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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2024-6-36-44</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2416</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Features of mental state and reproductive function in dynamics inmentally ill women with infertility</article-title><trans-title-group xml:lang="ru"><trans-title>Характеристика психического состояния и репродуктивной функции в динамике у психически больных женщин с бесплодием</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5150-4765</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаевская</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaevskaya</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p> 305041, Курск, ул. К. Маркса, 3</p></bio><bio xml:lang="en"><p> 3, K. Marksa St., Kursk 305041</p></bio><email xlink:type="simple">nikolaevskayaao@kursksmu.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5202-1407</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тювина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyuvina</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> 119021, Москва, ул. Россолимо, 11, стр. 9 </p></bio><bio xml:lang="en"><p> 11, Rossolimo St., Build. 9, Moscow 119021 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2957-3956</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюльпин</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tulpin</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p> 119021, Москва, ул. Россолимо, 11, стр. 9 </p></bio><bio xml:lang="en"><p> 11, Rossolimo St., Build. 9, Moscow 119021 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3844-6062</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жиляева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhilyaeva</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p> 305041, Курск, ул. К. Маркса, 3</p></bio><bio xml:lang="en"><p>3, K. Marksa St., Kursk 305041 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра психиатрии и психосоматики и ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Psychiatry and Psychosomatics Kursk State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра психиатрии и наркологии Института клинической медицины им. Н.В. Склифосовского ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Psychiatry and Narcology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Кафедра внутренних болезней №2 ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of internal diseases №2, Kursk State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2024</year></pub-date><volume>16</volume><issue>6</issue><fpage>36</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nikolaevskaya A.O., Tyuvina N.A., Tulpin Y.G., Zhilyaeva Y.G., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Николаевская А.О., Тювина Н.А., Тюльпин Ю.Г., Жиляева Ю.А.</copyright-holder><copyright-holder xml:lang="en">Nikolaevskaya A.O., Tyuvina N.A., Tulpin Y.G., Zhilyaeva Y.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2416">https://nnp.ima-press.net/nnp/article/view/2416</self-uri><abstract><p>Women suffering from a mental disorder are faced with the problem of pregnancy and the realisation of their reproductive rights throughout their lives. The presence of a mental disorder largely determines the onset, course and outcome of pregnancy. A deterioration in mental health is often accompanied by an impairment of menstrual and reproductive function, and an improvement contributes to their recovery.</p><sec><title>Objective</title><p>Objective: to analyse individual indicators of reproductive function in women with various mental disorders and infertility in dynamics according to the follow-up data.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 120 women with various mental disorders and infertility, who were observed for 2 years by a psychiatrist and a gynaecologist on the background of treatment of the existing disorders.</p></sec><sec><title>Results</title><p>Results. In 70% of cases, mentally ill women have primary infertility, with idiopathic infertility predominating (63.3%), especially in the context of secondary infertility (77.8%; p&lt;0.05). Treatment of infertility by gynaecologists and mental disorders by psychiatrists leads to the normalization of the menstrual cycle and the onset of pregnancy. Pregnancy is usually accompanied by obstetric and somatic complications (fetal growth retardation and miscarriage, placental disorders, hypertension, oedema, lipid metabolism disorders, gestational diabetes mellitus). Reproductive function is impaired mostly in patients with schizophrenia and affective disorders, they account for 80.8% of observed infertility. Fertility is lowest in patients with paranoid schizophrenia: pregnancy occurred in 12.9% of patients, none of them gave birth. In schizoaffective disorder, 43.75% of women became pregnant, but only 20% gave birth. In bipolar affective disorder (BAD) type I, pregnancy occurred in 87.5% of patients (of which 57.1% resulted in a childbirth), in bipolar disorder type II – in 43.75% (of which 42.8% resulted in a childbirth), and in recurrent depressive disorder – in 60% (of which 50% resulted in a childbirth). In these disorders, the duration of infertility correlates with the duration of the disease (p&lt;0.05). In neurotic disorders, fertility suffers to a lesser extent: pregnancy with recovery or significant improvement of the mental condition occurred in 75–100% of cases, but only 66.7% of cases resulted in a child birth. Childbirth was mainly performed by caesarean section.</p></sec><sec><title>Conclusion</title><p>Conclusion. Reproductive function in mentally ill women depends largely on the type of mental disorder, the characteristics of its course, the efficacy of psychopharmacotherapy, the quality of remission and the degree of social and family adaptation, which must be taken into account in the diagnosis and treatment of infertility.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Женщины, страдающие психическими расстройствами, в течение жизни сталкиваются с проблемой наступления беременности и реализации своих репродуктивных прав. Наличие психического расстройства во многом определяет наступление, течение и исход беременности. Ухудшение психического состояния часто сопровождается нарушением менструальной и репродуктивной функции, а улучшение способствует ее восстановлению.</p><p>Цель исследования – проанализировать отдельные показатели репродуктивной функции у женщин с различными психическими расстройствами и бесплодием в динамике по данным катамнестического обследования.</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 120 женщин с различными психическими заболеваниями и бесплодием, которые наблюдались в течение 2 лет у психиатра и гинеколога с проведением лечения имеющихся расстройств.</p></sec><sec><title>Результаты</title><p>Результаты. У психически больных женщин в 70% случаев наблюдается первичное бесплодие, при этом преобладает идиопатическое бесплодие (63,3%), особенно в рамках вторичного бесплодия (77,8%; p&lt;0,05). Лечение бесплодия гинекологами и психических расстройств психиатрами приводит к нормализации менструального цикла и наступлению беременности. Беременность обычно протекает с акушерскими и соматическими осложнениями (задержка развития плода и невынашивание беременности, выкидыш, плацентарные нарушения, гипертензия, отеки, нарушения жирового обмена, гестационный сахарный диабет). Репродуктивная функция больше всего страдает у больных шизофренией и аффективными расстройствами: они составляют 80,8% от наблюдающихся с бесплодием. Самая низкая фертильность – у больных параноидной шизофренией: беременность наступила у 12,9% пациенток, ни одна не завершилась родами. При шизоаффективном расстройстве забеременели 43,75% женщин, но роды наступили только у 20%. При биполярном аффективном расстройстве (БАР) I типа беременность наступила у 87,5% пациенток (из них родами она завершилась у 57,1%), при БАР II типа – у 43,75% (из них родов – 42,8%), при рекуррентном депрессивном расстройстве – у 60% (из них родов – 50%). При этих расстройствах длительность бесплодия коррелирует с продолжительностью болезни (p&lt;0,05). При невротических расстройствах репродуктивная функция страдает в меньшей степени: беременности наступали при выздоровлении или значительном улучшении состояния в 75–100% случаев, но роды – только в 66,7%. Родоразрешение преимущественно проводилось путем кесарева сечения. Заключение. Репродуктивная функция у психически больных женщин во многом зависит от характера психического расстройства, особенностей его течения, эффективности психофармакотерапии, качества ремиссии, уровня социальной и семейной адаптации, что необходимо учитывать при диагностике и лечении бесплодия.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>психические расстройства</kwd><kwd>менструальная функция</kwd><kwd>бесплодие</kwd><kwd>беременность</kwd><kwd>репродуктивный статус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mental disorders</kwd><kwd>menstrual function</kwd><kwd>infertility</kwd><kwd>pregnancy</kwd><kwd>reproductive status</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Amnesty International USA. Stop Violence Against Women: Reproductive rights. SVAW. Amnesty International USA (2007). Available at: https://www.amnestyusa.org/issues/gendersexuality/sexual-reproductive-rights/</mixed-citation><mixed-citation xml:lang="en">Amnesty International USA. Stop Violence Against Women: Reproductive rights. SVAW. Amnesty International USA (2007). Available at: https://www.amnestyusa.org/issues/gendersexuality/sexual-reproductive-rights/</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Reproductive health (2017). WHO; World Health Organization. Retrieved September 6, 2021. Available at: http://www.who.int/topics/reproductive_health/en/</mixed-citation><mixed-citation xml:lang="en">WHO. Reproductive health (2017). WHO; World Health Organization. Retrieved September 6, 2021. Available at: http://www.who.int/topics/reproductive_health/en/</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Maybery D, Reupert AE. The number of parents who are patients attending adult psychiatric services. Curr Opin Psychiatry. 2018 Jul;31(4):358-62. doi: 10.1097/YCO.0000000000000427</mixed-citation><mixed-citation xml:lang="en">Maybery D, Reupert AE. The number of parents who are patients attending adult psychiatric services. Curr Opin Psychiatry. 2018 Jul;31(4):358-62. doi: 10.1097/YCO.0000000000000427</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Тювина НА, Николаевская АО. Роль психологических и психопатологических факторов в генезе идиопатического бесплодия. Психиатрия. 2022;20(1):110-9. doi: 10.30629/2618-6667-2022-20-1-110-119</mixed-citation><mixed-citation xml:lang="en">Tyuvina NA, Nikolaevskaya AO. The Role of Psychological and Psychopathological Factors in the Genesis of Idiopathic Infertility. Psikhiatriya. 2022;20(1):110-9. doi: 10.30629/2618-6667-2022-20-1-110-119 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Тювина НА, Николаевская АО, Балабанова ВВ, Ильченко КН. Сравнительная характеристика репродуктивной функции у психически здоровых и психически больных женщин с бесплодием. Гинекология. 2023;25(2):195-201. doi: 10.26442/20795696.2023.2.201838</mixed-citation><mixed-citation xml:lang="en">Tyuvina NA, Nikolayevskaya AO, Balabanova VV, Ilchenko KN. Comparative characteristics of reproductive function in mentally healthy and mentally ill women with infertility. Ginekologiya = Gynecology. 2023;25(2):195- 201. doi: 10.26442/20795696.2023.2.201838 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Иванец НН, Тювина НА, Воронина ЕО, Балабанова ВВ. Характеристика репродуктивной функции у женщин, страдающих рекуррентным депрессивным расстройством. Акушерство и гинекология. 2019;(3):92-7.</mixed-citation><mixed-citation xml:lang="en">Ivanets NN, Tyuvina NA, Voronina EO, Balabanova VV. Characteristics of reproductive function in women suffering from recurrent depressive disorder. Akusherstvo i ginekologiya = Obstetrics and gynecology. 2019;(3):92-7 (In Russ.). 7. Tyuvina NA, Voronina EO, Balabanova VV, Goncharova EM. The relationship and interaction of menstrual and generative function and depressive disorders in women. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2018;10(2):45- 51. doi: 10.14412/2074-2711-2018-2-45-51 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Тювина НА, Воронина ЕО, Балабанова ВВ, Гончарова ЕМ. Взаимосвязь и взаимовлияние менструально-генеративной функции и депрессивных расстройств у женщин. Неврология, нейропсихиатрия, психосоматика. 2018;10(2):45-51. doi: 10.14412/2074-2711-2018-2-45-51</mixed-citation><mixed-citation xml:lang="en">Tyuvina NA, Stolyarova AE, Voronina EO. Depression in women. Moscow: GEOTAR-Media; 2023 160 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Тювина НА, Столярова АЕ, Воронина ЕО. Депрессии у женщин. Москва: ГЭОТАР-Медиа; 2023. 160 с.</mixed-citation><mixed-citation xml:lang="en">Rasoulzadeh Bidgoli M, Latifnejad Roudsari R, Montazeri A. The effectiveness of a collaborative infertility counseling (CIC) on pregnancy outcome in women undergoing in vitro fertilization: a randomized trial. BMC Pregnancy Childbirth. 2020 Nov 25;20(1):728. doi: 10.1186/s12884-020-03417-6</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Rasoulzadeh Bidgoli M, Latifnejad Roudsari R, Montazeri A. The effectiveness of a collaborative infertility counseling (CIC) on pregnancy outcome in women undergoing in vitro fertilization: a randomized trial. BMC Pregnancy Childbirth. 2020 Nov 25;20(1):728. doi: 10.1186/s12884-020-03417-6</mixed-citation><mixed-citation xml:lang="en">Al-Worafi YM. Infertility Management in Developing Countries. In: Al-Worafi YM, ed. Handbook of Medical and Health Sciences in Developing Countries. Springer, Cham; 2024. doi: 10.1007/978-3-030-74786-2_93-1</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Worafi YM. Infertility Management in Developing Countries. In: Al-Worafi YM, ed. Handbook of Medical and Health Sciences in Developing Countries. Springer, Cham; 2024. doi: 10.1007/978-3-030-74786-2_93-1</mixed-citation><mixed-citation xml:lang="en">Rooney KL, Domar AD. The relationship between stress and infertility. Dialogues Clin Neurosci. 2018 Mar;20(1):41-7. doi: 10.31887/DCNS.2018.20.1/klrooney</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rooney KL, Domar AD. The relationship between stress and infertility. Dialogues Clin Neurosci. 2018 Mar;20(1):41-7. doi: 10.31887/DCNS.2018.20.1/klrooney</mixed-citation><mixed-citation xml:lang="en">Palomba S, Daolio J, Romeo S, et al. Lifestyle and fertility: the influence of stress and quality of life on female fertility. Reprod Biol Endocrinol. 2018 Dec 2;16(1):113. doi: 10.1186/s12958-018-0434-y</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Palomba S, Daolio J, Romeo S, et al. Lifestyle and fertility: the influence of stress and quality of life on female fertility. Reprod Biol Endocrinol. 2018 Dec 2;16(1):113. doi: 10.1186/s12958-018-0434-y</mixed-citation><mixed-citation xml:lang="en">Nikolaevskaya AO, Tyuvina NA, Balabanova VV. The influence of the mental state of women with infertility on their reproductive status. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2024;16(3):64-71. doi: 10.14412/2074-2711-2024-3-64-71 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Николаевская АО, Тювина НА, Балабанова ВВ. Влияние психического состояния женщин с бесплодием на их репродуктивный статус. Неврология, нейропсихиатрия, психосоматика. 2024;16(3):64-71. doi: 10.14412/2074-2711-2024-3-64-71</mixed-citation><mixed-citation xml:lang="en">Hope H, Parisi R, Ashcroft DM, et al. Fertility trends of women with serious mental illness in the United Kingdom 1992–2017: A primary care cohort study using the clinical practice research datalink. J Affect Disord. 2020 May 15;269:141-7. doi: 10.1016/j.jad.2020.03.037. Epub 2020 Mar 20.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hope H, Parisi R, Ashcroft DM, et al. Fertility trends of women with serious mental illness in the United Kingdom 1992–2017: A primary care cohort study using the clinical practice research datalink. J Affect Disord. 2020 May 15;269:141-7. doi: 10.1016/j.jad.2020.03.037. Epub 2020 Mar 20.</mixed-citation><mixed-citation xml:lang="en">Pierce M, Abel KM, Muwonge J Jr, et al. Prevalence of parental mental illness and association with socioeconomic adversity among children in Sweden between 2006 and 2016: a population-based cohort study. Lancet Public Health. 2020 Nov;5(11):e583- e591. doi: 10.1016/S2468-2667(20)30202-4</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Pierce M, Abel KM, Muwonge J Jr, et al. Prevalence of parental mental illness and association with socioeconomic adversity among children in Sweden between 2006 and 2016: a population-based cohort study. Lancet Public Health. 2020 Nov;5(11):e583- e591. doi: 10.1016/S2468-2667(20)30202-4</mixed-citation><mixed-citation xml:lang="en">Power RA, Kyaga S, Uher R, et al. Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings. JAMA Psychiatry. 2013 Jan;70(1):22-30. doi: 10.1001/jamapsychiatry.2013.268</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Power RA, Kyaga S, Uher R, et al. Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings. JAMA Psychiatry. 2013 Jan;70(1):22-30. doi: 10.1001/jamapsychiatry.2013.268</mixed-citation><mixed-citation xml:lang="en">Hope H, Pierce M, Johnstone ED, et al. The sexual and reproductive health of women with mental illness: a primary care registry study. Arch Womens Ment Health. 2022 Jun;25(3):585-93. doi: 10.1007/s00737-022-01214-y. Epub 2022 Apr 2.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hope H, Pierce M, Johnstone ED, et al. The sexual and reproductive health of women with mental illness: a primary care registry study. Arch Womens Ment Health. 2022 Jun;25(3):585-93. doi: 10.1007/s00737-022-01214-y. Epub 2022 Apr 2.</mixed-citation><mixed-citation xml:lang="en">Vigod SN, Seeman MV, Ray JG, et al. Temporal trends in general and age-specific fertility rates among women with schizophrenia (1996–2009): a population-based study in Ontario, Canada. Schizophr Res. 2012 Aug;139(1-3):169-75. doi: 10.1016/j.schres.2012.05.010. Epub 2012 Jun 1.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Vigod SN, Seeman MV, Ray JG, et al. Temporal trends in general and age-specific fertility rates among women with schizophrenia (1996–2009): a population-based study in Ontario, Canada. Schizophr Res. 2012 Aug;139(1-3):169-75. doi: 10.1016/j.schres.2012.05.010. Epub 2012 Jun 1.</mixed-citation><mixed-citation xml:lang="en">Petrova NN, Podolkhov EN, Gzgzyan AM, Niauri DA. Mental disorders and psychological characteristics of infertile women being treated with in vitro fertilization. Obozreniye psikhiatrii i meditsinskoy psikhologii imeni V.M. Bekhtereva. 2013;(2):42-9 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Петрова НН, Подольхов ЕН, Гзгзян АМ, Ниаури ДА. Психические расстройства и личностно-психологические особенности у женщин с бесплодием при лечении ЭКО. Обозрение психиатрии и медицинской психологии им. В.М. Бехтерева. 2013;(2):42-9.</mixed-citation><mixed-citation xml:lang="en">Ogawa M, Takamatsu K, Horiguchi F. Evaluation of factors associated with the anxiety and depression of female infertility patients. Biopsychosoc Med. 2011 Dec 23;5(1):15. doi: 10.1186/1751-0759-5-15</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Ogawa M, Takamatsu K, Horiguchi F. Evaluation of factors associated with the anxiety and depression of female infertility patients. Biopsychosoc Med. 2011 Dec 23;5(1):15. doi: 10.1186/1751-0759-5-15</mixed-citation><mixed-citation xml:lang="en">Hernandez-Diaz S, Smith CR, Shen A, et al; North American AED Pregnancy Registry; North American AED Pregnancy Registry. Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. doi: 10.1212/WNL.0b013e3182574f39. Epub 2012 May 2.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Hernandez-Diaz S, Smith CR, Shen A, et al; North American AED Pregnancy Registry; North American AED Pregnancy Registry. Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. doi: 10.1212/WNL.0b013e3182574f39. Epub 2012 May 2.</mixed-citation><mixed-citation xml:lang="en">Mazzone PP, Hogg KM, Weir CJ, et al. Comparison of Perinatal Outcomes for Women With and Without Epilepsy: A Systematic Review and Meta-analysis. JAMA Neurol. 2023 May 1;80(5):484-94. doi: 10.1001/jamaneurol.2023.0148. Erratum in: JAMA Neurol. 2024 Jun 1;81(6):663. doi: 10.1001/jamaneurol.2024.1248</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Mazzone PP, Hogg KM, Weir CJ, et al. Comparison of Perinatal Outcomes for Women With and Without Epilepsy: A Systematic Review and Meta-analysis. JAMA Neurol. 2023 May 1;80(5):484-94. doi: 10.1001/jamaneurol.2023.0148. Erratum in: JAMA Neurol. 2024 Jun 1;81(6):663. doi: 10.1001/jamaneurol.2024.1248</mixed-citation><mixed-citation xml:lang="en">Brutman VI. Violations of the instinct of procreation and reproductive behavior of women in connection with mental pathology. Voprosy psikhicheskogo zdorov’ya detey i podrostkov. 2017;17(S2):30-1 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Брутман ВИ. Нарушения инстинкта продолжения рода и репродуктивного поведения женщин в связи с психической патологией. Вопросы психического здоровья детей и подростков. 2017;17(S2):30-1.</mixed-citation><mixed-citation xml:lang="en">Magnus MC, Havdahl A, Morken NH, et al. Risk of miscarriage in women with psychiatric disorders. Br J Psychiatry. 2021 Sep;219(3):501-6. doi: 10.1192/bjp.2020.259</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Magnus MC, Havdahl A, Morken NH, et al. Risk of miscarriage in women with psychiatric disorders. Br J Psychiatry. 2021 Sep;219(3):501-6. doi: 10.1192/bjp.2020.259</mixed-citation><mixed-citation xml:lang="en">Nasyrova RF. State-of-art of the problem of study of mental health of women with reproductive system pathology. Sibirskiy vestnik psikhiatrii i narkologii. 2010;(1):52–55. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Насырова РФ. Современное состояние проблемы изучения психического здоровья женщин с патологией репродуктивной системы. Сибирский вестник психиатрии и наркологии. 2010;(1):52-5.</mixed-citation><mixed-citation xml:lang="en">Насырова РФ. Современное состояние проблемы изучения психического здоровья женщин с патологией репродуктивной системы. Сибирский вестник психиатрии и наркологии. 2010;(1):52-5.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
