nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2020-1S-44-47nnp-1402Research ArticleREVIEWSОБЗОРЫNervous system damage in COVID-19 with an emphasis on the management of patients with multiple sclerosisПоражение нервной системы при инфекции COVID-19 с акцентом на ведение пациентов с рассеянным склерозомБойкоА. Н.BoykoA. N.

Кафедра неврологии, нейрохирургии и медицинской генетикиотдел нейроиммунологии

117997, Москва, ул. Островитянова, 1; 117997, Москва, ул. Островитянова, 1, стр. 10;

Department of Neurology, Neurosurgery, and Medical Genetics;Department of Neuroimmunology

1, Ostrovityanov St, Moscow 117997; 1, Ostrovityanov St, Build. 10, Moscow 117997;

boykoan13@gmail.comСиверцеваС. А.SivertsevaS. A.

625000, Тюмень, ул. Юрия Семовских, 8/1;

8/1, Yuri Semovskikh St., Tyumen 625000;

СпиринН. Н.SpirinN. N.

150000, Ярославль, ул. Революционная, 5

5, Revolyutsionnaya St., Yaroslavl 150000

ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России; ФГБУ «Федеральный центр мозга и нейротехнологий» ФМБА;РоссияN.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; Federal Center for the Brain and Neurotechnologies, Federal Medical Biological Agency of Russia;Russian FederationТюменский областной центр рассеянного склероза;РоссияTyumen Regional Multiple Sclerosis Center;Russian FederationФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава РоссииРоссияYaroslavl State Medical University, Ministry of Health of RussiaRussian Federation202005082020121SСпецвыпуск: рассеянный склероз4447Copyright © Boyko A.N., Sivertseva S.A., Spirin N.N., 20202020Бойко А.Н., Сиверцева С.А., Спирин Н.Н.Boyko A.N., Sivertseva S.A., Spirin N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1402

The main target for COVID-19 is the lung with the development of acute respiratory failure. But the virus also displays tropism to the central nervous, muscle, and immune systems. The paper gives the data available in the literature on nervous system damage and the characteristics of clinical and magnetic resonance imaging manifestations of brain damage in COVID-19. Among the neurological symptoms of COVID-19, there may be stroke, encephalitis, and neuropathy. An account is given of the features of multiple sclerosis patient management during the COVID-19 pandemic depending on the risk of developing coronavirus infection.

Основной мишенью при CОVID-19 являются легкие с развитием острого синдрома респираторной недостаточности. Но вирус также тропен к ЦНС, мышечной и иммунной системам. Приведены данные литературы о поражении нервной системы, а также особенности клинических и выявляемых при магнитно-резонансной томографии проявлений поражения головного мозга при COVID-19. Среди неврологических симптомов COVID-19 могут быть инсульт, энцефалит и невропатии. Описаны особенности ведения пациентов с рассеянным склерозом во время пандемии COVID-19 в зависимости от риска развития коронавирусной инфекции.

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The authors declare that there are no conflicts of interest present.