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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2025-5-55-61</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2700</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Sleep disturbance and cognitive decline in individuals aged 25–44</article-title><trans-title-group xml:lang="ru"><trans-title>Нарушение сна и снижение когнитивных функций у лиц 25–44 лет</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5701-7856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Валерий Васильевич Гафаров</p><p>630089, Новосибирск, ул. Б. Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Valery Vasilyevich Gafarov</p><p>175/1, B. Bogatkova St., Novosibirsk 630089</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1407-269X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суханов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhanov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1</p></bio><bio xml:lang="en"><p>175/1, B. Bogatkova St., Novosibirsk 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8313-3893</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1</p></bio><bio xml:lang="en"><p>175/1, B. Bogatkova St., Novosibirsk 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5255-5647</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1</p></bio><bio xml:lang="en"><p>175/1, B. Bogatkova St., Novosibirsk 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5380-9434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1</p></bio><bio xml:lang="en"><p>175/1, B. Bogatkova St., Novosibirsk 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины – филиал ФГБНУ «Федеральный исследовательский центр Институт цитологии и генетики СО РАН»; Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеваний СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute for Therapy and Preventive Medicine – the Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences; Interdepartmental Laboratory of Epidemiology of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2025</year></pub-date><volume>17</volume><issue>5</issue><fpage>55</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Gafarov V.V., Sukhanov A.V., Gromova E.A., Gagulin I.V., Gafarova A.V., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Суханов А.В., Громова Е.А., Гагулин И.В., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Sukhanov A.V., Gromova E.A., Gagulin I.V., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2700">https://nnp.ima-press.net/nnp/article/view/2700</self-uri><abstract><sec><title>Objective</title><p>Objective: to establish associations between the level of sleep disturbances (SD) and cognitive decline (CD; patterns of memory, attention, and executive functions) in individuals aged 25–44 years.</p></sec><sec><title>Material and methods</title><p>Material and methods. In 2013–2016, a survey of a random representative sample of individuals aged 25–44 was conducted in one of the districts of Novosibirsk under the World Health Organisation's MOPSY (MONICA-psychosocial) programme. The level of SD and the state of cognitive functions (CF) were assessed in 713 people (325 men and 388 women; average age – 36.17±5.99 years) according to the criteria of the World Health Organisation's MOPSY (MONICA-psychosocial) programme. Standardised tests were used to assess CF.</p></sec><sec><title>Results</title><p>Results. In a random representative sample of individuals aged 25–44, the prevalence of sleep disorders was higher among women than men (46.4% versus 40.1%, respectively). At the same time, the subjective assessment of sleep by respondents was as follows: 'satisfactory' – 35.6% and 35.5%, “poor” – 10.3% and 4.3%, 'very poor' – 0.5% and 0.3% in women and men, respectively (χ2=10.482; df=4; p&lt;0.033). It was found that when sleep was poor, men were able to name only 7.5476±1.20973 words during direct word recall in the 10-word memorization test of A.R. Luria, with satisfactory sleep – 7.5948±1.17612 words, and with good and very good sleep, they named 7.9956±0.84677 and 7.9923±0.94697 words, respectively (χ2=10.114; df=5; p=0.039). It was found that with poor sleep, men were able to view only 251.64±82.822 letters of the proofreading test in 1 minute, with satisfactory sleep – 288.36±73.961 letters. The best results for this indicator were achieved by men without SD, who were able to view 303.91±70.292 letters in 1 minute in the case of good sleep and 319.7±61.577 letters in the case of very good sleep (χ2=19.012; df=5; p=0.001). Women with sleep disturbances were able to recall 8.63±1.125 words during delayed reproduction of 10 words after an interfering task, while those with satisfactory sleep recalled 8.38±1.347 words. The best results in this test were achieved by women without SD, who were able to recall 8.76±1.387 words after good sleep and 8.69±1.398 words after very good sleep (χ2=12.264; df=5; p=0.015).</p></sec><sec><title>Conclusion</title><p>Conclusion. A population study has established an association between sleep disturbances and cognitive decline (memory, attention and executive functions patterns) in individuals aged 25–44.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цель исследования – установить ассоциации между уровнем нарушений сна (НС) и снижением когнитивных функций (КФ; паттерны памяти, внимания и мышления) у лиц 25–44 лет.</p><sec><title>Материал и методы</title><p>Материал и методы. В 2013–2016 гг. проведено обследование случайной репрезентативной выборки лиц 25–44 лет в одном из районов г. Новосибирска по программе Всемирной организации здравоохранения MOPSY (MONICA-психосоциальная). Уровень НС и состояния КФ оценивался у 713 человек (325 мужчин и 388 женщин; средний возраст – 36,17±5,99 года) по критериям программы Всемирной организации здравоохранения MOPSY (MONICA-психосоциальная). Для оценки КФ использовались стандартизированные тесты.</p></sec><sec><title>Результаты</title><p>Результаты. В обследованной случайной репрезентативной выборке лиц 25–44 лет распространенность НС у женщин была выше, чем у мужчин, (46,4% против 40,1% соответственно). При этом субъективная оценка сна респондентами составила: «удовлетворительно» – 35,6 и 35,5%, «плохо» – 10,3 и 4,3%, «очень плохо» – 0,5 и 0,3% у женщин и мужчин соответственно (χ2=10,482; df=4; p&lt;0,033). Установлено, что при плохом сне мужчины смогли назвать при непосредственном воспроизведении слов в тесте запоминания 10 слов А.Р. Лурия только 7,5476±1,20973 слова, при удовлетворительном сне – 7,5948±1,17612 слова, а при хорошем и очень хорошем сне они называли 7,9956±0,84677 и 7,9923±0,94697 слова соответственно (χ2=10,114; df=5; p=0,039). Выявлено, что при плохом сне мужчины смогли просмотреть за 1 мин только 251,64±82,822 буквы корректурной пробы, при удовлетворительном сне – 288,36±73,961 буквы. Лучшие же результаты по этому показателю были у мужчин без НС, которые смогли просмотреть за 1 мин 303,91±70,292 буквы в случае хорошего и 319,7±61,577 буквы в случае очень хорошего сна (χ2=19,012; df=5; p=0,001). Женщины с НС при отсроченном воспроизведении 10 слов после интерферирующего задания смогли вспомнить 8,63±1,125 слова, имеющие удовлетворительный сон – 8,38±1,347 слова. Лучшие показатели этого теста были у женщин без НС, которые смогли вспомнить 8,76±1,387 слова при хорошем и 8,69±1,398 слова при очень хорошем сне (χ2=12,264; df=5; p=0,015).</p></sec><sec><title>Заключение</title><p>Заключение. В популяционном исследовании установлена ассоциация между наличием НС и снижением когнитивных способностей (паттернов памяти, внимания и мышления) у лиц 25–44 лет.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивные функции</kwd><kwd>снижение когнитивных способностей</kwd><kwd>нарушение сна</kwd><kwd>паттерн</kwd><kwd>память</kwd><kwd>внимание</kwd><kwd>мышление</kwd><kwd>популяционные критерии</kwd><kwd>лица 25–44 лет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive functions</kwd><kwd>cognitive decline</kwd><kwd>sleep disturbance</kwd><kwd>pattern</kwd><kwd>memory</kwd><kwd>attention</kwd><kwd>executive functions</kwd><kwd>population criteria</kwd><kwd>individuals aged 25–44 years</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Li C, Ford ES, Zhao G, et al. 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