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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2024-3-38-43</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2277</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Rhythmic transcranial magnetic stimulation in the treatment of cervical dystonia and comorbid mental disorders</article-title><trans-title-group xml:lang="ru"><trans-title>Ритмическая транскраниальная магнитная стимуляция при цервикальной дистонии и коморбидных психических расстройствах</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4370-4249</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рагимова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ragimova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рагимова Айнур Алигейдаровна.</p><p>109028, Москва, Покровский бульвар, 11</p></bio><bio xml:lang="en"><p>Aynur A. Ragimova.</p><p>11, Pokrovsiy Blvd., Moscow 109028</p></bio><email xlink:type="simple">ragimovaasia@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2228-6316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петелин</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petelin</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovskaya St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9543-4041</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галяутдинова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Galyautdinova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovskaya St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8115-2668</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Толмачева</surname><given-names>В. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Tolmacheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovskaya St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1667-5355</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волель</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volel</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4; 115522, Москва, Каширское шоссе, 34</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovskaya St., Build. 4, Moscow 119991; 34, Kashirskoe Sh., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Национальный исследовательский университет “Высшая школа экономики”»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research University “Higher School of Economics”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет); ФГБНУ «Научный центр психического здоровья»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Mental Health Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>06</month><year>2024</year></pub-date><volume>16</volume><issue>3</issue><fpage>38</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ragimova A.A., Petelin D.S., Galyautdinova A.N., Tolmacheva V.A., Volel B.A., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Рагимова А.А., Петелин Д.С., Галяутдинова А.Н., Толмачева В.A., Волель Б.А.</copyright-holder><copyright-holder xml:lang="en">Ragimova A.A., Petelin D.S., Galyautdinova A.N., Tolmacheva V.A., Volel B.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2277">https://nnp.ima-press.net/nnp/article/view/2277</self-uri><abstract><p>Cervical dystonia (CD) is a common form of movement disorder with a high incidence of comorbid mental disorders. Rhythmic transcranial magnetic stimulation (rTMS) is effective in depression and other mental disorders, but its efficacy in CD with comorbid mental disorders has been poorly studied.</p><sec><title>Objective</title><p>Objective: to investigate the efficacy of rTMS in CD and comorbid mental disorders.</p></sec><sec><title>Material and methods</title><p>Material and methods. Seventeen patients with CD underwent a course of 10 rTMS sessions (protocol: 1 Hz, 600 pulses to the left primary motor cortex). The severity of mental disorders, quality of life and severity of cervical dystonia were assessed using the HADS, SF-36 and CDQ-24 scales.</p></sec><sec><title>Results</title><p>Results. After transcranial magnetic stimulation treatment, a significant reduction in anxiety (from 12.2±4.1 to 6.3±2.1 points; p&lt;0.01) and depression (from 8.4±3.7 to 5.2±3.2 points; p&lt;0.01) on the HADS scale were noted, and a significant improvement in both physical (from 37±15.2 to 45±17.3 points; p=0.017) and mental (from 31±11.2 to 38±9.6 points; p=0.008) quality of life components according to SF-36. The severity of CD according to CDQ-24 also decreased significantly (from 60.2±11.7 to 51±12.4 points; p=0.022), and there were improvements in the subscales of emotional well-being and social and family life.</p></sec><sec><title>Conclusion</title><p>Conclusion. The efficacy of rTMS in reducing the severity of both manifestations of CD and comorbid mental disorders was established.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цервикальная дистония (ЦД) является широко распространенной формой двигательных нарушений, при которой отмечается высокая частота коморбидных психических расстройств. Ритмическая транскраниальная магнитная стимуляция (рТМС) эффективна при депрессии и других психических расстройствах, но ее эффективность при ЦД с коморбидными психическими расстройствами мало изучена.</p><p>Цель исследования — изучение эффективности рТМС при ЦД и коморбидных психических расстройствах.</p><sec><title>Материал и методы</title><p>Материал и методы. Семнадцать пациентов с ЦД прошли курс из 10 сеансов рТМС (протокол: 1 Гц, 600 импульсов в область левой первичной моторной коры). Оценка тяжести психических расстройств, качества жизни и выраженности ЦД осуществлялась при помощи шкал HADS, SF-36, CDQ-24.</p></sec><sec><title>Результаты</title><p>Результаты. После курса ТМС были отмечены существенная редукция тревоги (с 12,2±4,1 до 6,3±2,1 балла; p&lt;0,01) и депрессии (с 8,4±3,7 до 5,2±3,2 балла; p&lt;0,01) по шкале HADS, значимое улучшение как физического (с 37±15,2 до 45±17,3 балла; p=0,017), так и психического (с 31±11,2 до 38±9,6 балла; p=0,008) компонентов качества жизни по SF-36. Выраженность тяжести ЦД по CDQ-24 также существенно уменьшилась (с 60,2±11,7 до 51±12,4 балла; p=0,022), причем улучшение было зарегистрировано по подшкалам эмоционального благополучия, а также социальной и семейной жизни.</p></sec><sec><title>Заключение</title><p>Заключение. Отмечена эффективность рТМС в отношении уменьшения выраженности как проявлений ЦД, так и коморбидных психических расстройств.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>цервикальная дистония</kwd><kwd>транскраниальная магнитная стимуляция</kwd><kwd>нелекарственные биологические методы терапии</kwd><kwd>немоторные симптомы</kwd><kwd>нейропсихиатрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cervical dystonia</kwd><kwd>transcranial magnetic stimulation</kwd><kwd>non-drug biological therapies</kwd><kwd>non-motor symptoms</kwd><kwd>neuropsychiatry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Shlomo Y, Camfield L, Warner T; ESDE collaborative group. What are the determinants of quality of life in people with cervical dystonia? 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