Musculoskelet Disord. 2021;22(1):68. doi: 10.1186/s12891-021-03945-y</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Shariat A, Cleland JA, Danaee M, et al. Effects of stretching exercise training and ergonomic modifications on musculoskeletal discomforts of office workers: a randomized controlled trial. Braz J Phys Ther. 2018;22(2):144-53. doi: 10.1016/j.bjpt.2017.09.003</mixed-citation><mixed-citation xml:lang="en">Shariat A, Cleland JA, Danaee M, et al. Effects of stretching exercise training and ergonomic modifications on musculoskeletal discomforts of office workers: a randomized controlled trial. Braz J Phys Ther. 2018;22(2):144-53. doi: 10.1016/j.bjpt.2017.09.003</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Соловьева ЭЮ, Карнеев АН, Иваноков АН, Джутова ЭД. Декскетопрофен в лечении острой боли в спине. Эффективная фармакотерапия. Неврология и психиатрия. 2012;(5):36-40. Доступно по ссылке: https://umedp.ru/articles/dekske-toprofen_v_lechenii_ostroy_boli_v_spine.html</mixed-citation><mixed-citation xml:lang="en">Solovieva EYu, Karneev AN, Ivanokov AN, Dzhutova ED. Dexketoprofen in the treatment of acute back pain. Effective Pharmacotherapy. Neurology and Psychiatry. 2012;(5):36-40. Available at: https://umedp.ru/articles/dekske-toprofen_v_lechenii_ostroy_boli_v_spine.html (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Gaskell H, Derry S, Wiffen PJ, Moore RA. Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults. Cochrane Database Syst Rev. 2017 May 25;5(5):CD007355. doi: 10.1002/14651858.CD007355.pub3</mixed-citation><mixed-citation xml:lang="en">Gaskell H, Derry S, Wiffen PJ, Moore RA. Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults. Cochrane Database Syst Rev. 2017 May 25;5(5):CD007355. doi: 10.1002/14651858.CD007355.pub3</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Шавловская ОА. Оценка эффективности терапевтического действия препарата Дексалгин® (декскетопрофена трометамол) в лечении дорсопатии. Consilium Medicum. Неврология и ревматология (Прил.). 2012;(2):66-9. Доступно по ссылке: https://omnidoctor.ru/library/izdaniya-dlya-vrachey/consilium-medicum/cm2012/nevro_2012_pril/nevro2012_2_pril/otsenka-effektivnosti-terapevticheskogo-deystviya-preparata-deksalgin-deksketoprofena-trometa-mol-v-l/</mixed-citation><mixed-citation xml:lang="en">Shavlovskaya OA. Evaluation of the effectiveness of the therapeutic action of the drug Dexalgin (dexketoprofen trometamol) in the treatment of dorsopathy. Consilium Medicum. Neurology and Rheumatology (Suppl.). 2012;(2):66-9. Available at: https://omnidoctor.ru/library/izdaniya-dlya-vrachey/consilium-medicum/cm2012/nevro_2012_pril/nevro2012_2_pril/otsenka-effektivnosti-terapevticheskogo-deystviya-preparata-deksalgin-deksketoprofena-trometamol-v-l/ (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Moore RA, Barden J. Systematic review of dexketoprofen in acute and chronic pain. BMC Clin Pharmacol. 2008 Oct 31;8:11. doi: 10.1186/1472-6904-8-11</mixed-citation><mixed-citation xml:lang="en">Moore RA, Barden J. Systematic review of dexketoprofen in acute and chronic pain. BMC Clin Pharmacol. 2008 Oct 31;8:11. doi: 10.1186/1472-6904-8-11</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Rainsford KD. Current Status of the Therapeutic Uses and Actions of the Preferential Cyclo-Oxygenase-2 NSAID, Nimesulide. Inflammopharmacology. 2006;14(3-4):120-37. doi: 10.1007/s10787-006-1505-9</mixed-citation><mixed-citation xml:lang="en">Rainsford KD. Current Status of the Therapeutic Uses and Actions of the Preferential Cyclo-Oxygenase-2 NSAID, Nimesulide. Inflammopharmacology. 2006;14(3-4):120-37. doi: 10.1007/s10787-006-1505-9</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
