<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2013-2485</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Comorbidity of tics and epilepsy in children and adolescents</article-title><trans-title-group xml:lang="ru"><trans-title>Коморбидность тиков и эпилепсии у детей и подростков</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермоленко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolenko</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">ermola@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermakov</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">ermola@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">ermola@bk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бучнева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Buchneva</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">ermola@bk.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каликина</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalikina</surname><given-names>T. I.</given-names></name></name-alternatives><email xlink:type="simple">ermola@bk.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО «Воронежская государственная медицинская академия им. Н.Н. Бурденко» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Burdenko Voronezh State Medical Academy, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>МНИИ педиатрии и детской хирургии Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>БУЗ ВО Воронежская областная детская клиническая больница № 1, Воронеж</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh Regional Children’s Clinical Hospital One, Voronezh</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>УЗ ВО Воронежская областная детская клиническая больница № 1, Воронеж</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh Regional Children’s Clinical Hospital One, Voronezh</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2013</year></pub-date><volume>5</volume><issue>1S</issue><issue-title>Special issue "Epilepsy"</issue-title><fpage>29</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ermolenko N.A., Ermakov A.Y., Zakharova E.I., Buchneva I.A., Kalikina T.I., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Ермоленко Н.А., Ермаков А.Ю., Захарова Е.И., Бучнева И.А., Каликина Т.И.</copyright-holder><copyright-holder xml:lang="en">Ermolenko N.A., Ermakov A.Y., Zakharova E.I., Buchneva I.A., Kalikina T.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/217">https://nnp.ima-press.net/nnp/article/view/217</self-uri><abstract><p>Tics are the most common forms of hyperkinesis among children and adolescents, the etiology of which is not fully clear. A study has shown a high comorbidity of tic disorders and epilepsy, as evidenced by video-EEG monitoring. In patients with tics even in the absence of epileptic seizures, epileptiform activity is an adverse predictor and a determinant of the potential risk of comorbid epilepsy especially during neuroleptic therapy. Antiepileptic drugs are the drugs of choice to treat this category of patients.</p></abstract><trans-abstract xml:lang="ru"><p>Тики относятся к числу наиболее распространенных форм гиперкинезов среди детей и подростков, этиология которых до конца не ясна. Исследование показало высокую коморбидность тикозных расстройств (ТР) и эпилепсии, что подтверждается данными видео-ЭЭГ-мониторинга. Эпилептиформная активность у пациентов с ТР даже при отсутствии эпилептических приступов является неблагоприятным прогностическим фактором и определяет потенциальный риск присоединения эпилепсии, особенно на фоне терапии препаратами с нейролептической активностью. Лекарствами выбора у данной категории больных являются антиэпилептические препараты.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>тики</kwd><kwd>эпилепсия</kwd><kwd>ЭЭГ</kwd><kwd>вальпроат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>tics</kwd><kwd>epilepsy</kwd><kwd>EEG</kwd><kwd>valproate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
