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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2020-4-25-31</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1407</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group></article-categories><title-group><article-title>Drug-induced headache: an analysis of therapeutic strategies</article-title><trans-title-group xml:lang="ru"><trans-title>Лекарственно-индуцированная головная боль: анализ терапевтических стратегий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мербаум</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Merbaum</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии</p><p>2119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Табеева</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Tabeeva</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гюзяль Рафкатовна Табеева</p><p>Кафедра нервных болезней и нейрохирургии</p><p>2119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Guzyal Rafkatovna Tabeeva</p><p>Department of Nervous System Diseases and Neurosurgery</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><email xlink:type="simple">grtabeeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии</p><p>2119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery</p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2020</year></pub-date><volume>12</volume><issue>4</issue><fpage>25</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Merbaum P.A., Tabeeva G.R., Sergeev A.V., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Мербаум П.А., Табеева Г.Р., Сергеев А.В.</copyright-holder><copyright-holder xml:lang="en">Merbaum P.A., Tabeeva G.R., Sergeev A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1407">https://nnp.ima-press.net/nnp/article/view/1407</self-uri><abstract><p>To manage patients with drug-induced headache (DIH) is an unsolved problem of modern neurology in developed countries, since DIH is becoming a common cause of temporary disability and leads to lower quality of life in patients. Patients with primary headache (for example, those with tension headache or migraine) frequently take symptomatic headache relief medications uncontrollably, which can result in the higher frequency and intensity of DIH episodes. In turn, new headache attacks make the patients take the increasing number of symptomatic medications, which leads to the development of DIH.The International Classification of Headache Disorders, 3 rd Edition, defines DIH as a distinct form of secondary headache. To date, there is no consensus on the tactics of DIH treatment and prevention. The paper discusses different approaches to DIH prevention and treatment, the effectiveness and appropriateness of their use, as well as factors influencing illness course and possible outcomes. Particular attention is paid to the management of patients during the withdrawal period, risk factors for DIH recurrences, and ways of their prevention.</p></abstract><trans-abstract xml:lang="ru"><p>Ведение пациентов с лекарственно-индуцированной головной болью (ЛИГБ) – это нерешенная проблема современной неврологии в развитых странах, так как ЛИГБ становится частой причиной временной утраты трудоспособности и приводит к снижению качества жизни пациентов. Пациенты с первичной головной болью (например, страдающие головной болью напряжения или мигренью) нередко бесконтрольно применяют симптоматические препараты для купирования головной боли, что может привести к увеличению частоты и интенсивности ее эпизодов. В свою очередь, новые приступы головной боли провоцируют пациентов на употребление еще большего количества симптоматических препаратов, что приводит к формированию ЛИГБ.В Международной классификации головных болей 3-го пересмотра ЛИГБ определяется как отдельная форма вторичной головной боли. На сегодняшний день нет единого мнения о тактике лечения и профилактики ЛИГБ. В статье обсуждаются различные подходы к профилактике и терапии ЛИГБ, их эффективность и целесообразность применения, а также факторы, влияющие на течение заболевания и возможные исходы. Особое внимание уделено ведению пациентов в период отмены, факторам риска рецидивов ЛИГБ и способам их предотвращения.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лекарственно-индуцированная головная боль</kwd><kwd>образовательная беседа</kwd><kwd>терапия отмены</kwd><kwd>профилактическая терапия лекарственно-индуцированной головной боли</kwd><kwd>факторы риска</kwd><kwd>рефрактерная лекарственно-индуцированная головная боль</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>drug-induced headache</kwd><kwd>educational talk</kwd><kwd>withdrawal therapy</kwd><kwd>prevention therapy for drug-induced headache</kwd><kwd>risk factors</kwd><kwd>druginduced refractory headache</kwd><kwd>prognosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bendtsena L, Eversb S, Lindec M, et al. 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