nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2024-2-54-59nnp-2232Research ArticleREVIEWSОБЗОРЫAffective disorders in patients with epilepsy: primary process or consequence of paroxysmal activity?Аффективные расстройства у пациентов с эпилепсией: первичный процесс или следствие пароксизмальной активности?https://orcid.org/0000-0002-7333-6459ОсичкинаА. О.OsichkinaA. O.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

https://orcid.org/0000-0002-4658-2195КасьяновЕ. Д.KasyanovE. D.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

ohkasyan@yandex.ruhttps://orcid.org/0000-0002-5282-2036РукавишниковГ. В.RukavishnikovG. V.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

https://orcid.org/0000-0003-3635-5850ШоваН. И.ShovaN. I.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

https://orcid.org/0000-0002-7700-2704МихайловВ. А.MikhailovV. A.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

https://orcid.org/0000-0001-7910-9129МазоГ. Э.MazoG. E.

192019, Санкт-Петербург, ул. Бехтерева, 3

3, Bekhtereva St., St. Petersburg 192019

ФГБУ «Национальный медицинский исследовательский центр психиатрии и неврологии им. В.М. Бехтерева» Минздрава РоссииРоссияV.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, Ministry of Health of RussiaRussian Federation2024240420241625459Copyright © Osichkina A.O., Kasyanov E.D., Rukavishnikov G.V., Shova N.I., Mikhailov V.A., Mazo G.E., 20242024Осичкина А.О., Касьянов Е.Д., Рукавишников Г.В., Шова Н.И., Михайлов В.А., Мазо Г.Э.Osichkina A.O., Kasyanov E.D., Rukavishnikov G.V., Shova N.I., Mikhailov V.A., Mazo G.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/2232

The high prevalence of primary affective disorders in patients with epilepsy is beyond doubt. However, patients in this group are often identified as suffering from mood disorders that do not fulfil the criteria for primary mood disorders, such as recurrent depressive disorder and bipolar affective disorder. The aim of this paper is to analyze the classification and clinical picture of affective disorders in patients with epilepsy and differential diagnostic approaches to identify primary affective disorders and secondary affective disorders in epilepsy. A set of diagnostic signs for the differential assessment of affective disorders in patients with epilepsy is presented. Research of affective pathology in patients with epilepsy and the development of strategies for its successful treatment are still needed.

Высокая распространенность первичных аффективных расстройств у пациентов с эпилепсией не вызывает сомнений. Однако среди этой группы лиц зачастую выявляются пациенты, которые страдают аффективными нарушениями, не соответствующими критериям первичных аффективных расстройств, таких как рекуррентное депрессивное расстройство и биполярное аффективное расстройство. Целью данной работы является изучение вопросов систематики и клиники аффективных расстройств у пациентов с эпилепсией, а также дифференциально-диагностических подходов к выявлению первичных аффективных расстройств и вторичных аффективных нарушений при эпилепсии. Представлен набор диагностических признаков для дифференцированной оценки аффективных расстройств у пациентов с эпилепсией. Необходимы дальнейшие исследования аффективной патологии у пациентов с эпилепсией и разработка стратегий для их успешного лечения.

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The authors declare that there are no conflicts of interest present.