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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2022-4-44-50</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1860</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>A clinical case of mechanical recanalization of recurrent cerebral embolism in the hyperacute period of ischemic stroke with hemorrhagic transformation</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай механической реканализации повторной церебральной эмболии в острейшем периоде ишемического инсульта, протекавшего с геморрагической трансформацией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8162-2359</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муртазалиева</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Murtazalieva</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джавгарат Магомедовна Муртазалиева127644, Москва, ул. Лобненская, 10</p></bio><bio xml:lang="en"><p>Dzhavgarat Magomedovna Murtazalieva127644, Moscow, Lobnenskaya St., 10</p></bio><email xlink:type="simple">djana.murt@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5563-4890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Закарьяева</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakaryaeva</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>127644, Москва, ул. Лобненская, 10</p></bio><bio xml:lang="en"><p>127644, Moscow, Lobnenskaya St., 10</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4608-302X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Струценко</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Strutsenko</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>127644, Москва, ул. Лобненская, 10</p></bio><bio xml:lang="en"><p>127644, Moscow, Lobnenskaya St., 10</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2659-1211</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипов</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipov</surname><given-names>I. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>127644, Москва, ул. Лобненская, 10</p></bio><bio xml:lang="en"><p>127644, Moscow, Lobnenskaya St., 10</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8277-2255</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шогенов</surname><given-names>З. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shogenov</surname><given-names>Z. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>127644, Москва, ул. Лобненская, 10</p></bio><bio xml:lang="en"><p>127644, Moscow, Lobnenskaya St., 10</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Городская клиническая больница им. В.В. Вересаева Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital named after V.V. Veresaev, Department of Health of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>23</day><month>08</month><year>2022</year></pub-date><volume>14</volume><issue>4</issue><fpage>44</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Murtazalieva D.M., Zakaryaeva A.R., Strutsenko M.V., Osipov I.Y., Shogenov Z.S., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Муртазалиева Д.М., Закарьяева А.Р., Струценко М.В., Осипов И.Ю., Шогенов З.С.</copyright-holder><copyright-holder xml:lang="en">Murtazalieva D.M., Zakaryaeva A.R., Strutsenko M.V., Osipov I.Y., Shogenov Z.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1860">https://nnp.ima-press.net/nnp/article/view/1860</self-uri><abstract><p>Currently, there is no single algorithm for the treatment of acute tandem occlusion of the internal carotid artery (ICA) and middle cerebral artery (MCA). The article presents the clinical case of ischemic stroke, which developed 10 days after the first ischemic episode with hemorrhagic transformation. As reperfusion therapy, thrombectomy from the M1 segment of the left MCA and simultaneous stenting of the left ICA were performed. The use of dual antiplatelet therapy at a loading dose in this clinical case was justified by the risk of stent thrombosis, but this increased the risk of recurrent hemorrhagic transformation. Follow-up of the patient for 90 days after this vascular event showed a favorable clinical outcome without hemorrhagic complications. The presented clinical case is extremely rare and shows one of the possible approaches in the management of patients with tandem lesions of the brachiocephalic arteries with a history of intracranial hemorrhagic complications. To develop a unified algorithm for managing acute tandem occlusion in recurrent ischemic strokes, more observations are needed.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время не существует единого алгоритма лечения острой тандемной окклюзии внутренней сонной артерии (ВСА) и средней мозговой артерии (СМА). В статье представлено наблюдение пациентки с ишемическим инсультом, который развился спустя 10 дней после первого ишемического эпизода, проходившего с геморрагической трансформацией. В качестве реперфузионной терапии проведены тромбэктомия из сегмента М1 левой СМА и одномоментное стентирование левой ВСА. Применение двойной антиагрегантной терапии в нагрузочной дозе в данном клиническом случае было обосновано риском тромбоза стента, однако это повышало риск повторной геморрагической трансформации. Наблюдение за пациенткой в течение 90 дней после данного сосудистого события показало благоприятный клинический исход без геморрагических осложнений. Приведенный клинический случай относится к крайне редким и показывает один из возможных подходов в ведении пациентов с тандемным поражением брахиоцефальных артерий при внутричерепных геморрагических осложнениях в анамнезе. Для разработки единого алгоритма ведения острой тандемной окклюзии при повторных ишемических инсультах необходимо большее количество наблюдений.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемический инсульт</kwd><kwd>механическая тромбэктомия</kwd><kwd>перфузионная компьютерная томография</kwd><kwd>репефузионная терапия</kwd><kwd>тандемная окклюзия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic stroke</kwd><kwd>mechanical thrombectomy</kwd><kwd>perfusion computed tomography</kwd><kwd>reperfusion therapy</kwd><kwd>tandem occlusion</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Adams HP, Brott TG, Furlan AJ, et al. 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