nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2021-6-142-146nnp-1720Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯAtrial septal defects: the role in the development of cerebral circulation disorders caused by paradoxical embolismДефекты межпредсердной перегородки: роль в развитии нарушений мозгового кровообращения по механизму парадоксальной эмболииhttps://orcid.org/0000-0003-3124-2443БелопасоваА. В.BelopasovaA. V.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

belopasova@neurology.ruhttps://orcid.org/0000-0001-9929-2725ДобрынинаЛ. А.DobrininaL. A.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

https://orcid.org/0000-0002-8726-8928ЧечеткинА. О.ChechetkinA. O.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

https://orcid.org/0000-0002-0274-9694КаршиеваА. Р.KarshievaA. R.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

https://orcid.org/0000-0002-7017-6728АнаньеваЛ. Ю.AnanievaL. Yu.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

https://orcid.org/0000-0001-6365-5555ПушкинаД. С.PushkinaD. S.

 Россия, 125367, Москва, Волоколамское шоссе, 80 

 80, Volokolamskoe Shosse, Moscow 125367, Russia 

ФГБНУ «Научный центр неврологии»РоссияResearch Center of NeurologyRussian Federation202116122021136142146Copyright © Belopasova A.V., Dobrinina L.A., Chechetkin A.O., Karshieva A.R., Ananieva L.Y., Pushkina D.S., 20212021Белопасова А.В., Добрынина Л.А., Чечеткин А.О., Каршиева А.Р., Ананьева Л.Ю., Пушкина Д.С.Belopasova A.V., Dobrinina L.A., Chechetkin A.O., Karshieva A.R., Ananieva L.Y., Pushkina D.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1720

 The article presents a case report of a patient with cardioembolic ischemic stroke (IS), which was the first clinical manifestation of  congenital atrial septal defect (ASD), asymptomatic until adulthood.  The issues of anatomical classification, restructuring of  intracardiac hemodynamics depending on the size and localization  of ASD, its role in the development of IS are discussed. The  diagnostic algorithm in patients with IS caused by paradoxical  embolism is described, the current possibilities of ASD treatment  and prevention of related disorders of cerebral circulation are  discussed. 

 В статье представлено описание пациентки с кардиоэмболическим ишемическим инсультом (ИИ), развитие которого стало первым клиническим проявлением существующего дефекта межпредсердной  перегородки (ДМПП), бессимптомно протекавшего до зрелого возраста. Рассмотрены вопросы анатомической классификации, перестройки  внутрисердечной гемодинамики в зависимости от размеров и локализации ДМПП, его роли в развитии ИИ. Описан алгоритм  обследования больных с парадоксальной эмболией церебральных  сосудов, обсуждаются современные возможности лечения ДМПП и  профилактика связанных с ними нарушений мозгового  кровообращения.  

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The authors declare that there are no conflicts of interest present.