nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-27112023-5-4-12nnp-2099Research ArticleEXPERT RECOMMENDATIONSРЕКОМЕНДАЦИИ ЭКСПЕРТОВNon-specific neck pain (cervicalgia). Guidelines of the Russian Society for the Study of Pain (RSSP)Неспецифическая боль в шее (цервикалгия). Рекомендации Российского общества по изучению боли (РОИБ)https://orcid.org/0000-0002-1992-7960ПарфеновВ. А.ParfenovV. A.

Владимир Анатольевич Парфенов

119991, Москва, ул. Трубецкая, 8, стр. 2

Vladimir Anatolyevich Parfenov

8, Trubetskaya St., Build. 2, Moscow 119991

vladimirparfenov@mail.ruhttps://orcid.org/0000-0002-8255-5645ЯхноН. Н.YakhnoN. N.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0000-0002-9406-5846КукушкинМ. Л.KukushkinM. L.

125315, Москва, ул. Балтийская, 8

8, Baltiyskaya St., Moscow 125315

https://orcid.org/0000-0003-3252-4311ДавыдовО. С.DavydovO. S.

125315, Москва, ул. Балтийская, 8

8, Baltiyskaya St., Moscow 125315

https://orcid.org/0000-0001-6542-1963ЧурюкановМ. В.ChuryukanovM. V.

119991, Москва, ул. Трубецкая, 8, стр. 2; 119991, Москва, Абрикосовский пер., 2

8, Trubetskaya St., Build. 2, Moscow 119991; 2, Abrikosovskiy Lane, Moscow 119991

https://orcid.org/0000-0002-2752-4109ГоловачеваВ. А.GolovachevaV. A.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0000-0002-6715-6021ЕвзиковГ. Ю.EvzikovG. Yu.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0000-0003-4950-144XИсайкинА. И.IsaikinA. I.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119991

https://orcid.org/0000-0001-9282-3319БахтадзеМ. А.BakhtadzeM. A.

117997, Москва, ул. Островитянова, 1

1, Ostrovityanova St., Moscow 117997

https://orcid.org/0000-0002-4191-7224МедведеваЛ. А.MedvedevaL. A.

119991, Москва, Абрикосовский пер., 2

2, Abrikosovskiy Lane, Moscow 119991

https://orcid.org/0000-0002-5590-9700КалинскийП. П.KalinskyP. P.

690002, Владивосток, просп. Острякова, 2

Ostryakova Prospect, Vladivostok 690002

https://orcid.org/0000-0003-1461-1761ШироковВ. А.ShirokovV. A.

620014, Екатеринбург, ул. Попова, 30

30, Popova St., Yekaterinburg 620014

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)Russian FederationФГБНУ «Научно-исследовательский институт общей патологии и патофизиологии»РоссияResearch Institute for General Pathology and PathophysiologyRussian FederationФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет); ФГБНУ «Российский научный центр хирургии им. акад. Б.В. Петровского»РоссияI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Academician B.V. Petrovsky Russian Research Center of SurgeryRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РоссииРоссияN.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaRussian FederationФГБНУ «Российский научный центр хирургии им. акад. Б.В. Петровского»РоссияAcademician B.V. Petrovsky Russian Research Center of SurgeryRussian FederationФГБОУ ВО «Тихоокеанский государственный медицинский университет» Минздрава России, ВладивостокРоссияPacific State Medical University, Ministry of Health of RussiaRussian FederationНПО «Клиника неврологии» ФБУН «Екатеринбургский медицинский-научный центр профилактики и охраны здоровья рабочих промышленных предприятий»РоссияResearch and Production Unit, Neurology Clinic, Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial WorkersRussian Federation202323102023155412Copyright © Parfenov V.A., Yakhno N.N., Kukushkin M.L., Davydov O.S., Churyukanov M.V., Golovacheva V.A., Evzikov G.Y., Isaikin A.I., Bakhtadze M.A., Medvedeva L.A., Kalinsky P.P., Shirokov V.A., 20232023Парфенов В.А., Яхно Н.Н., Кукушкин М.Л., Давыдов О.С., Чурюканов М.В., Головачева В.А., Евзиков Г.Ю., Исайкин А.И., Бахтадзе М.А., Медведева Л.А., Калинский П.П., Широков В.А.Parfenov V.A., Yakhno N.N., Kukushkin M.L., Davydov O.S., Churyukanov M.V., Golovacheva V.A., Evzikov G.Y., Isaikin A.I., Bakhtadze M.A., Medvedeva L.A., Kalinsky P.P., Shirokov V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/2099

Neck pain (NP) is one of the most common complaints of patients in outpatient practice and is predominantly non-specific (musculoskeletal) in nature. When examining a patient with NP, it is necessary to rule out a specific cause of the condition. The diagnosis of nonspecific NP (NNP) is based on a clinical examination that excludes signs of specific NP (“red flags”). If there are no signs of specific NP (“red flags”), early (in the first 4 weeks) magnetic resonance imaging is not indicated. It is recommended to inform the patient with NNP about the favorable prognosis of the disease, its risk factors, avoidance of prolonged excessive static and physical activity, incorrect (non-physiological) positions and postures, the effectiveness of therapeutic exercises (kinesiotherapy) and the advisability of maintaining physical activity. Non-steroidal anti-inflammatory drugs and muscle relaxants can be used to relieve NNP. For subacute and chronic NNP, kinesiotherapy, manual therapy in combination with psychological therapy methods (for depressive and anxiety disorders, pain catastrophizing, pain behavior), and antidepressants are recommended. Radiofrequency denervation may be effective for chronic NNP associated with cervical facet joint pathology. There are no convincing data on the efficacy of electrotherapy, ultrasound, traction, and wearing a cervical collar in the absence of orthopedic indications. For preventive treatment of NNP, kinesiotherapy and an educational program to avoid excessive static and physical activity, incorrect positions and postures are recommended. The issues of duration and frequency of therapeutic exercises for the treatment and prevention of NNP need further investigation.

Боль в шее (БШ) представляет собой одну из частых жалоб пациентов в амбулаторной практике и преимущественно имеет неспецифический (скелетно-мышечный) характер. При обследовании пациента с БШ (цервикалгией) необходимо исключить специфическую причину заболевания. Диагноз неспецифической БШ (НБШ) основывается на клиническом обследовании, исключении признаков специфической БШ («красных флажков»). Если отсутствуют признаки специфической БШ («красные флажки»), то раннее (в первые 4 нед) проведение магнитно-резонансной томографии не показано. Рекомендуется информировать пациента с НБШ о благоприятном прогнозе заболевания, факторах риска его развития, избегании длительных чрезмерных статических и физических нагрузок, неправильных (нефизиологичных) положений и поз, эффективности лечебных упражнений (кинезиотерапии), целесообразности сохранения физической активности. Для облегчения НБШ могут быть использованы нестероидные противовоспалительные препараты, миорелаксанты. При подострой и хронической НБШ рекомендуются кинезиотерапия, мануальная терапия всочетании спсихологическими методами терапии (при депрессивных итревожных расстройствах, феноменах катастрофизации боли, болевого поведения), антидепрессанты. При хронической НБШ, связанной с патологией шейных фасеточных суставов, может быть эффективна их радиочастотная денервация. Нет убедительных данных об эффективности методов электролечения, ультразвука, вытяжения и ношения шейного воротника, если нет ортопедических показаний. Для профилактики НБШ рекомендуются кинезиотерапия, образовательная программа по избеганию чрезмерных статических и физических нагрузок, неправильных положений ипоз. Вопросы длительности ичастоты лечебных упражнений для лечения ипрофилактики НБШ требуют дальнейшего изучения.

неспецифическая боль в шеецервикалгиянестероидные противовоспалительные препаратыкинезотерапиямануальная терапияиглорефлексотерапиякогнитивно-поведенческая терапиярадиочастотная денервация фасеточных суставовnon-specific neck paincervicalgianonsteroidal anti-inflammatory drugskinesiotherapymanual therapyacupuncturecognitive behavioral therapyradiofrequency denervation of facet jointsИсследование не имело спонсорской поддержкиThe investigation has not been sponsoredReferencesMurray CJ, Atkinson C, Bhalla K, et al.; U.S. Burden of Disease Collaborators. The state of US health, 1990–2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310(6):591-608. doi: 10.1001/jama.2013.13805Murray CJ, Atkinson C, Bhalla K, et al.; U.S. Burden of Disease Collaborators. The state of US health, 1990–2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310(6):591-608. doi: 10.1001/jama.2013.13805GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858. doi: 10.1016/S01406736(18)32279-7. Epub 2018 Nov 8. Erratum in: Lancet. 2019 Jun 22;393(10190):e44.GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858. doi: 10.1016/S01406736(18)32279-7. Epub 2018 Nov 8. Erratum in: Lancet. 2019 Jun 22;393(10190):e44.GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1204-22. doi: 10.1016/S0140-6736(20)30925-9. Erratum in: Lancet. 2020 Nov 14;396(10262):1562.GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1204-22. doi: 10.1016/S0140-6736(20)30925-9. Erratum in: Lancet. 2020 Nov 14;396(10262):1562.Kazeminasab S, Nejadghaderi SA, Amiri P, et al. Neck pain: global epidemiology, trends and risk factors. BMC Musculoskelet Disord. 2022 Jan 3;23(1):26. doi: 10.1186/s12891-02104957-4Kazeminasab S, Nejadghaderi SA, Amiri P, et al. Neck pain: global epidemiology, trends and risk factors. BMC Musculoskelet Disord. 2022 Jan 3;23(1):26. doi: 10.1186/s12891-02104957-4Safiri S, Kolahi AA, Hoy D, et al. Global, regional, and national burden of neck pain in the general population, 1990–2017: systematic analysis of the Global Burden of Disease Study 2017. BMJ. 2020 Mar 26;368:m791. doi: 10.1136/bmj.m791Safiri S, Kolahi AA, Hoy D, et al. Global, regional, and national burden of neck pain in the general population, 1990–2017: systematic analysis of the Global Burden of Disease Study 2017. BMJ. 2020 Mar 26;368:m791. doi: 10.1136/bmj.m791Cohen SP. Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc. 2015 Feb;90(2):284-99. doi: 10.1016/j.mayocp.2014.09.008Cohen SP. Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc. 2015 Feb;90(2):284-99. doi: 10.1016/j.mayocp.2014.09.008Hurwitz EL, Randhawa K, Yu H, et al. The Global Spine Care Initiative: a summary of the global burden of low back and neck pain studies. Eur Spine J. 2018 Sep;27(Suppl 6):796801. doi: 10.1007/s00586-017-5432-9. Epub 2018 Feb 26.Hurwitz EL, Randhawa K, Yu H, et al. The Global Spine Care Initiative: a summary of the global burden of low back and neck pain studies. Eur Spine J. 2018 Sep;27(Suppl 6):796801. doi: 10.1007/s00586-017-5432-9. Epub 2018 Feb 26.Guzman J, Haldeman S, Carroll LJ, et al; Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Clinical practice implications of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders: from concepts and findings to recommendations. Spine (Phila Pa 1976). 2008 Feb 15;33(4 Suppl):S199-213. doi: 10.1097/BRS.0b013e3181644641Guzman J, Haldeman S, Carroll LJ, et al; Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Clinical practice implications of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders: from concepts and findings to recommendations. Spine (Phila Pa 1976). 2008 Feb 15;33(4 Suppl):S199-213. doi: 10.1097/BRS.0b013e3181644641Haldeman S, Carroll L, Cassidy JD, et al. The Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Eur Spine J. 2008;17(Suppl 1):5-7. doi: 10.1007/s00586-008-0619-8Haldeman S, Carroll L, Cassidy JD, et al. The Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Eur Spine J. 2008;17(Suppl 1):5-7. doi: 10.1007/s00586-008-0619-8Cohen SP, Hooten WM. Advances in the diagnosis and management of neck pain. BMJ. 2017 Aug 14;358:j3221. doi: 10.1136/bmj.j3221Cohen SP, Hooten WM. Advances in the diagnosis and management of neck pain. BMJ. 2017 Aug 14;358:j3221. doi: 10.1136/bmj.j3221Misailidou V, Malliou P, Beneka A, et al. Assessment of patients with neck pain: a review of definitions, selection criteria, and measurement tools. J Chiropr Med. 2010 Jun;9(2):49-59. doi: 10.1016/j.jcm.2010.03.002Misailidou V, Malliou P, Beneka A, et al. Assessment of patients with neck pain: a review of definitions, selection criteria, and measurement tools. J Chiropr Med. 2010 Jun;9(2):49-59. doi: 10.1016/j.jcm.2010.03.002Treede RD, Rief W, Barke A, et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain. 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384Treede RD, Rief W, Barke A, et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain. 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384Cote P, Wong JJ, Sutton D, et al. Management of neck pain and associated disorders: A clinical practice guideline from the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Eur Spine J. 2016 Jul;25(7):2000-22. doi: 10.1007/s00586-016-4467-7. Epub 2016 Mar 16.Cote P, Wong JJ, Sutton D, et al. Management of neck pain and associated disorders: A clinical practice guideline from the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Eur Spine J. 2016 Jul;25(7):2000-22. doi: 10.1007/s00586-016-4467-7. Epub 2016 Mar 16.Monticone M, Iovine R, de Sena G, et al; Italian Society of Physical and Rehabilitation Medicine (SIMFER). The Italian Society of Physical and Rehabilitation Medicine (SIMFER) recommendations for neck pain. G Ital Med Lav Ergon. 2013 Jan-Mar;35(1):3650. Available from: https://pubmed.ncbi.nlm.nih.gov/23798233/Monticone M, Iovine R, de Sena G, et al; Italian Society of Physical and Rehabilitation Medicine (SIMFER). The Italian Society of Physical and Rehabilitation Medicine (SIMFER) recommendations for neck pain. G Ital Med Lav Ergon. 2013 Jan-Mar;35(1):3650. Available from: https://pubmed.ncbi.nlm.nih.gov/23798233/Bier JD, Scholten-Peeters WGM, Staal JB, et al. Clinical Practice Guideline for Physical Therapy Assessment and Treatment in Patients With Nonspecific Neck Pain. Phys Ther. 2018 Mar 1;98(3):162-71. doi: 10.1093/ptj/pzx118Bier JD, Scholten-Peeters WGM, Staal JB, et al. Clinical Practice Guideline for Physical Therapy Assessment and Treatment in Patients With Nonspecific Neck Pain. Phys Ther. 2018 Mar 1;98(3):162-71. doi: 10.1093/ptj/pzx118Lin I, Wiles L, Waller R, et al. What does best practice care for musculoskeletal pain look like? Eleven consistent recommendations from high-quality clinical practice guidelines: systematic review. Br J Sports Med. 2020 Jan;54(2):79-86. doi: 10.1136/bjsports-2018099878. Epub 2019 Mar 2.Lin I, Wiles L, Waller R, et al. What does best practice care for musculoskeletal pain look like? Eleven consistent recommendations from high-quality clinical practice guidelines: systematic review. Br J Sports Med. 2020 Jan;54(2):79-86. doi: 10.1136/bjsports-2018099878. Epub 2019 Mar 2.Corp N, Mansell G, Stynes S, et al. Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. Eur J Pain. 2021 Feb;25(2):275-95. doi: 10.1002/ejp.1679. Epub 2020 Nov 12.Corp N, Mansell G, Stynes S, et al. Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. Eur J Pain. 2021 Feb;25(2):275-95. doi: 10.1002/ejp.1679. Epub 2020 Nov 12.Парфенов ВА, Яхно НН, Кукушкин МЛ и др. Острая неспецифическая (скелетномышечная) поясничная боль. Рекомендации Российского общества по изучению боли (РОИБ). Неврология, нейропсихиатрия, психосоматика. 2018;10(2):4-11. doi: 10.14412/2074-2711-2018-2-4-11Parfenov VA, Yakhno NN, Kukushkin ML, et al. Acute nonspecific (musculoskeletal) low back pain Guidelines of the Russian Society for the Study of Pain (RSSP). Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2018;10(2):411. doi: 10.14412/2074-2711-2018-2-4-11 (In Russ.).Парфенов ВА, Яхно НН, Давыдов ОС и др. Хроническая неспецифическая (скелетно-мышечная) поясничная боль. Рекомендации Российского общества по изучению боли (РОИБ). Неврология, нейропсихиатрия, психосоматика. 2019;11(2S):7-16. doi: 10.14412/2074-2711-2019-2S-7-16Parfenov VA, Yakhno NN, Davydov OS, et al. Chronic nonspecific (musculoskeletal) low back pain. Guidelines of the Russian Society for the Study of Pain (RSSP). Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2S):716. doi: 10.14412/2074-2711-2019-2S-7-16 (In Russ.).Парфенов ВА, Яхно НН, Давыдов ОС и др. Дискогенная пояснично-крестцовая радикулопатия. Рекомендации Российского общества по изучению боли (РОИБ). Неврология, нейропсихиатрия, психосоматика. 2020;12(4):15-24. doi: 10.14412/20742711-2020-4-15-24Parfenov VA, Yakhno NN, Davydov OS, et al. Discogenic lumbosacral radiculopathy. Guidelines of the Russian Society for the Study of Pain (RSSP). Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2020;12(4):15-24. doi: 10.14412/2074-2711-2020-4-15-24 (In Russ.).Blanpied PR, Gross AR, Elliott JM, et al. Neck Pain: Revision 2017. J Orthop Sports Phys Ther. 2017 Jul;47(7):A1-A83. doi: 10.2519/jospt.2017.0302Blanpied PR, Gross AR, Elliott JM, et al. Neck Pain: Revision 2017. J Orthop Sports Phys Ther. 2017 Jul;47(7):A1-A83. doi: 10.2519/jospt.2017.0302Jahre H, Grotle M, Smedbraten K, et al. Risk factors for non-specific neck pain in young adults. A systematic review. BMC Musculoskelet Disord. 2020 Jun 9;21(1):366. doi: 10.1186/s12891-020-03379-yJahre H, Grotle M, Smedbraten K, et al. Risk factors for non-specific neck pain in young adults. A systematic review. BMC Musculoskelet Disord. 2020 Jun 9;21(1):366. doi: 10.1186/s12891-020-03379-yYang H, Hitchcock E, Haldeman S, et al. Workplace psychosocial and organizational factors for neck pain in workers in the United States. Am J Ind Med. 2016 Jul;59(7):549-60. doi: 10.1002/ajim.22602. Epub 2016 May 17.Yang H, Hitchcock E, Haldeman S, et al. Workplace psychosocial and organizational factors for neck pain in workers in the United States. Am J Ind Med. 2016 Jul;59(7):549-60. doi: 10.1002/ajim.22602. Epub 2016 May 17.Kim R, Wiest C, Clark K, et al. Identifying risk factors for first-episode neck pain: A systematic review. Musculoskelet Sci Pract. 2018 Feb;33:77-83. doi: 10.1016/j.msksp.2017.11.007. Epub 2017 Nov 22.Kim R, Wiest C, Clark K, et al. Identifying risk factors for first-episode neck pain: A systematic review. Musculoskelet Sci Pract. 2018 Feb;33:77-83. doi: 10.1016/j.msksp.2017.11.007. Epub 2017 Nov 22.Gao Y, Chen Z, Chen S, et al. Risk factors for neck pain in college students: a systematic review and meta-analysis. BMC Public Health. 2023 Aug 8;23(1):1502. doi: 10.1186/s12889023-16212-7Gao Y, Chen Z, Chen S, et al. Risk factors for neck pain in college students: a systematic review and meta-analysis. BMC Public Health. 2023 Aug 8;23(1):1502. doi: 10.1186/s12889023-16212-7Kamper SJ, Apeldoorn AT, Chiarotto A, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain. Cochrane Database Syst Rev. 2014 Sep 2;(9):CD000963. doi: 10.1002/14651858.CD000963.pub3Kamper SJ, Apeldoorn AT, Chiarotto A, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain. Cochrane Database Syst Rev. 2014 Sep 2;(9):CD000963. doi: 10.1002/14651858.CD000963.pub3Liu F, Fang T, Zhou F, et al. Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China. Pain Res Manag. 2018 Sep 25;2018:3259431. doi: 10.1155/2018/3259431. eCollection 2018.Liu F, Fang T, Zhou F, et al. Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China. Pain Res Manag. 2018 Sep 25;2018:3259431. doi: 10.1155/2018/3259431. eCollection 2018.Vasseljen O, Woodhouse A, Bjorngaard JH, Leivseth L. Natural course of acute neck and low back pain in the general population: the HUNT study. Pain. 2013 Aug;154(8):123744. doi: 10.1016/j.pain.2013.03.032. Epub 2013 Apr 2.Vasseljen O, Woodhouse A, Bjorngaard JH, Leivseth L. Natural course of acute neck and low back pain in the general population: the HUNT study. Pain. 2013 Aug;154(8):123744. doi: 10.1016/j.pain.2013.03.032. Epub 2013 Apr 2.Бахтадзе МА, Вернон Г, Кузьминов КО и др. Индекс ограничения жизнедеятельности из-за боли в шее: оценка надежности русской версии. Российский журнал боли. 2013;(2):6-13. Доступно по ссылке: https://painrussia.ru/pdf/web/viewer.html?file=/russian-Journal-of-Pain/39 13.pdfBakhtadze MA, Vernon H, Kuz'minov KO, et al. The Neck Disability Index: reliability of the Russian version. Rossiyskiy zhurnal boli. 2013;(2):6-13. Available from: https://painrussia.ru/pdf/web/viewer.html?file=/russianJournal-of-Pain/39 13.pdf (In Russ.).Бахтадзе МА, Проскуряков КВ, Лусникова ИВ. Индекс ограничения жизнедеятельности из-за боли в шее: модификация русскоязычной версии опросника. Российский журнал боли. 2020;18(3):54-60. Доступно по ссылке: https://painrussia.ru/pdf/web/viewer.html?file=/russian-Journal-of-Pain/03 20.pdfBakhtadze MA, Proskuryakov KV, Lusnikova IV. The Neck Disability Index: modification of the Russian-language version of the questionnaire. Rossiyskiy zhurnal boli. 2020;18(3):54-60. Available from: https://painrussia.ru/pdf/web/viewer.html?file=/russian-Journal-of-Pain/03 20.pdf (In Russ.).Matsumoto M, Fujimura Y, Suzuki N, et al. MRI of cervical intervertebral discs in asymptomatic subjects. J Bone Joint Surg Br. 1998 Jan;80(1):19-24. doi: 10.1302/0301620x.80b1.7929Matsumoto M, Fujimura Y, Suzuki N, et al. MRI of cervical intervertebral discs in asymptomatic subjects. J Bone Joint Surg Br. 1998 Jan;80(1):19-24. doi: 10.1302/0301620x.80b1.7929Jones CM, Shaheed CA, Ferreira GE, et al. Advice and education provide small short-term improvements in pain and disability in people with non-specific spinal pain: a systematic review. J Physiother. 2021 Oct;67(4):263-70. doi: 10.1016/j.jphys.2021.08.014. Epub 2021 Sep 10.Jones CM, Shaheed CA, Ferreira GE, et al. Advice and education provide small short-term improvements in pain and disability in people with non-specific spinal pain: a systematic review. J Physiother. 2021 Oct;67(4):263-70. doi: 10.1016/j.jphys.2021.08.014. Epub 2021 Sep 10.Sun E, Moshfegh J, Rishel CA, et al. Association of Early Physical Therapy With Long-term Opioid Use Among OpioidNaive Patients With Musculoskeletal Pain. JAMA Netw Open. 2018 Dec 7;1(8):e185909. doi: 10.1001/jamanetworkopen.2018.5909Sun E, Moshfegh J, Rishel CA, et al. Association of Early Physical Therapy With Long-term Opioid Use Among OpioidNaive Patients With Musculoskeletal Pain. JAMA Netw Open. 2018 Dec 7;1(8):e185909. doi: 10.1001/jamanetworkopen.2018.5909Gross A, Kay TM, Paquin JP, et al; Cervical Overview Group. Exercises for mechanical neck disorders. Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD004250. doi: 10.1002/14651858.CD004250.pub5Gross A, Kay TM, Paquin JP, et al; Cervical Overview Group. Exercises for mechanical neck disorders. Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD004250. doi: 10.1002/14651858.CD004250.pub5Chen X, Coombes BK, Sjogaard G, et al. Workplace-Based Interventions for Neck Pain in Office Workers: Systematic Review and Meta-Analysis. Phys Ther. 2018 Jan 1;98(1):40-62. doi: 10.1093/ptj/pzx101Chen X, Coombes BK, Sjogaard G, et al. Workplace-Based Interventions for Neck Pain in Office Workers: Systematic Review and Meta-Analysis. Phys Ther. 2018 Jan 1;98(1):40-62. doi: 10.1093/ptj/pzx101Louw S, Makwela S, Manas L, et al. Effectiveness of exercise in office workers with neck pain: A systematic review and meta-analysis. S Afr J Physiother. 2017 Nov 28;73(1):392. doi: 10.4102/sajp.v73i1.392Louw S, Makwela S, Manas L, et al. Effectiveness of exercise in office workers with neck pain: A systematic review and meta-analysis. S Afr J Physiother. 2017 Nov 28;73(1):392. doi: 10.4102/sajp.v73i1.392Price J, Rushton A, Tyros I, et al. Effectiveness and optimal dosage of exercise training for chronic non-specific neck pain: A systematic review with a narrative synthesis. PLoS One. 2020 Jun 10;15(6):e0234511. doi: 10.1371/journal.pone.0234511Price J, Rushton A, Tyros I, et al. Effectiveness and optimal dosage of exercise training for chronic non-specific neck pain: A systematic review with a narrative synthesis. PLoS One. 2020 Jun 10;15(6):e0234511. doi: 10.1371/journal.pone.0234511Tersa-Miralles C, Bravo C, Bellon F, et al. Effectiveness of workplace exercise interventions in the treatment of musculoskeletal disorders in office workers: a systematic review. BMJ Open. 2022 Jan 31;12(1):e054288. doi: 10.1136/bmjopen-2021-054288Tersa-Miralles C, Bravo C, Bellon F, et al. Effectiveness of workplace exercise interventions in the treatment of musculoskeletal disorders in office workers: a systematic review. BMJ Open. 2022 Jan 31;12(1):e054288. doi: 10.1136/bmjopen-2021-054288Nelson NL. Kinesio taping for chronic low back pain: A systematic review. J Bodyw Mov Ther. 2016 Jul;20(3):672-81. doi: 10.1016/j.jbmt.2016.04.018. Epub 2016 Apr 27.Nelson NL. Kinesio taping for chronic low back pain: A systematic review. J Bodyw Mov Ther. 2016 Jul;20(3):672-81. doi: 10.1016/j.jbmt.2016.04.018. Epub 2016 Apr 27.Machado GC, Maher CG, Ferreira PH, et al. Non-steroidal anti-inflammatory drugs for spinal pain: a systematic review and meta-analysis. Ann Rheum Dis. 2017 Jul;76(7):1269-78. doi: 10.1136/annrheumdis2016-210597. Epub 2017 Feb 2.Machado GC, Maher CG, Ferreira PH, et al. Non-steroidal anti-inflammatory drugs for spinal pain: a systematic review and meta-analysis. Ann Rheum Dis. 2017 Jul;76(7):1269-78. doi: 10.1136/annrheumdis2016-210597. Epub 2017 Feb 2.Pinto RZ, Maher CG, Ferreira ML, et al. Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis. BMJ. 2012 Feb 13;344:e497. doi: 10.1136/bmj.e497Pinto RZ, Maher CG, Ferreira ML, et al. Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis. BMJ. 2012 Feb 13;344:e497. doi: 10.1136/bmj.e497Rasmussen-Barr E, Held U, Grooten WJA, et al. Nonsteroidal Anti-inflammatory Drugs for Sciatica: An Updated Cochrane Review. Spine (Phila Pa 1976). 2017 Apr 15;42(8):58694. doi: 10.1097/BRS.0000000000002092Rasmussen-Barr E, Held U, Grooten WJA, et al. Nonsteroidal Anti-inflammatory Drugs for Sciatica: An Updated Cochrane Review. Spine (Phila Pa 1976). 2017 Apr 15;42(8):58694. doi: 10.1097/BRS.0000000000002092Каратеев АЕ, Насонов ЕЛ, Ивашкин ВТ и др.; Ассоциация ревматологов России, Российское общество по изучению боли, Российская гастроэнтерологическая ассоциация, Российское научное медицинское общество терапевтов, Ассоциация травматологов-ортопедов России, Российская ассоциация паллиативной медицины. Рациональное использование нестероидных противовоспалительных препаратов. Клинические рекомендации. Научно-практическая ревматология. 2018;56(Прил. 1):1-29. doi: 10.14412/1995-4484-2018-1-29Karateev AE, Nasonov EL, Ivashkin VT, et al; Association of Rheumatologists of Russia, Russian Society for the Study of Pain, Russian Gastroenterology Association, Russian Scientific Medical Society of Therapists, Association of Traumatologists and Orthopedists of Russia, Russian Association of Palliative Medicine. Rational use of nonsteroidal anti-inflammatory drugs. Clinical guidelines. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2018;56(Suppl. 1):1-29. doi: 10.14412/19954484-2018-1-29 (In Russ.).Oliveira CB, Maher CG, Pinto RZ, et al. Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview. Eur Spine J. 2018 Nov;27(11):2791-803. doi: 10.1007/s00586018-5673-2. Epub 2018 Jul 3.Oliveira CB, Maher CG, Pinto RZ, et al. Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview. Eur Spine J. 2018 Nov;27(11):2791-803. doi: 10.1007/s00586018-5673-2. Epub 2018 Jul 3.Machado GC, Maher CG, Ferreira PH, et al. Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials. BMJ. 2015 Mar 31;350:h1225. doi: 10.1136/bmj.h1225Machado GC, Maher CG, Ferreira PH, et al. Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials. BMJ. 2015 Mar 31;350:h1225. doi: 10.1136/bmj.h1225Calderon-Ospina CA, Nava-Mesa MO, Arbelaez Ariza CE. Effect of combined diclofenac and B vitamins (thiamine, pyridox ine, and cyanocobalamin) for low back pain management: systematic review and metaanalysis. Pain Med. 2020;21(4):766-81. doi: 10.1093/pm/pnz216Calderon-Ospina CA, Nava-Mesa MO, Arbelaez Ariza CE. Effect of combined diclofenac and B vitamins (thiamine, pyridox ine, and cyanocobalamin) for low back pain management: systematic review and metaanalysis. Pain Med. 2020;21(4):766-81. doi: 10.1093/pm/pnz216Castellini G, Pillastrini P, Vanti C, et al. Some conservative interventions are more effective than others for people with chronic non-specific neck pain: a systematic review and network meta-analysis. J Physiother. 2022 Oct;68(4):244-54. doi: 10.1016/j.jphys.2022.09.007. Epub 2022 Oct 17.Castellini G, Pillastrini P, Vanti C, et al. Some conservative interventions are more effective than others for people with chronic non-specific neck pain: a systematic review and network meta-analysis. J Physiother. 2022 Oct;68(4):244-54. doi: 10.1016/j.jphys.2022.09.007. Epub 2022 Oct 17.Bronfort G, Evans R, Anderson AV, et al. Spinal manipulation, medication, or home exercise with advice for acute and subacute neck pain: a randomized trial. Ann Intern Med. 2012 Jan 3;156(1 Pt 1):1-10. doi: 10.7326/00034819-156-1-201201030-00002Bronfort G, Evans R, Anderson AV, et al. Spinal manipulation, medication, or home exercise with advice for acute and subacute neck pain: a randomized trial. Ann Intern Med. 2012 Jan 3;156(1 Pt 1):1-10. doi: 10.7326/00034819-156-1-201201030-00002Gross A, Langevin P, Burnie SJ, et al. Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment. Cochrane Database Syst Rev. 2015 Sep 23;(9):CD004249. doi: 10.1002/14651858.CD004249.pub4Gross A, Langevin P, Burnie SJ, et al. Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment. Cochrane Database Syst Rev. 2015 Sep 23;(9):CD004249. doi: 10.1002/14651858.CD004249.pub4Minnucci S, Innocenti T, Salvioli S, et al. Benefits and Harms of Spinal Manipulative Therapy for Treating Recent and Persistent Nonspecific Neck Pain: A Systematic Review With Meta-analysis. J Orthop Sports Phys Ther. 2023 Sep;0(9):510-28. doi: 10.2519/jospt.2023.11708Minnucci S, Innocenti T, Salvioli S, et al. Benefits and Harms of Spinal Manipulative Therapy for Treating Recent and Persistent Nonspecific Neck Pain: A Systematic Review With Meta-analysis. J Orthop Sports Phys Ther. 2023 Sep;0(9):510-28. doi: 10.2519/jospt.2023.11708National Guideline Centre (UK). Evidence review for manual therapy for chronic primary pain: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain: Evidence review I. London: National Institute for Health and Care Excellence (NICE); 2021 Apr. Available from: https://pubmed.ncbi.nlm.nih.gov/33939359/National Guideline Centre (UK). Evidence review for manual therapy for chronic primary pain: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain: Evidence review I. London: National Institute for Health and Care Excellence (NICE); 2021 Apr. Available from: https://pubmed.ncbi.nlm.nih.gov/33939359/Manchikanti L, Knezevic NN, Knezevic E, et al. A Systematic Review and Meta-analysis of the Effectiveness of Radiofrequency Neurotomy in Managing Chronic Neck Pain. Pain Ther. 2023 Feb;12(1):19-66. doi: 10.1007/s40122-022-00455-0. Epub 2022 Nov 24.Manchikanti L, Knezevic NN, Knezevic E, et al. A Systematic Review and Meta-analysis of the Effectiveness of Radiofrequency Neurotomy in Managing Chronic Neck Pain. Pain Ther. 2023 Feb;12(1):19-66. doi: 10.1007/s40122-022-00455-0. Epub 2022 Nov 24.Trinh K, Graham N, Irnich D, et al. Acupuncture for neck disorders. Cochrane Database Syst Rev. 2016 May 4;(5):CD004870. doi: 10.1002/14651858.CD004870.pub4. Update in: Cochrane Database Syst Rev. 2016 Nov 17;11:CD004870.Trinh K, Graham N, Irnich D, et al. Acupuncture for neck disorders. Cochrane Database Syst Rev. 2016 May 4;(5):CD004870. doi: 10.1002/14651858.CD004870.pub4. Update in: Cochrane Database Syst Rev. 2016 Nov 17;11:CD004870.Vickers AJ, Vertosick EA, Lewith G, et al; Acupuncture Trialists' Collaboration. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. J Pain. 2018 May;19(5):455-74. doi: 10.1016/j.jpain.2017.11.005. Epub 2017 Dec 2.Vickers AJ, Vertosick EA, Lewith G, et al; Acupuncture Trialists' Collaboration. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. J Pain. 2018 May;19(5):455-74. doi: 10.1016/j.jpain.2017.11.005. Epub 2017 Dec 2.Kroeling P, Gross A, Graham N, et al. Electrotherapy for neck pain. Cochrane Database Syst Rev. 2013 Aug 26;(8):CD004251. doi: 10.1002/14651858.CD004251.pub5Kroeling P, Gross A, Graham N, et al. Electrotherapy for neck pain. Cochrane Database Syst Rev. 2013 Aug 26;(8):CD004251. doi: 10.1002/14651858.CD004251.pub5Langevin P, Peloso PM, Lowcock J, et al. Botulinum toxin for subacute/chronic neck pain. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD008626. doi: 10.1002/14651858.CD008626.pub2. Update in: Cochrane Database Syst Rev. 2015;5:CD008626.Langevin P, Peloso PM, Lowcock J, et al. Botulinum toxin for subacute/chronic neck pain. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD008626. doi: 10.1002/14651858.CD008626.pub2. Update in: Cochrane Database Syst Rev. 2015;5:CD008626.Manchikanti L, Kaye AD, Boswell MV, et al. A Systematic Review and Best Evidence Synthesis of the Effectiveness of Therapeutic Facet Joint Interventions in Managing Chronic Spinal Pain. Pain Physician. 2015 JulAug;18(4):E535-82.Manchikanti L, Kaye AD, Boswell MV, et al. A Systematic Review and Best Evidence Synthesis of the Effectiveness of Therapeutic Facet Joint Interventions in Managing Chronic Spinal Pain. Pain Physician. 2015 JulAug;18(4):E535-82.Skljarevski V, Zhang S, Desaiah D, et al. Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixeddose, randomized, double-blind trial. J Pain. 2010;11(12):1282-90. doi: 10.1016/j.jpain.2010.03.002Skljarevski V, Zhang S, Desaiah D, et al. Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixeddose, randomized, double-blind trial. J Pain. 2010;11(12):1282-90. doi: 10.1016/j.jpain.2010.03.002Hernandez-Lucas P, Leiros-Rodriguez R, Lopez-Barreiro J, Garcia-Soidan JL. Is the combination of exercise therapy and health education more effective than usual medical care in the prevention of non-specific back pain? A systematic review with meta-analysis. Ann Med. 2022 Dec;54(1):3107-16. doi: 10.1080/07853890.2022.2140453Hernandez-Lucas P, Leiros-Rodriguez R, Lopez-Barreiro J, Garcia-Soidan JL. Is the combination of exercise therapy and health education more effective than usual medical care in the prevention of non-specific back pain? A systematic review with meta-analysis. Ann Med. 2022 Dec;54(1):3107-16. doi: 10.1080/07853890.2022.2140453Suman A, Dikkers MF, Schaafsma FG, et al. Effectiveness of multifaceted implementation strategies for the implementation of back and neck pain guidelines in health care: a systematic review. Implement Sci. 2016 Sep 20;11(1):126. doi: 10.1186/s13012-016-0482-7Suman A, Dikkers MF, Schaafsma FG, et al. Effectiveness of multifaceted implementation strategies for the implementation of back and neck pain guidelines in health care: a systematic review. Implement Sci. 2016 Sep 20;11(1):126. doi: 10.1186/s13012-016-0482-7

The authors declare that there are no conflicts of interest present.