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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2023-3-85-94</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2035</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Non-specific low back pain: principles and algorithms for successful management of patients in real clinical practice</article-title><trans-title-group xml:lang="ru"><trans-title>Неспецифическая боль в нижней части спины: принципы и алгоритмы успешного ведения пациентов в реальной клинической практике</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2752-4109</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вероника Александровна Головачева - Кафедра нервных болезней и нейрохирургии Института клинической медицины им. Н.В. Склифосовского.</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Veronika Aleksandrovna Golovacheva - Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine.</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><email xlink:type="simple">xoxo.veronicka@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3833-532X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Табеева</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Tabeeva</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии Института клинической медицины им. Н.В. Склифосовского.</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine.</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2845-7323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии Института клинической медицины им. Н.В. Склифосовского.</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine.</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>04</day><month>07</month><year>2023</year></pub-date><volume>15</volume><issue>3</issue><fpage>85</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Golovacheva V.A., Tabeeva G.R., Golovacheva A.A., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Головачева В.А., Табеева Г.Р., Головачева А.А.</copyright-holder><copyright-holder xml:lang="en">Golovacheva V.A., Tabeeva G.R., Golovacheva A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2035">https://nnp.ima-press.net/nnp/article/view/2035</self-uri><abstract><p>Non-specific low back pain (LBP) occurs in most people at least once in a lifetime. In city polyclinics, every fourth patient complains of LBP. During the COVID-19 pandemic, the prevalence of acute non-specific LBP and chronic LBP have increased due to physical inactivity, chronic stress, and anxiety. Musculoskeletal LBP is the second most common cause of disability. In this regard, it is important to consider modern principles for the diagnosis and treatment of non-specific LBP. Diagnostic algorithms, “red flags” (dangerous symptoms), “yellow flags” (chronification factors) in LBP are discussed. Own clinical cases of patients with LBP with “red flags” are presented. Effective drug and non-drug methods of treatment of LBP are considered: patient education, kinesiotherapy, cognitive-behavioral therapy, manual therapy, the use of non-steroidal anti-inflammatory drugs, muscle relaxants. The role of aceclofenac and tolperisone in the treatment of LBP is discussed, clinical studies data on the efficacy and safety of these drugs in pain syndromes are presented. We present our own clinical observation of the successful management of a patient with chronic non-specific LBP.</p></abstract><trans-abstract xml:lang="ru"><p>Неспецифическая боль в нижней части спины (БНЧС) отмечается у большинства людей хотя бы раз в жизни. В городских поликлиниках каждый четвертый пациент предъявляет жалобы на БНЧС. За период пандемии COVID-19 распространенность острой неспецифической БНЧС и хронизация БНЧС увеличились из-за гиподинамии, хронического стресса, тревоги. Скелетно-мышечная БНЧС – вторая по частоте причина снижения трудоспособности. В связи с этим актуально рассмотрение современных принципов диагностики и лечения неспецифической БНЧС. Обсуждаются алгоритмы диагностики, «красные флаги» (симптомы опасности), «желтые флаги» (факторы хронизации) при БНЧС. Приводятся собственные клинические наблюдения пациентов с БНЧС и «красными флагами». Рассматриваются эффективные лекарственные и нелекарственные методы лечения БНЧС: информирование пациента, кинезиотерапия, когнитивно-поведенческая терапия, мануальная терапия, использование нестероидных противовоспалительных средств, миорелаксантов. Обсуждается роль ацеклофенака и толперизона в лечении БНЧС, приводятся данные клинических исследований эффективности и безопасности этих препаратов при болевых синдромах. Продемонстрировано собственное клиническое наблюдение по успешному ведению пациентки с хронической неспецифической БНЧС.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль в нижней части спины</kwd><kwd>скелетно-мышечная боль</kwd><kwd>диагностика</kwd><kwd>«красные флаги»</kwd><kwd>«желтые флаги»</kwd><kwd>лечение</kwd><kwd>нестероидные противовоспалительные средства</kwd><kwd>миорелаксанты</kwd><kwd>ацеклофенак</kwd><kwd>толперизон</kwd><kwd>кинезиотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lower back pain</kwd><kwd>musculoskeletal pain</kwd><kwd>diagnostics</kwd><kwd>“red flags”</kwd><kwd>“yellow flags”</kwd><kwd>treatment</kwd><kwd>non-steroidal anti-inflammatory drugs</kwd><kwd>muscle relaxants</kwd><kwd>aceclofenac</kwd><kwd>tolperisone</kwd><kwd>kinesiotherapy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья спонсируется компанией «Гедеон Рихтер»</funding-statement><funding-statement xml:lang="en">This article has been supported by Gedeon Richter</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Головачева ВА, Головачева АА, Фатеева ТГ. 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