nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2024-2-69-75nnp-2234Research ArticleREVIEWSОБЗОРЫFunctional anatomy of the limbic system structures involved in the development of post-traumatic stress disorder: analysis of anatomical and clinical studiesФункциональная анатомия структур лимбической системы, вовлеченных в развитие посттравматического стрессового расстройства: анализ анатомо-клинических исследованийhttps://orcid.org/0000-0001-9532-9957НиколенкоВ. Н.NikolenkoV. N.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

vn.nikolenko@yandex.ruhttps://orcid.org/0009-0000-9227-6554ОсадчийА. С.OsadchiyA. S.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0009-0006-7521-809XЛобановаА. К.LobanovaA. K.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0009-0001-3927-2893ИсаковаТ. А.IsakovaT. A.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0009-0002-5200-5965ЖаровН. А.ZharovN. A.

127473, Москва, ул. Делегатская, 20, стр. 1

20, Delegatskaya St., Build. 1, Moscow 127473

https://orcid.org/0000-0003-2495-6923ЖароваН. В.ZharovaN. V.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow Medical University, Ministry of Health of Russia (Sechenov University)Russian FederationФГБОУ ВО «Российский университет медицины» Минздрава РоссииРоссияRussian University of Medicine, Ministry of Health of RussiaRussian Federation2024240420241626975Copyright © Nikolenko V.N., Osadchiy A.S., Lobanova A.K., Isakova T.A., Zharov N.A., Zharova N.V., 20242024Николенко В.Н., Осадчий А.С., Лобанова А.К., Исакова Т.А., Жаров Н.А., Жарова Н.В.Nikolenko V.N., Osadchiy A.S., Lobanova A.K., Isakova T.A., Zharov N.A., Zharova N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/2234

We present an analysis of anatomical and clinical studies investigating the morphological and functional characteristics of various structures of the limbic system involved in the development of post-traumatic stress disorder (PTSD). Understanding the structural organization and functional interactions of this system will provide new insights into the mechanisms underlying PTSD. The results of various morphological and clinical studies are considered, including information on the architecture and interconnections of the structures of the limbic system and their alteration by traumatic events. The generalized results provide new data on the role of the individual structures of the limbic system in the development of PTSD, enabling more accurate prediction of the development of PTSD and prompt appropriate measures to alleviate the course of this disorder

Представлен анализ анатомо-клинических исследований, в которых изучались морфофункциональные особенности различных структур лимбической системы, участвующих в развитии посттравматического стрессового расстройства (ПТСР). Понимание структурной организации и функциональных взаимодействий этой системы позволит по-новому взглянуть на лежащие в основе ПТСР механизмы. Рассмотрены результаты различных морфологических и клинических исследований, включая информацию об архитектуре и взаимосвязях структур лимбической системы, а также их изменениях, вызванных травмирующими событиями. Обобщенные результаты дают новые данные о роли отдельных структур лимбической системы в развитии ПТСР, которые позволят более точно прогнозировать развитие ПТСР и своевременно принимать соответствующие меры для облегчения течения этого расстройства.

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The authors declare that there are no conflicts of interest present.