nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2020-6-83-89nnp-1475Research ArticleREVIEWSОБЗОРЫContemporary views of the mechanisms for development of myofascial pain syndrome and its treatment strategiesСовременные представления о механизмах формирования и стратегиях лечения миофасциального болевого синдромаТабееваГ. Р.TabeevaG. R.

Гюзяль Рафкатовна Табеева

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11, стр. 1

Gyuzyal Rafkatovna Tabeeva

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Build. 1, Moscow 119021

grtabeeva@gmail.comКирьяноваЕ. А.KiryanovaE. A.

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11, стр. 1

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Build. 1, Moscow 119021

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation2020121220201268389Copyright © Tabeeva G.R., Kiryanova E.A., 20202020Табеева Г.Р., Кирьянова Е.А.Tabeeva G.R., Kiryanova E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1475

Myofascial pain syndrome (MFPS) is a regional pain syndrome that can be diagnosed in any age group and is characterized by the presence of a trigger point in the muscle involved in the pathological process. Clarifying the molecular mechanisms of trigger point formation and dysregulation of specific skeletal muscle proteins is important to understand the causes of abnormal sarcomere contraction observed in myofascial pain. Wide variability in using the diagnostic criteria in some cases leads to the impossibility of performing a meta-analysis of the data; in this connection, the search for the gold standard for MFPS diagnosis is actively underway. At the moment, a special clinical examination is of paramount diagnostic value. The paper considers various treatment options for myofascial pain and discusses the priority importance of using nonsteroidal anti-inflammatory drugs and muscle relaxants, as well as non-drug therapies.

Миофасциальный болевой синдром (МФБС) – это регионарный болевой синдром, который может диагностироваться в любой возрастной группе и характеризуется присутствием триггерной точки в вовлеченной в патологический процесс мышце. Уточнение молекулярных механизмов формирования триггерных точек и дизрегуляции специфических белков скелетной мускулатуры важно для понимания причин аномального сокращения саркомеров, наблюдаемого при миофасциальной боли. Широкая вариабельность применения диагностических критериев в отдельных случаях приводит к невозможности проведения метаанализа данных, в связи с чем активно ведется поиск «золотого стандарта» диагностики МФБС. На данный момент первостепенное диагностическое значение имеет специальный клинический осмотр. В статье рассматриваются различные варианты лечения миофасциальной боли, обсуждается приоритетное значение применения нестероидных противовоспалительных препаратов и миорелаксантов, а также методов немедикаментозной терапии.

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The authors declare that there are no conflicts of interest present.