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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2024-4-49-53</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2332</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Pituitary apoplexy with acute complete bilateral third nerve palsy and papillary involvement: A case report</article-title><trans-title-group xml:lang="ru"><trans-title>Pituitary apoplexy with acute complete bilateral third nerve palsy and papillary involvement: A case report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7106-9799</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Bahadoram</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Bahadoram</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><bio xml:lang="en"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5776-7945</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Sadrian</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Sadrian</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><bio xml:lang="en"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-5697-2961</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Sharififard</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharififard</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><bio xml:lang="en"><p>School of Medicine; Department of Neurology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7722-0165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Akade</surname><given-names>E.</given-names></name><name name-style="western" xml:lang="en"><surname>Akade</surname><given-names>E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>School of Medicine; Department of Medical Virology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><bio xml:lang="en"><p>School of Medicine; Department of Medical Virology</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9596-9882</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Rasras</surname><given-names>S.</given-names></name><name name-style="western" xml:lang="en"><surname>Rasras</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Saleh Rasras</p><p>School of Medicine; Department of Neurosurgery</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p><p>email address: salehrasras@ajums.ac.ir</p></bio><bio xml:lang="en"><p>School of Medicine; Department of Neurosurgery</p><p>Saleh Rasras</p><p>15794-61357; P.O. Box 159 Central Building Golestan Avenue; Ahvaz</p><p>email address: salehrasras@ajums.ac.ir</p></bio><email xlink:type="simple">etermitant@protonmail.ch</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ahvaz Jundishapur University of Medical Sciences</institution><country>Иран</country></aff><aff xml:lang="en"><institution>Ahvaz Jundishapur University of Medical Sciences</institution><country>Islamic Republic of Iran</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>08</month><year>2024</year></pub-date><volume>16</volume><issue>4</issue><fpage>49</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bahadoram M., Sadrian M., Sharififard M., Akade E., Rasras S., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Bahadoram M., Sadrian M., Sharififard M., Akade E., Rasras S.</copyright-holder><copyright-holder xml:lang="en">Bahadoram M., Sadrian M., Sharififard M., Akade E., Rasras S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2332">https://nnp.ima-press.net/nnp/article/view/2332</self-uri><abstract><p>   Pituitary apoplexy (PA) is a rare, potentially life-threatening condition primarily associated with pituitary adenomas. It presents with sudden, severe symptoms due to inadequate blood supply, bleeding, or tissue death in the pituitary gland. This case report describes a case of PA in a 40-year-old female, and reviews the recent literature surrounding the subject. The patient presented with complete bilateral third nerve palsy and dilated non-reactive pupils. Her initial symptoms included retroorbital headache, fever, and double vision, which rapidly progressed to oculomotor nerve palsy. MRI revealed hemorrhagic PA. High-dose steroids were initiated, leading to the resolution of ptosis. Additionally, surgical intervention was performed. PA typically affects older males with known adenomas, making this case unusual due to the patient's age, gender, and absence of prior adenoma history. Differentiating PA from other intracranial pathologies is crucial, and MRI plays a pivotal role in accurate diagnosis.</p></abstract><trans-abstract xml:lang="ru"><p>   Pituitary apoplexy (PA) is a rare, potentially life-threatening condition primarily associated with pituitary adenomas. It presents with sudden, severe symptoms due to inadequate blood supply, bleeding, or tissue death in the pituitary gland. This case report describes a case of PA in a 40-year-old female, and reviews the recent literature surrounding the subject. The patient presented with complete bilateral third nerve palsy and dilated non-reactive pupils. Her initial symptoms included retroorbital headache, fever, and double vision, which rapidly progressed to oculomotor nerve palsy. MRI revealed hemorrhagic PA. High-dose steroids were initiated, leading to the resolution of ptosis. Additionally, surgical intervention was performed. PA typically affects older males with known adenomas, making this case unusual due to the patient's age, gender, and absence of prior adenoma history. Differentiating PA from other intracranial pathologies is crucial, and MRI plays a pivotal role in accurate diagnosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>pituitary</kwd><kwd>apoplexy</kwd><kwd>oculomotor nerve palsy</kwd><kwd>headache</kwd><kwd>ptosis</kwd><kwd>transnasasl surgery</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pituitary</kwd><kwd>apoplexy</kwd><kwd>oculomotor nerve palsy</kwd><kwd>headache</kwd><kwd>ptosis</kwd><kwd>transnasasl surgery</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование не имело спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The investigation has not been sponsored</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mayol Del Valle M, De Jesus O. Pituitary Apoplexy. 2023 Aug 8. In: StatPearls [Internet]. 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