nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2022-1-69-75nnp-1752Research ArticleREVIEWSОБЗОРЫHormone therapy for menstrual-associated migraine: pros and consГормональная терапия менструально-ассоциированной мигрени: за и противhttps://orcid.org/0000-0002-9924-6689КирьяноваЕ. А.KiryanovaE. A.

кафедра нервных болезней и нейрохирургии Института клинической медицины,

119021, Москва, ул. Россолимо, 11, стр. 1

Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine, 

11, Rossolimo St., Build. 1, Moscow 119021

terraaeternita@mail.ruhttps://orcid.org/0000-0002-3833-532XТабееваГ. Р.ТabeevaG. R.

кафедра нервных болезней и нейрохирургии Института клинической медицины,

119021, Москва, ул. Россолимо, 11, стр. 1

Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine, 

11, Rossolimo St., Build. 1, Moscow 119021

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation2022260220221416975Copyright © Kiryanova E.A., Тabeeva G.R., 20222022Кирьянова Е.А., Табеева Г.Р.Kiryanova E.A., Тabeeva G.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1752

About 60% of women report menstrual-associated migraine attacks, characterized by a higher intensity and duration and more pronounced treatment resistance. Often, preventive treatment with drugs aimed to relieve menstrual attacks – non-steroidal anti-inflammatory drugs and triptans – is difficult in these patients due to a high risk of medication-overuse headache. In addition, due to a hormonal trigger – a perimenstrual decrease in estrogen – the effect of hormonal contraceptives on migraine attacks has been studied for a long time. This article discusses the results of studies indicating the successful administration of specific hormone therapy regimens, especially in patients with concomitant gynecological pathology or in patients using these drugs for contraception. 

Около 60% женщин отмечают менструально-ассоциированные приступы мигрени, которые характеризуются более высокой интенсивностью и длительностью, а также более выраженной резистентностью к лечению. Зачастую у данных пациенток профилактическое лечение с помощью препаратов для купирования менструальных приступов – нестероидных противовоспалительных средств и триптанов – затруднено вследствие высокого риска развития лекарственно-индуцированной головной боли. В связи с наличием гормонального триггера в виде перименструального снижения эстрогена длительное время изучается влияние гормональных контрацептивов на приступы мигрени. В статье обсуждаются результаты исследований, указывающие на успешное применение определенных схем гормональной терапии, особенно у пациенток с сопутствующей гинекологической патологией или у женщин, применяющих данные гормональные препараты в целях контрацепции. 

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The authors declare that there are no conflicts of interest present.