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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2024-1-82-86</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2187</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Acute cerebrovascular accidents in patients with new coronavirus infection COVID-19</article-title><trans-title-group xml:lang="ru"><trans-title>Острые нарушения мозгового кровообращения у пациентов с новой коронавирусной инфекцией COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6250-0762</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамалов</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamalov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><email xlink:type="simple">shamalovn@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1314-3388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климов</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimov</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5294-5706</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солдатов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Soldatov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4913-351X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiseleva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-7221-3312</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамалова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamalova</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0789-4823</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марская</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Marskaya</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1023-5490</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лянг</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyang</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997, Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>1, Ostrovityanova St., Build. 10, Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр мозга и нейротехнологий» Федерального медико-биологического агентства Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Brain and Neurotechnologies, Federal Biomedical Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>02</month><year>2024</year></pub-date><volume>16</volume><issue>1</issue><fpage>82</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Shamalov N.A., Klimov L.V., Soldatov M.A., Kiseleva T.V., Shamalova V.N., Marskaya N.A., Lyang O.V., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шамалов Н.А., Климов Л.В., Солдатов М.А., Киселева Т.В., Шамалова В.Н., Марская Н.А., Лянг О.В.</copyright-holder><copyright-holder xml:lang="en">Shamalov N.A., Klimov L.V., Soldatov M.A., Kiseleva T.V., Shamalova V.N., Marskaya N.A., Lyang O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2187">https://nnp.ima-press.net/nnp/article/view/2187</self-uri><abstract><p>The incidence of neurological complications in COVID-19 can reach 8–10% of all cases of new coronavirus infection; acute cerebrovascular accidents (ACA) dominate in their structure, which cause significant social and economic costs due to the high mortality and disability rates in this group of patients. The main pathophysiological mechanism leading to the development of ischemic cerebrovascular accidents (ischemic stroke, transient ischemic attack) is the phenomenon of hypercoagulation, which, together with the systemic inflammatory response to the viral infection, leads to the formation of macro- and microthrombi and the development of ischemic disorders of cerebral circulation. The ischemic stroke associated with COVID-19 is characterized by the onset at a younger age, the predominance of cryptogenic and cardioembolic pathogenetic variants, a more frequent occlusion of large cerebral vessels and thus a more pronounced clinical picture of the disease. The reserves for reducing mortality and disability in patients with cerebrovascular disease, especially stroke, during the spread of COVID-19 lie both in the prevention, treatment and rehabilitation of COVID-19 in patients at high risk of developing cardiovascular diseases and in ensuring specialized medical care for this category of patients.</p></abstract><trans-abstract xml:lang="ru"><p>Частота неврологических осложнений при COVID-19 может достигать 8–10% среди всех случаев заболевания новой коронавирусной инфекцией; в их структуре лидируют острые нарушения мозгового кровообращения (ОНМК), что влечет существенные социальные и экономические издержки вследствие высоких показателей летальности и инвалидизации в данной группе пациентов. Основным патофизиологическим механизмом, приводящим к развитию ОНМК по ишемическому типу (ишемический инсульт, транзиторная ишемическая атака), является феномен гиперкоагуляции, который, наряду с системным воспалительным ответом на вирусную инфекцию, приводит к образованию макро- и микротромбов и развитию ишемических нарушений мозгового кровообращения. Характерными для ассоциированного с COVID-19 ишемического инсульта признаками являются возникновение заболевания в более молодом возрасте, преобладание криптогенного и кардиоэмболического патогенетических вариантов, более частая окклюзия крупных мозговых сосудов и, как следствие, более выраженная клиническая картина болезни. Резервы по снижению смертности и инвалидизации у пациентов с цереброваскулярными заболеваниями, в частности с ОНМК, в период распространения COVID-19 заключаются как в профилактике, лечении COVID-19 и реабилитации у пациентов с высоким риском развития сердечно-сосудистых заболеваний, так и в обеспечении оказания специализированной медицинской помощи данной категории пациентов.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коронавирус SARS-CoV2</kwd><kwd>COVID-19</kwd><kwd>острое нарушение мозгового кровообращения</kwd><kwd>ишемический инсульт</kwd><kwd>геморрагический инсульт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronavirus SARS-CoV2</kwd><kwd>COVID-19</kwd><kwd>acute cerebrovascular accident</kwd><kwd>ischemic stroke</kwd><kwd>hemorrhagic stroke</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Всемирная организация здравоохранения. 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Epub 2020 May 12.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Временные методические рекомендации «Медицинская реабилитация при новой коронавирусной инфекции (COVID-19). Версия 3 (01.11.2022)» (утв. Минздравом России). 8. Неврологические нарушения и особенности медицинской реабилитации. Доступно по ссылке: https://www.consultant.ru/document/cons_doc_LAW_358669/8dda8df191569ec5e1a83da4ada25e7d0f29aa19/</mixed-citation><mixed-citation xml:lang="en">Temporary guidelines “Medical rehabilitation for new coronavirus infection (COVID-19). Version 3 (11/01/2022)" (approved by the Russian Ministry of Health).8. Neurological disorders and features of medical rehabilitation. Available at: https://www.consultant.ru/document/cons_doc_LAW_358669/8dda8df191569ec5e1a83da4ada25e7d0f29aa19/ (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Приказ Минздрава России от 31.07.2020 № 788н (ред. от 07.11.2022) «Об утверждении Порядка организации медицинской реабилитации взрослых» (Зарегистрировано в Минюсте России 25.09.2020 № 60039). Доступно по ссылке: https://www.consultant.ru/document/cons_doc_LAW_363102/251914c20e9de78b3ee8b2d5e0bf9dc53015020e/#dst100011</mixed-citation><mixed-citation xml:lang="en">Order of the Ministry of Health of Russia dated July 31, 2020 N 788n (as amended on November 7, 2022) “On approval of the Procedure for organizing medical rehabilitation of adults” (Registered with the Ministry of Justice of Russia on September 25, 2020 N 60039). Available at: https://www.consultant.ru/document/cons_doc_LAW_363102/251914c20e9de78b3ee8b2d5e0bf9dc53015020e/#dst100011 (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
