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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2024-1S-23-30</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2377</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Diagnosis of chronic migraine and comorbid neurological disorders in real-life clinical practice</article-title><trans-title-group xml:lang="ru"><trans-title>Диагностика хронической мигрени и коморбидных неврологических расстройств в реальной клинической практике</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2752-4109</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вероника Александровна Головачева</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Veronika Aleksandrovna Golovacheva</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><email xlink:type="simple">xoxo.veronicka@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2845-7323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3286-3436</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таршилова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarshilova</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1570-5009</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115093, Москва, ул. Люсиновская, 39, стр. 2</p><p>115419, Москва, ул. Донская, 43</p></bio><bio xml:lang="en"><p>39, Lyusinovskaya St., Build. 2, Moscow 115093</p><p>343, Donskaya St., Build. 5, Moscow 115419</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра нервных болезней и нейрохирургии Института клинической медицины им. Н.В. Склифосовского ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Университетская клиника» ; 3ГБУЗ «Научно-практический психоневрологический центр им. З.П. Соловьева Департамента здравоохранения города Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>LLC “University Clinic” ; Z.P. Solovyev Research and Practical Psychoneurology Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2024</year></pub-date><volume>16</volume><issue>1S</issue><issue-title>Спецвыпуск: Головная боль</issue-title><fpage>23</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Golovacheva V.A., Golovacheva A.A., Tarshilova A.R., Osipova V.V., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Головачева В.А., Головачева А.А., Таршилова А.Р., Осипова В.В.</copyright-holder><copyright-holder xml:lang="en">Golovacheva V.A., Golovacheva A.A., Tarshilova A.R., Osipova V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2377">https://nnp.ima-press.net/nnp/article/view/2377</self-uri><abstract><p>Chronic migraine (CM) is a neurological disorder whose diagnosis requires not only knowledge of its diagnostic criteria, but also the physician's ability to differentiate between various forms of primary and secondary headache (HA), as well as to recognize comorbid neurological disorders that aggravate the course of CM. Timely and correct diagnosis of CM and comorbid disorders allows to prescribe effective treatment to a patient and convert the migraine from a chronic to an episodic form. The diagnostics of CM and comorbid neurological disorders has not been sufficiently investigated in our country, which formed the basis for this study.</p><sec><title>Objective</title><p>Objective: to evaluate the quality of diagnostics of CM and comorbid neurological disorders in real-life neurological practice.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 200 patients with CM (63 men and 137 women, mean age 33.1±7.1 years) admitted to A.Ya. Kozhevnikov Clinic of Nervous Diseases (CND) of Sechenov University, complaining of frequent headaches. They had previously been examined and treated by neurologists in other medical institutions on an outpatient and/or inpatient basis. A clinical interview was conducted with all patients to establish a diagnosis and analyze their previous treatment, and a psychometric test was performed to assess symptoms of anxiety and depression.</p></sec><sec><title>Results</title><p>Results. Only 6% of patients had been previously diagnosed with CM, the remaining 94% were incorrectly diagnosed with secondary HA. All patients had previously been prescribed additional examinations, mainly neuroimaging of the brain and ultrasound of the cerebral vessels, although there were no "red flags". None of the patients had been previously assessed for their emotional state, while almost all patients had high situational anxiety (n=190; 95%) and high personal anxiety (n = 180; 90%), there were symptoms of depression (n=190; 95%) of varying severity. Comorbid neurological disorders (medication overuse HA), insomnia, musculoskeletal pain etc.) were diagnosed in 91.5% of patients in CND and in only in 8% of patients in other medical centers.</p></sec><sec><title>Conclusion</title><p>Conclusion. In real-life clinical practice, CM and comorbid neurological disorders are inadequately diagnosed and excessive and unjustified additional examinations are prescribed.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Хроническая мигрень (ХМ) – неврологическое заболевание, диагностика которого требует не только знания его диагностических критериев, но и умения врача дифференцировать различные формы первичной и вторичной головной боли (ГБ), а также выявлять коморбидные неврологические расстройства, отягощающие течение ХМ. Своевременная правильная диагностика ХМ и коморбидных нарушений позволяет назначить пациенту эффективное лечение, трансформирующее мигрень из хронической в эпизодическую. Диагностика ХМ и коморбидных неврологических расстройств в нашей стране недостаточно изучена, что послужило основанием для проведения данного исследования.</p><p>Цель исследования – оценить качество установления диагноза ХМ и коморбидных неврологических расстройств в реальной неврологической практике.</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 200 пациентов с ХМ (63 мужчины и 137 женщин, средний возраст – 33,1±7,1 года), которые обратились за консультацией в Клинику нервных болезней им. А.Я. Кожевникова (КНБ) Сеченовского Университета с жалобой на частые ГБ, а ранее обследовались и получали лечение у неврологов в других медицинских учреждениях в амбулаторных и/или стационарных условиях. Со всеми пациентами проводилась клиническая беседа, направленная на установление диагноза и анализ предшествующего ведения пациентов, а также тестирование с помощью психометрических методик для оценки симптомов тревоги и депрессии.</p></sec><sec><title>Результаты</title><p>Результаты. Лишь 6% пациентов ранее был установлен диагноз ХМ, остальные 94% имели неправильные диагнозы вторичной ГБ. Всем пациентам ранее назначались дополнительные обследования, преимущественно методы нейровизуализации головного мозга, ультразвукового исследования сосудов головного мозга, даже при отсутствии «красных флагов». Ни у одного из пациентов ранее не оценивали эмоциональное состояние, при этом почти у всех пациентов была высокая ситуативная тревожность (n=190; 95%) и высокая личностная тревожность (n=180; 90%), присутствовали симптомы депрессии (n=190; 95%) разной степени выраженности. В КНБ коморбидные неврологические заболевания (лекарственно-индуцированная ГБ, инсомния, скелетно-мышечная боль и др.) были выявлены у 91,5%, в других медицинских учреждениях – лишь у 8% пациентов.</p></sec><sec><title>Заключение</title><p>Заключение. В реальной клинической практике наблюдается низкий уровень диагностики ХМ и коморбидных неврологических нарушений, а также чрезмерное, не обоснованное показаниями назначение дополнительных исследований.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая мигрень</kwd><kwd>лекарственно-индуцированная головная боль</kwd><kwd>коморбидные расстройства</kwd><kwd>диагностика</kwd><kwd>тревога</kwd><kwd>депрессия</kwd><kwd>дополнительные исследования</kwd><kwd>ошибочные диагнозы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic migraine</kwd><kwd>medication overuse headache</kwd><kwd>comorbid disorders</kwd><kwd>diagnostics</kwd><kwd>anxiety</kwd><kwd>depression</kwd><kwd>additional studies</kwd><kwd>misdiagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ayzenberg I, Katsarava Z, Sborowski A, et al. 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