nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2020-6-104-109nnp-1478Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯNormal pressure hydrocephalus and cerebral amyloid angiopathy: a set of diseases or the unity of pathogenesis?Нормотензивная гидроцефалия и церебральная амилоидная ангиопатия: комбинация заболеваний или единство патогенеза?МенделевичЕ. Г.MendelevichE. G.

Елена Геннадиевна Менделевич

Кафедра неврологии и реабилитации

420012, Казань, ул. Бутлерова, 49

Elena Gennadievna Mendelevich

Department of Neurology and Rehabilitation

49, Butlerov St., Kazan 420012

emendel@mail.ruФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииРоссияKazan State Medical University, Ministry of Health of RussiaRussian Federation202012122020126104109Copyright © Mendelevich E.G., 20202020Менделевич Е.Г.Mendelevich E.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1478

Idiopathic normal pressure hydrocephalus (NPH) is cerebral ventriculomegaly characterized by a wide range of controversial issues related to the prevalence of the disease, the mechanisms of its development, and nosological independence. Developing in old age, NTH is often concurrent with other neurodegenerative or cerebrovascular diseases, posing certain diagnostic difficulties. The paper describes a clinical case of a patient initially diagnosed with NTH, followed by amyloid angiopathy signs detected during magnetic resonance imaging after bypass surgery. It discusses the diagnostic features of NTH and amyloid angiopathy and the possible common mechanisms of these diseases.

Нормотензивная идиопатическая гидроцефалия (НТГ) – это вентрикуломегалия головного мозга, характеризующаяся широким кругом дискуссионных вопросов, касающихся распространенности заболевания, механизмов его развития и нозологической самостоятельности. Развиваясь в пожилом возрасте, НТГ часто сочетается с другими нейродегенеративными или цереброваскулярными патологиями, что имеет определенные диагностические сложности. Приводится клиническое наблюдение больного с первоначальным диагнозом НТГ и последующим появлением признаков амилоидной ангиопатии по данным магнитно-резонансной томографии после шунтирующей операции. Обсуждаются особенности диагностики НТГ и амилоидной ангиопатии и возможность общих механизмов этих заболеваний.

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The authors declare that there are no conflicts of interest present.