nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2020-5-84-91nnp-1452Research ArticleREVIEWSОБЗОРЫThe etiology, manifestations, and therapy of chronic cerebrovascular diseasesВопросы этиологии, проявлений и терапии хронических цереброваскулярных заболеванийГоголеваА. Г.GogolevaA. G.

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11, стр. 1

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Build. 1, Moscow 119021

ЗахаровВ. В.ZakharovV. V.

Владимир Владимирович Захаров

Кафедра нервных болезней и нейрохирургии

119021, Москва, ул. Россолимо, 11, стр. 1

Vladimir V. Zakharov

Department of Nervous System Diseases and Neurosurgery

11, Rossolimo St., Build. 1, Moscow 119021

zakharovenator@gmail.comИнститут клинической медицины им. Н.В. Склифосовского ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияN.V. Sklifosovsky Institute of Clinical Medicine I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaRussian Federation2020251020201258491Copyright © Gogoleva A.G., Zakharov V.V., 20202020Гоголева А.Г., Захаров В.В.Gogoleva A.G., Zakharov V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1452

The paper presents the current etiopathogenetic classification of chronic cerebrovascular diseases (CVD) and discusses the role of hypertension, cerebral amyloid angiopathy, and genetically determined syndromes in the development of this pathological condition. It gives recommendations for the neuroradiological diagnosis of chronic CVD in accordance with the international standards. The paper discusses the clinical manifestations of chronic CVD, primarily vascular cognitive impairment. It discusses international guidelines for the examination and treatment of patients with chronic CVD, as well as the rules for stroke prevention in this patient cohort. The possibilities of pathogenetically based therapy in decreasing the severity of vascular cognitive impairment in the presence of chronic CVD are also highlighted.

В статье представлена современная этиопатогенетическая классификация хронических цереброваскулярных заболеваний (ЦВЗ), обсуждается роль артериальной гипертензии, церебральной амилоидной ангиопатии, генетически детерминированных синдромов в развитии этого патологического состояния. Даются рекомендации по нейрорадиологической диагностике хронических ЦВЗ в соответствии с международными стандартами. Обсуждаются клинические проявления хронических ЦВЗ, в первую очередь сосудистые когнитивные нарушения. Приводятся международные рекомендации по обследованию и лечению пациентов с хроническими ЦВЗ, правила профилактики инсультов в данной когорте больных. Освещаются также возможности патогенетически обоснованной терапии в отношении уменьшения выраженности сосудистых когнитивных нарушений на фоне хронической цереброваскулярной патологии.

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The authors declare that there are no conflicts of interest present.