nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2021-1-126-130nnp-1519Research ArticleREVIEWSОБЗОРЫCognitive impairment in COVID-19 survivorsКогнитивные нарушения у пациентов, перенесших COVID-19ОстроумоваТ. М.OstroumovaT. M.

Татьяна Максимова Остроумова

119991, Москва, ул. Трубецкая, 8, стр. 2

Tatiana Maksimovna Ostroumova

8, Trubetskaya St., Build. 2, Moscow 119021

t.ostroumova3@gmail.comЧерноусовП. А.ChernousovP. A.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119021

КузнецовИ. В.KuznetsovI. V.

119991, Москва, ул. Трубецкая, 8, стр. 2

8, Trubetskaya St., Build. 2, Moscow 119021

ФГБОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation202118022021131126130Copyright © Ostroumova T.M., Chernousov P.A., Kuznetsov I.V., 20212021Остроумова Т.М., Черноусов П.А., Кузнецов И.В.Ostroumova T.M., Chernousov P.A., Kuznetsov I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1519

The neurological manifestations of the novel coronavirus COVID-19 infection caused by SARS-CoV-2 are extremely diverse. At the same time, there is currently very little data on the neurological complications of COVID-19. There are more and more publications on the presence of a complication, such as cognitive impairment (CI). The latter is analyzed in patients with COVID-19 during their hospital stay and later on. The paper discusses possible mechanisms, including a hyperinflammatory state (cytokine storm), coagulopathy, and the neurotropic effect of the virus, which may play a role in the development of CI in patients with COVID-19. It considers management tactics for patients with CI in the presence of coronavirus infection and the possibility of their correction with citicoline (Noocil®).

Неврологические проявления новой коронавирусной инфекции COVID-19, вызываемой коронавирусом SARS-CoV-2, чрезвычайно многообразны. При этом в настоящее время имеется крайне мало данных о неврологических осложнениях перенесенного COVID-19. Появляется все больше публикаций о наличии такого осложнения, как когнитивные нарушения (КН). Анализируются КН у пациентов на фоне COVID-19 в период пребывания в стационаре и в дальнейшем. Обсуждаются возможные механизмы, которые могут играть роль в развитии КН у пациентов с COVID-19, в том числе гипервоспалительное состояние (цитокиновый шторм), коагулопатия, нейротропное действие вируса. Рассмотрена тактика ведения пациентов с КН в условиях коронавирусной инфекции и возможности их коррекции цитиколином (Нооцил®).

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The authors declare that there are no conflicts of interest present.