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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2022-3-62-67</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1825</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Hemimasticatory spasm: possibilities of treatment with injections of botulinum neuroprotein type A (case report)</article-title><trans-title-group xml:lang="ru"><trans-title>Гемимастикаторный спазм: возможности лечения инъекциями ботулинического нейропротеина типа А (клинический случай)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3990-3843</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валиева</surname><given-names>Л. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Valieva</surname><given-names>L. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра челюстно-лицевой хирургии им. акад. Н. Н. Бажанова Института стоматологии им. Е. В. Боровского</p><p>119048, Москва, ул. Доватора, 15, стр. 1</p></bio><bio xml:lang="en"><p>Department of Maxillofacial Surgery named after N. N. Bazhanov, Institute of Dentistry named after E. V. Borovsky</p><p>8, Trubetskay St., Moscow 119991</p><p> </p></bio><email xlink:type="simple">leyka3@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9620-3547</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панкратов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pankratov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра челюстно-лицевой хирургии им. акад. Н. Н. Бажанова Института стоматологии им. Е. В. Боровского; кафедра общей и хирургической стоматологии</p><p>119048, Москва, ул. Доватора, 15, стр. 1;</p><p>129090, Москва, 2-й Троицкий пер., 6а, стр. 13</p></bio><bio xml:lang="en"><p>Department of Maxillofacial Surgery named after N. N. Bazhanov, Institute of Dentistry named after E.V. Borovsky; Department of General and Surgical Dentistry, Medical Academy of Continuous Professional Education, Ministry of Health of Russia</p><p>8, Trubetskay St., Moscow 119991;</p><p>2/1, Barrikadnaya St., Build. 1, Moscow 125993</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2225-3642</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>О. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>O. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра нервных болезней Института постдипломного образования</p><p>111123, Москва, шоссе Энтузиастов, 86</p></bio><bio xml:lang="en"><p>Department of Nervous Disease, Institute of Postgraduate Education</p><p>8, Trubetskay St., Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России (Сеченовский Университет); ФГБУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University);</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2022</year></pub-date><volume>14</volume><issue>3</issue><fpage>62</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Valieva L.U., Pankratov A.S., Orlova O.R., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Валиева Л.У., Панкратов А.С., Орлова О.Р.</copyright-holder><copyright-holder xml:lang="en">Valieva L.U., Pankratov A.S., Orlova O.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1825">https://nnp.ima-press.net/nnp/article/view/1825</self-uri><abstract><p>Objective: to study the possibilities and effectiveness of treatment of patients with hemimasticatory spasm (HMS) with injections of botulinum neuroprotein type A (BNPA). The authors present a clinical case of long-term HMS: a 50-year-old patient, who suffered from the age of 20 from frequent involuntary muscle contractions that occurred in the temporal and masticatory muscles of the left half of the face. The patient was observed by neurologists for a long time, while the prescribed therapy did not have a satisfactory result. In the process of a comprehensive examination of the patient, in addition to intense involuntary contraction and pronounced hypertrophy of the affected muscles, secondary compensatory changes in other masticatory muscles were revealed, both on the side of the lesion and on the opposite side. BNPA treatment led to a robust improvement in the patient's condition.</p><p>For patients with a long course of HMS and hypertrophy of the muscles involved in the pathological process, the use of bilateral injections of BNPA is the method of choice, since it not only effectively reduces the number of episodes, but also restores muscle balance, and also restores the motor function of the entire masticatory muscle group.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования – изучить возможности и эффективность лечения пациентов с гемимастикаторным спазмом (ГМС) инъекциями ботулинического нейропротеина типа А (БНПА). Авторами представлен клинический случай ГМС длительного течения: пациент 50 лет, который с двадцатилетнего возраста страдал частыми непроизвольными мышечными сокращениями, возникающими в височной и собственно жевательной мышцах левой половины лица, длительное время наблюдался у неврологов, при этом назначаемая терапия не приносила удовлетворительного результата. В процессе комплексного обследования пациента, кроме интенсивного непроизвольного сокращения и выраженной гипертрофии пораженных мышц, выявлены вторичные компенсаторные изменения в других жевательных мышцах, как на стороне поражения, так и на противоположной. Лечение БНПА привело к заметному улучшению состояния пациента.</p><p>Для пациентов с длительным течением ГМС и гипертрофией вовлеченных в патологический процесс мышц применение двусторонних инъекций БНПА является методом выбора, поскольку оно не только эффективно снижает число эпизодов, но и возвращает мышечный баланс, а также восстанавливает двигательную функцию всей группы жевательных мышц.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гемимастикаторный спазм</kwd><kwd>ботулинический нейропротеин</kwd><kwd>ботулинотерапия</kwd><kwd>непроизвольное сокращение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hemimasticatory spasm</kwd><kwd>botulinum neuroprotein</kwd><kwd>botulinum therapy</kwd><kwd>involuntary contraction</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья спонсируется компанией «Иннофарм».</funding-statement><funding-statement xml:lang="en">This article has been supported by Innopharm.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Christie C, Rodriguez-Quiroga SA, Arakaki T, et al. 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