<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2023-2-98-105</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2001</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Diagnosis and therapy of obsessive-compulsive spectrum disorders in general medical and neurological practice</article-title><trans-title-group xml:lang="ru"><trans-title>Диагностика и терапия расстройств обсессивно-компульсивного спектра в общемедицинской и неврологической практике</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2228-6316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петелин</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petelin</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9543-4041</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гамирова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gamirova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991</p></bio><email xlink:type="simple">aysylu.gamirova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8863-8241</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокина</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokina</surname><given-names>O. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5046-6699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0061-1798</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семин</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Semin</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>111142, Москва, ул. Плеханова, 9, стр. 2</p></bio><bio xml:lang="en"><p>9, Plekhanova St., Build. 2, Moscow 111142</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-8319-9970</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болтуева</surname><given-names>М. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Boltueva</surname><given-names>M. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1667-5355</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волель</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volel</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Большая Пироговская, 2, стр. 4; 115522, Москва, Каширское шоссе, 34</p></bio><bio xml:lang="en"><p>2, Bolshaya Pirogovska St., Build. 4, Moscow 119991; 34, Kashirskoe Shosse, 115522 Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО Клиника «Спасение»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>LLC «Spasenie» Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет);&#13;
ФГБНУ «Научный центр психического здоровья»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia;&#13;
Mental Health Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>04</month><year>2023</year></pub-date><volume>15</volume><issue>2</issue><fpage>98</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Petelin D.S., Gamirova A.N., Sorokina O.Y., Troshina D.V., Semin S.A., Boltueva M.S., Volel B.A., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Петелин Д.С., Гамирова А.Н., Сорокина О.Ю., Трошина Д.В., Семин С.А., Болтуева М.Ш., Волель Б.А.</copyright-holder><copyright-holder xml:lang="en">Petelin D.S., Gamirova A.N., Sorokina O.Y., Troshina D.V., Semin S.A., Boltueva M.S., Volel B.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2001">https://nnp.ima-press.net/nnp/article/view/2001</self-uri><abstract><p>Obsessive-compulsive spectrum disorders are widely represented in the population and often encountered in clinical practice, but they are not well diagnosed and many patients do not receive proper treatment. This review discusses the prevalence of obsessive-compulsive spectrum disorders, their negative impact on the level of functioning of patients, comorbidity with other mental disorders, diagnosis and differential diagnosis. The emphasis is put on changes in approaches to the diagnosis of obsessive-compulsive disorders that will occur after the introduction of the International Classification of Diseases of the 11th revision (ICD-11). Approaches to the treatment of obsessive-compulsive spectrum disorders are discussed in accordance with the principles of evidence-based medicine, and the use of selective serotonin reuptake inhibitors and cognitive behavioral therapy as first-line therapy is justified.</p></abstract><trans-abstract xml:lang="ru"><p>Расстройства обсессивно-компульсивного спектра широко представлены среди населения и часто встречаются в клинической практике, однако они недостаточно хорошо диагностируются и многие пациенты не получают должного лечения. В настоящем обзоре обсуждаются распространенность расстройств обсессивно-компульсивного спектра, их негативное влияние на уровень функционирования пациентов, коморбидность с другими психическими расстройствами, диагностика и дифференциальная диагностика. Акцент сделан на изменениях в подходах к диагностике обсессивно-компульсивных расстройств, которые произойдут после введения в практику Международной классификации болезней 11-го пересмотра (МКБ-11). Обсуждаются подходы к терапии расстройств обсессивно-компульсивного спектра в соответствии с принципами доказательной медицины, обосновано применение селективных ингибиторов обратного захвата серотонина и когнитивно-поведенческой терапии в качестве терапии первой линии.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обсессивно-компульсивное расстройство</kwd><kwd>ипохондрия</kwd><kwd>дисморфическое расстройство</kwd><kwd>патологическое накопительство</kwd><kwd>селективные ингибиторы обратного захвата серотонина</kwd><kwd>когнитивно-поведенческая терапия</kwd><kwd>флувоксамин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obsessive-compulsive disorder</kwd><kwd>hypochondria</kwd><kwd>dysmorphic disorder</kwd><kwd>pathological hoarding</kwd><kwd>selective serotonin reuptake inhibitors</kwd><kwd>cognitive behavioral therapy</kwd><kwd>fluvoxamine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition Text Revision: DSM-5-TR. Washington, DC: American Psychiatric Association Publishing; 2022.</mixed-citation><mixed-citation xml:lang="en">Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition Text Revision: DSM-5-TR. Washington, DC: American Psychiatric Association Publishing; 2022.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mental Health: Facing the Challenges, Building Solutions: Report from the WHO European Ministerial Conference. Copenhagen: WHO Regional Office for Europe; 2005. 181 p.</mixed-citation><mixed-citation xml:lang="en">Mental Health: Facing the Challenges, Building Solutions: Report from the WHO European Ministerial Conference. Copenhagen: WHO Regional Office for Europe; 2005. 181 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Velloso P, Piccinato C, Ferrao Y, et al. Clinical predictors of quality of life in a large sample of adult obsessive-compulsive disorder outpatients. Compr Psychiatry. 2018;86:82-90. doi: 10.1016/j.comppsych.2018.07.007</mixed-citation><mixed-citation xml:lang="en">Velloso P, Piccinato C, Ferrao Y, et al. Clinical predictors of quality of life in a large sample of adult obsessive-compulsive disorder outpatients. Compr Psychiatry. 2018;86:82-90. doi: 10.1016/j.comppsych.2018.07.007</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Stein DJ, Costa DLC, Lochner C, et al. Obsessive-compulsive disorder. Nat Rev Dis Primers. 2019 Aug 1;5(1):52. doi: 10.1038/s41572-019-0102-3</mixed-citation><mixed-citation xml:lang="en">Stein DJ, Costa DLC, Lochner C, et al. Obsessive-compulsive disorder. Nat Rev Dis Primers. 2019 Aug 1;5(1):52. doi: 10.1038/s41572-019-0102-3</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ruscio AM, Stein DJ, Chiu WT, Kessler RC. The epidemiology of obsessivecompulsive disorder in the National Comorbidity Survey Replication. Mol Psychiatry. 2010;15(1):53-63. doi: 10.1038/mp.2008.94</mixed-citation><mixed-citation xml:lang="en">Ruscio AM, Stein DJ, Chiu WT, Kessler RC. The epidemiology of obsessivecompulsive disorder in the National Comorbidity Survey Replication. Mol Psychiatry. 2010;15(1):53-63. doi: 10.1038/mp.2008.94</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mayerovitch JI, du Fort GG, Kakuma R, et al. Treatment seeking for obsessive-compulsive disorder: role of obsessive-compulsive disorder symptoms and comorbid psychiatric diagnoses. Compr Psychiatry. 2003;44(2):162-8. doi: 10.1053/comp.2003.50005</mixed-citation><mixed-citation xml:lang="en">Mayerovitch JI, du Fort GG, Kakuma R, et al. Treatment seeking for obsessive-compulsive disorder: role of obsessive-compulsive disorder symptoms and comorbid psychiatric diagnoses. Compr Psychiatry. 2003;44(2):162-8. doi: 10.1053/comp.2003.50005</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Torres AR, Prince MJ, Bebbington PE, et al. Treatment seeking by individuals with obsessivecompulsive disorder from the british psychiatric morbidity survey of 2000. Psychiatr Serv. 2007;58(7):977-82. doi: 10.1176/ps.2007.58.7.977</mixed-citation><mixed-citation xml:lang="en">Torres AR, Prince MJ, Bebbington PE, et al. Treatment seeking by individuals with obsessivecompulsive disorder from the british psychiatric morbidity survey of 2000. Psychiatr Serv. 2007;58(7):977-82. doi: 10.1176/ps.2007.58.7.977</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Costa DLDC, de Campos AP, Pereira CAB, et al. Latency to treatment seeking in patients with obsessive-compulsive disorder: Results from a large multicenter clinical sample. Psychiatry Res. 2022;312:114567. doi: 10.1016/j.psychres.2022.114567</mixed-citation><mixed-citation xml:lang="en">Costa DLDC, de Campos AP, Pereira CAB, et al. Latency to treatment seeking in patients with obsessive-compulsive disorder: Results from a large multicenter clinical sample. Psychiatry Res. 2022;312:114567. doi: 10.1016/j.psychres.2022.114567</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ziegler S, Bednasch K, Baldofski S, Rummel-Kluge C. Long durations from symptom onset to diagnosis and from diagnosis to treatment in obsessive-compulsive disorder: A retrospective self-report study. PLoS One. 2021 Dec 13;16(12):e0261169. doi: 10.1371/journal.pone.0261169</mixed-citation><mixed-citation xml:lang="en">Ziegler S, Bednasch K, Baldofski S, Rummel-Kluge C. Long durations from symptom onset to diagnosis and from diagnosis to treatment in obsessive-compulsive disorder: A retrospective self-report study. PLoS One. 2021 Dec 13;16(12):e0261169. doi: 10.1371/journal.pone.0261169</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nestadt G, Samuels JF, Romanoski AJ, et al. Obsessions and compulsions in the community. Acta Psychiatr Scand. 1994;89(4):219-24. doi: 10.1111/j.1600-0447.1994.tb01504.x</mixed-citation><mixed-citation xml:lang="en">Nestadt G, Samuels JF, Romanoski AJ, et al. Obsessions and compulsions in the community. Acta Psychiatr Scand. 1994;89(4):219-24. doi: 10.1111/j.1600-0447.1994.tb01504.x</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Fireman B, Koran LM, Leventhal JL, Jacobson A. The prevalence of clinically recognized obsessive-compulsive disorder in a large health maintenance organization. Am J Psychiatry. 2001;158(11):1904-10. doi: 10.1176/appi.ajp.158.11.1904</mixed-citation><mixed-citation xml:lang="en">Fireman B, Koran LM, Leventhal JL, Jacobson A. The prevalence of clinically recognized obsessive-compulsive disorder in a large health maintenance organization. Am J Psychiatry. 2001;158(11):1904-10. doi: 10.1176/appi.ajp.158.11.1904</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Karno M, Golding JM, Sorenson SB, Burnam MA. The epidemiology of obsessivecompulsive disorder in five US communities. Arch Gen Psychiatry. 1988;45(12):1094-9. doi: 10.1001/archpsyc.1988.01800360042006</mixed-citation><mixed-citation xml:lang="en">Karno M, Golding JM, Sorenson SB, Burnam MA. The epidemiology of obsessivecompulsive disorder in five US communities. Arch Gen Psychiatry. 1988;45(12):1094-9. doi: 10.1001/archpsyc.1988.01800360042006</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kendrick T, Peveler R. Guidelines for the management of depression: NICE work? Br J Psychiatry. 2010;197(5):345-7. doi: 10.1192/bjp.bp.109.074575</mixed-citation><mixed-citation xml:lang="en">Kendrick T, Peveler R. Guidelines for the management of depression: NICE work? Br J Psychiatry. 2010;197(5):345-7. doi: 10.1192/bjp.bp.109.074575</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Ахапкин РВ, Маслова МА. Когнитивные нарушения при непсихотических депрессивных расстройствах. Российский психиатрический журнал. 2015;(1):43-50.</mixed-citation><mixed-citation xml:lang="en">Akhapkin RV, Maslova MA. Cognitive impairments in non-psychotic depressive disorders. Rossiyskiy psikhiatricheskiy zhurnal = Russian Journal of Psychiatry. 2015;(1):43-50 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Veldhuis J, Dieleman JP, Wohlfarth T, et al. Incidence and prevalence of “diagnosed OCD” in a primary care, treatment seeking, population. Int J Psychiatry Clin Pract. 2012;16(2):85-92. doi: 10.3109/13651501.2011.617454</mixed-citation><mixed-citation xml:lang="en">Veldhuis J, Dieleman JP, Wohlfarth T, et al. Incidence and prevalence of “diagnosed OCD” in a primary care, treatment seeking, population. Int J Psychiatry Clin Pract. 2012;16(2):85-92. doi: 10.3109/13651501.2011.617454</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Волель БА, Петелин ДС, Ахапкин РВ, Малютина АА. Когнитивные нарушения при тревожных расстройствах. Неврология, нейропсихиатрия, психосоматика. 2018;10(1):78-82. doi: 10.14412/2074-2711-2018-1-78-82</mixed-citation><mixed-citation xml:lang="en">Volel BA, Petelin DS, Akhapkin RV, Malyutina AA. Cognitive impairment in anxiety disorders. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2018;10(1):78-82. doi: 10.14412/2074-2711-2018-1-78-82 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Rees CS, Anderson RA, Kane RT, Finlay-Jones AL. Online Obsessive-Compulsive Disorder Treatment: Preliminary Results of the “OCD? Not Me!” Self-Guided InternetBased Cognitive Behavioral Therapy Program for Young People. JMIR Ment Health. 2016 Jul 5;3(3):e29. doi: 10.2196/mental.5363</mixed-citation><mixed-citation xml:lang="en">Rees CS, Anderson RA, Kane RT, Finlay-Jones AL. Online Obsessive-Compulsive Disorder Treatment: Preliminary Results of the “OCD? Not Me!” Self-Guided InternetBased Cognitive Behavioral Therapy Program for Young People. JMIR Ment Health. 2016 Jul 5;3(3):e29. doi: 10.2196/mental.5363</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Волель БА. Современные психофармакологические подходы в лечении обсессивно-компульсивных расстройств. Психиатрия и психофармакотерапия. 2002;(3):104-6.</mixed-citation><mixed-citation xml:lang="en">Volel BA. Modern psychotherapeutic methods of treatment of obsessive-compulsive disorder. Psikhiatriya i psikhofarmakoterapiya = Psychiatry and Psychotherapy. 2002;(3):104-6 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Белова НА, Колюцкая ЕВ. Феномен «моральной мизофобии» в клинике шизофрении. Журнал неврологии и психиатрии им. С.С. Корсакова. 2012;112(6):13-7.</mixed-citation><mixed-citation xml:lang="en">Belova NA, Kolyutskaya EV. Moral mysophobia phenomenon in schizophrenia. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2012;112(6):13-7 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sharma LP, Reddy YCJ. Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder. Indian J Psychiatry. 2019 Jan;61(Suppl 1):S140-S148. doi: 10.4103/psychiatry.IndianJPsychiatry_527_18</mixed-citation><mixed-citation xml:lang="en">Sharma LP, Reddy YCJ. Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder. Indian J Psychiatry. 2019 Jan;61(Suppl 1):S140-S148. doi: 10.4103/psychiatry.IndianJPsychiatry_527_18</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Sevilla-Cermeno L, Andren P, Hillborg M, et al. Insomnia in pediatric obsessive-compulsive disorder: prevalence and association with multimodal treatment outcomes in a naturalistic clinical setting. Sleep Med. 2019 Apr;56:104-10. doi: 10.1016/j.sleep.2018.12.024. Epub 2019 Jan 30.</mixed-citation><mixed-citation xml:lang="en">Sevilla-Cermeno L, Andren P, Hillborg M, et al. Insomnia in pediatric obsessive-compulsive disorder: prevalence and association with multimodal treatment outcomes in a naturalistic clinical setting. Sleep Med. 2019 Apr;56:104-10. doi: 10.1016/j.sleep.2018.12.024. Epub 2019 Jan 30.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Pinciotti CM, Riemann BC, Abramowitz JS. Intolerance of uncertainty and obsessive-compulsive disorder dimensions. J Anxiety Disord. 2021;81:102417. doi: 10.1016/j.janxdis.2021.102417</mixed-citation><mixed-citation xml:lang="en">Pinciotti CM, Riemann BC, Abramowitz JS. Intolerance of uncertainty and obsessive-compulsive disorder dimensions. J Anxiety Disord. 2021;81:102417. doi: 10.1016/j.janxdis.2021.102417</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Beucke JC, Sepulcre J, Talukdar T, et al. Abnormally high degree connectivity of the orbitofrontal cortex in obsessive-compulsive disorder. JAMA Psychiatry. 2013;70(6):619-29. doi: 10.1001/jamapsychiatry.2013.173</mixed-citation><mixed-citation xml:lang="en">Beucke JC, Sepulcre J, Talukdar T, et al. Abnormally high degree connectivity of the orbitofrontal cortex in obsessive-compulsive disorder. JAMA Psychiatry. 2013;70(6):619-29. doi: 10.1001/jamapsychiatry.2013.173</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Bandelow B, Allgulander C, Baldwin DS, et al. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders. World J Biol Psychiatry. 2023;24(2):79-117. doi: 10.1080/15622975.2022.2086295</mixed-citation><mixed-citation xml:lang="en">Bandelow B, Allgulander C, Baldwin DS, et al. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders. World J Biol Psychiatry. 2023;24(2):79-117. doi: 10.1080/15622975.2022.2086295</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Dingemans AE, Volkmer SA, Mulkens S, et al. The obsessive-compulsive spectrum: A network analysis. Psychiatry Res. 2022;308:114351. doi: 10.1016/j.psychres.2021.114351</mixed-citation><mixed-citation xml:lang="en">Dingemans AE, Volkmer SA, Mulkens S, et al. The obsessive-compulsive spectrum: A network analysis. Psychiatry Res. 2022;308:114351. doi: 10.1016/j.psychres.2021.114351</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ravindran AV, da Silva TL, Ravindran LN, et al. Obsessive-compulsive spectrum disorders: a review of the evidence-based treatments. Can J Psychiatry. 2009;54(5):331-43. doi: 10.1177/070674370905400507</mixed-citation><mixed-citation xml:lang="en">Ravindran AV, da Silva TL, Ravindran LN, et al. Obsessive-compulsive spectrum disorders: a review of the evidence-based treatments. Can J Psychiatry. 2009;54(5):331-43. doi: 10.1177/070674370905400507</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Стась СЮ. Обсессии контрастного содержания (аспекты коморбидности с расстройствами бредового регистра). Психиатрия (научно-практический журнал). 2007;(2):7-15.</mixed-citation><mixed-citation xml:lang="en">Stas’ SYu. Contrast content obsessions and aspects of comorbidity with delusional disorders. Psikhiatriya (nauchno-prakticheskiy zhurnal) = Psychiatry (Research and Practice Journal). 2007;(2):7-15 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Загороднова ЮБ, Колюцкая ЕВ. К проблеме обсессивного бреда. Психиатрия. 2009;(1-37):7-11.</mixed-citation><mixed-citation xml:lang="en">Zagorodnova YuB, Kolyutskaya EV. Obsessive delusion problem. Psikhiatriya = Psychiatry. 2009;(1-37):7-11 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Guillen-Font MA, Cervera M, Puigoriol E, et al. Insight in Obsessive-Compulsive Disorder: Relationship With Sociodemographic and Clinical Characteristics. J Psychiatr Pract. 2021 Nov 5;27(6):427-38. doi: 10.1097/PRA.0000000000000580</mixed-citation><mixed-citation xml:lang="en">Guillen-Font MA, Cervera M, Puigoriol E, et al. Insight in Obsessive-Compulsive Disorder: Relationship With Sociodemographic and Clinical Characteristics. J Psychiatr Pract. 2021 Nov 5;27(6):427-38. doi: 10.1097/PRA.0000000000000580</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Gaebel W, Stricker J, Kerst A. Changes from ICD-10 to ICD-11 and future directions in psychiatric classification. Dialogues Clin Neurosci. 2020 Mar;22(1):7-15. doi: 10.31887/DCNS.2020.22.1/wgaebel</mixed-citation><mixed-citation xml:lang="en">Gaebel W, Stricker J, Kerst A. Changes from ICD-10 to ICD-11 and future directions in psychiatric classification. Dialogues Clin Neurosci. 2020 Mar;22(1):7-15. doi: 10.31887/DCNS.2020.22.1/wgaebel</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Fenske JN, Petersen K. ObsessiveCompulsive Disorder: Diagnosis and Management. Am Fam Physician. 2015 Nov 15;92(10):896-903.</mixed-citation><mixed-citation xml:lang="en">Fenske JN, Petersen K. ObsessiveCompulsive Disorder: Diagnosis and Management. Am Fam Physician. 2015 Nov 15;92(10):896-903.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Conelea CA, Walther MR, Freeman JB, et al. Tic-related obsessive-compulsive disorder (OCD): phenomenology and treatment outcome in the Pediatric OCD Treatment Study II. J Am Acad Child Adolesc Psychiatry. 2014;53(12):1308-16. doi: 10.1016/j.jaac.2014.09.014</mixed-citation><mixed-citation xml:lang="en">Conelea CA, Walther MR, Freeman JB, et al. Tic-related obsessive-compulsive disorder (OCD): phenomenology and treatment outcome in the Pediatric OCD Treatment Study II. J Am Acad Child Adolesc Psychiatry. 2014;53(12):1308-16. doi: 10.1016/j.jaac.2014.09.014</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">The National Institute for Health and Care Excellence (NICE). Obsessive-compulsive disorder and body dysmorphic disorder: treatment clinical guideline, 2005. Available from: https://www.nice.org.uk/guidance/CG31/chapter/1-Guidance#steps-35-treatment-optionsfor-people-with-ocd-or-bdd</mixed-citation><mixed-citation xml:lang="en">The National Institute for Health and Care Excellence (NICE). Obsessive-compulsive disorder and body dysmorphic disorder: treatment clinical guideline, 2005. Available from: https://www.nice.org.uk/guidance/CG31/chapter/1-Guidance#steps-35-treatment-optionsfor-people-with-ocd-or-bdd</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">American Psychiatric Association (APA) Practice Guideline for Obsessive-Compulsive Disorder, 2007. Available from: https://psychiatryonline.org/guidelines</mixed-citation><mixed-citation xml:lang="en">American Psychiatric Association (APA) Practice Guideline for Obsessive-Compulsive Disorder, 2007. Available from: https://psychiatryonline.org/guidelines</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Bloch MH, McGuire J, Landeros-Weisenberger A, et al. Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder. Mol Psychiatry. 2010 Aug;15(8):850-5. doi: 10.1038/mp.2009.50. Epub 2009 May 26.</mixed-citation><mixed-citation xml:lang="en">Bloch MH, McGuire J, Landeros-Weisenberger A, et al. Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder. Mol Psychiatry. 2010 Aug;15(8):850-5. doi: 10.1038/mp.2009.50. Epub 2009 May 26.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Edinoff AN, Akuly HA, Hanna TA, et al. Selective Serotonin Reuptake Inhibitors and Adverse Effects: A Narrative Review. Neurol Int. 2020 Sep 8;81(5):19ac13182. doi: 10.4088/JCP.19ac13182</mixed-citation><mixed-citation xml:lang="en">Edinoff AN, Akuly HA, Hanna TA, et al. Selective Serotonin Reuptake Inhibitors and Adverse Effects: A Narrative Review. Neurol Int. 2020 Sep 8;81(5):19ac13182. doi: 10.4088/JCP.19ac13182</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Kayser RR. Pharmacotherapy for Treatment-Resistant Obsessive-Compulsive Disorder. J Clin Psychiatry. 2020 Sep 8;81(5):19ac13182. doi: 10.4088/JCP.19ac13182</mixed-citation><mixed-citation xml:lang="en">Kayser RR. Pharmacotherapy for Treatment-Resistant Obsessive-Compulsive Disorder. J Clin Psychiatry. 2020 Sep 8;81(5):19ac13182. doi: 10.4088/JCP.19ac13182</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Рагимова АА, Петелин ДС, Кожокару АВ и др. Применение транскраниальной магнитной стимуляции в психиатрической и психоневрологической практике: учебное пособие. Москва: Центральная государственная медицинская академия Управления делами Президента Российской Федерации; 2019. doi: 10.12731/jouhvf</mixed-citation><mixed-citation xml:lang="en">Ragimova AA, Petelin DS, Kojokaru AV, et al. Primeneniye transkranial'noy magnitnoy stimulyatsii v psikhiatricheskoy i psikhonevrologicheskoy praktike: uchebnoye posobiye [Use of transcranial magnetic stimulation in psychiatry and psychoneurological practice: a textbook. Moscow: Central State Medical Academy of the Administration of the President of the Russian Federation; 2019. doi: 10.12731/jouhvf (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Eddy KT, Dutra L, Bradley R, Westen D. A multidimensional meta-analysis of psychotherapy and pharmacotherapy for obsessive-compulsive disorder. Clin Psychol Rev. 2004;24(8):1011-30. doi: 10.1016/j.cpr.2004.08.004</mixed-citation><mixed-citation xml:lang="en">Eddy KT, Dutra L, Bradley R, Westen D. A multidimensional meta-analysis of psychotherapy and pharmacotherapy for obsessive-compulsive disorder. Clin Psychol Rev. 2004;24(8):1011-30. doi: 10.1016/j.cpr.2004.08.004</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
