References

nnp

Neurology, Neuropsychiatry, Psychosomatics

Неврология, нейропсихиатрия, психосоматика

2074-27112310-1342

"IMA-Press", LLC

10.14412/2074-2711-2021-2-123-129

nnp-1551

Research Article

REVIEWS

ОБЗОРЫ

Cognitive impairment in COVID-19: associations, pathogenesis and treatment questions

Когнитивные нарушения при COVID-19: взаимосвязь, патогенез и вопросы терапии

Головачева

В. А.

Golovacheva

V. A.

Россия, 119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya Str., Build. 2, Moscow 119991, Russia

xoxo.veronicka@gmail.com

Табеева

Г. Р.

Tabeeva

G. R.

Россия, 119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya Str., Build. 2, Moscow 119991, Russia

Кузнецов

И. В.

Kuznetsov

I. V.

Россия, 119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya Str., Build. 2, Moscow 119991, Russia

Университетская клиническая больница №3 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияDepartment of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Clinical Medicine InstituteRussian Federation

Университетская клиническая больница №3 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияUniversity Hospital №3, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation

2021

23042021

132123129

2021

Головачева В.А., Табеева Г.Р., Кузнецов И.В.

Golovacheva V.A., Tabeeva G.R., Kuznetsov I.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://nnp.ima-press.net/nnp/article/view/1551

Cognitive impairment (CI) can be neurological symptoms or complications of coronavirus disease 2019 (COVID-19). Among the pathogenetic mechanisms, the neurotropicity of the SARS- CoV-2 virus, endothelial dysfunction, coagulopathy, thrombus formation, systemic inflammatory reaction, the consequences of mechanical ventilation and drug sedation are considered. Treatment strategies for COVID-19 patients with CI have not yet been developed. The following tactics of patient management is advisable: prevention of re-infection, assessment and correction of the emotional state, treatment of cardiovascular diseases. The possibilities of vinpocetine in the treatment of CI after COVID-19 are discussed.

Когнитивные нарушения (КН) могут быть неврологическими симптомами или осложнениями коронавирусной болезни 2019 (COVID-19). Среди патогенетических механизмов рассматриваются нейротропность вируса SARS-CoV-2, эндотелиальная дисфункция, коагулопатия, тромбообразование, системная воспалительная реакция, последствия искусственной вентиляции легких и медикаментозной седации. Стратегии лечения пациентов, перенесших COVID-19 и имеющих КН, еще не разработаны. Целесообразна следующая тактика ведения пациентов: предупреждение повторного заражения, оценка и коррекция эмоционального состояния, лечение сердечно-сосудистых заболеваний. Обсуждаются возможности винпоцетина в лечении КН после COVID-19.

COVID-19когнитивные нарушениялечениевинпоцетин

COVID-19cognitive impairmenttreatmentvinpocetine

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The authors declare that there are no conflicts of interest present.