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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2021-4-30-36</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1615</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Workplace stress and cognitive functions (a population based study of adults aged 25—44 years)</article-title><trans-title-group xml:lang="ru"><trans-title>Стресс на рабочем месте и когнитивные функции (популяционное исследование населения в возрасте 25-44 лет)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гафаров Валерий Васильевич.</p><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>Valery Vasilyevich Gafarov.</p><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суханов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhanov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630089, Новосибирск, ул. Б. Богаткова, 175/1.</p></bio><bio xml:lang="en"><p>175/1, Boris Bogatkov St., Novosibirsk 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины — филиал ФГБНУ «Федеральный исследовательский центр Институт цитологии и генетики СО РАН»; Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеваний</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center «Research Institute of Cytology and Genetics», Siberian Branch, Russian Academy of Sciences; Collaborative Laboratory of Cardiovascular Diseases Epidemiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины — филиал ФГБНУ «Федеральный исследовательский центр Институт цитологии и генетики СО РАН»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center «Research Institute of Cytology and Genetics», Siberian Branch, Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>13</day><month>08</month><year>2021</year></pub-date><volume>13</volume><issue>4</issue><fpage>30</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Gafarov V.V., Sukhanov A.V., Gromova E.A., Panov D.O., Denisova D.V., Gagulin I.V., Gafarova A.V., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Суханов А.В., Громова Е.А., Панов Д.О., Денисова Д.В., Гагулин И.В., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Sukhanov A.V., Gromova E.A., Panov D.O., Denisova D.V., Gagulin I.V., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1615">https://nnp.ima-press.net/nnp/article/view/1615</self-uri><abstract><sec><title>Objective</title><p>Objective: to investigate the effect of workplace stress on cognitive functions of younger men and women (25—44 years) in an open population of Novosibirsk.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. The study included a representative sample of Novosibirsk population aged 25—44 years (2013—2016 screening) within the budgetary theme №0541-2014-0004. We screened individuals aged 25—44years: 463 men, mean age 35.94±5.957years, and 546 women, mean age 36.17±5.997 years. Association of workplace stress with cognitive functions were assessed with standardized questions such as: «Has your specialty changed over the past 12 years?», «Do you like your job?» and «How do you rate your work responsibility over the past 12 months?». Cognitive evaluation during screening period included: A.R. Luria 10-words learning task (immediate and delayed recall), Burdon's test, exclusion of concepts «5th extra», animal naming test.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. We observed a decrease in semantic associations number among the respondents who did not change their occupation over the past year and among respondents who assess their work responsibility as «low». Verbal logical reasoning was lower in the respondents who assumed that they «did not like» or «did not like at all» their job and also assessed their work responsibility as «low». Auditory verbal shortterm memory, long-term memory, memorization productivity, and attention were worse in the participants who had either «insignificant» or «average» work responsibility.</p></sec><sec><title>Conclusion</title><p>Conclusion. Younger adults experiencing workplace stress have a decrease in cognitive functions.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цель исследования — изучить влияние стресса на рабочем месте на когнитивные функции (КФ) мужчин и женщин молодого возраста (25—44 лет) в открытой популяции г. Новосибирска.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Объектом исследования стала случайная репрезентативная выборка населения г. Новосибирска в возрасте 25—44 лет (скрининг 2013—2016 гг.) в рамках бюджетной темы №0541-2014-0004. Были обследованы лица в возрасте 25—44 лет: 463мужчины (средний возраст — 35,94±5,957гоДа) и 546 женщин (средний возраст — 36,17±5,997гоДа). Для оценки стресса на работе у участников скрининга исследовались ассоциации КФ с такими стандартизированными вопросами, как: «Изменилась ли Ваша специальность в течение последних 12 лет?», «Нравится ли Вам ваша работа?» и «Как Вы оцениваете ответственность своей работы в течение последних 12 месяцев?». Использовались тесты Для оценки состояния КФ в условиях скрининга: проба на запоминание 10 слов по А.Р. Лурия с последующим воспроизведением после интерферирующего задания, 1-й опыт пробы на запоминание 10 слов по А.Р. Лурия, корректурная проба, тест исключения понятий «5-й лишний», тест на речевую активность в виде называния животных за 1 мин (Animal Naming Test).</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Выявлено ухудшение числа семантически опосредуемых ассоциаций среди тех респондентов, у кого за прошедший год не произошла смена специальности, а также среди респондентов, оценивающих свою ответственность на работе как «низкую». Установлено ухудшение словесно-логического мышления среди тех участников исследования, кто полагал, что работа либо «не нравится», либо «совсем не нравится», а также что ответственность на работе «низкая». Определено снижение слухоречевой кратковременной памяти, долговременной памяти, продуктивности запоминания, а также ухудшение внимания среди лиц, испытывающих «незначительную» либо «среднюю» ответственность на рабочем месте.</p></sec><sec><title>Заключение</title><p>Заключение. В исследовании продемонстрировано ухудшение КФ у лиц молодого возраста, испытывающих стресс на рабочем месте.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>стресс на рабочем месте</kwd><kwd>когнитивная функция</kwd><kwd>когнитивные нарушения</kwd><kwd>популяция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>workplace stress</kwd><kwd>cognitive functions</kwd><kwd>cognitive impairment</kwd><kwd>population</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено в рамках бюджетной темы №0541-2014-0004.</funding-statement><funding-statement xml:lang="en">The study was performed within the framework of the budget theme, №0541-2014-0004.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Du Prel JB, Runeson-Broberg R, Westerholm P, et al. Work overcommitment: Is it a trait or a state? 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