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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2020-3-69-74</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1368</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Cervical dystonia: non-motor aspects</article-title><trans-title-group xml:lang="ru"><trans-title>Цервикальная дистония: немоторные аспекты</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дружинина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Druzhinina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дружинина Оксана Аркадьевна.</p><p>630099, Новосибирск, ул. Серебренниковская, 42.</p></bio><bio xml:lang="en"><p>Oksana Arkadyevna Druzhinina.</p><p>42, Serebrennikovskaya St., Novosibirsk 630099.</p></bio><email xlink:type="simple">oxi-novosib@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>2, Moskovsky High Road, Tomsk 634050.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шперлинг</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Shperling</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630099, Новосибирск, ул. Серебренниковская, 42.</p></bio><bio xml:lang="en"><p>42, Serebrennikovskaya St., Novosibirsk 630099.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новотный</surname><given-names>Д. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Novotnyi</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630099, Новосибирск, ул. Серебренниковская, 42.</p></bio><bio xml:lang="en"><p>42, Serebrennikovskaya St., Novosibirsk 630099.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая поликлиника №1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Polyclinic One</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Областной центр экстрапирамидных заболеваний с кабинетом ботулинотерапии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Center for Extrapyramidal Diseases with Botulinum Toxin Therapy Room</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>25</day><month>06</month><year>2020</year></pub-date><volume>12</volume><issue>3</issue><fpage>69</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Druzhinina O.A., Zhukova N.G., Shperling L.P., Novotnyi D.A., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Дружинина О.А., Жукова Н.Г., Шперлинг Л.П., Новотный Д.A.</copyright-holder><copyright-holder xml:lang="en">Druzhinina O.A., Zhukova N.G., Shperling L.P., Novotnyi D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1368">https://nnp.ima-press.net/nnp/article/view/1368</self-uri><abstract><p>Cervical dystonia (CD) is manifested by violent, often painful movements of the neck muscles with the abnormal head and/or neck postures being formed. Disease progression leads to disability of patients. The clinical picture of the disease is characterized by a concurrence of motor and non-motor disorders.</p><sec><title>Objective</title><p>Objective: to analyze the features of non-motor manifestations (pain, asthenia, anxiety, depression, sleep disorders) and quality of life (QOL) in patients with CD.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. A total of110 patients (31 men and 89 women) aged 27—82years (mean age, 54.4±12.4 years) with CD (a study group) were examined. A control group consisted of 50 patients (16 men and 34 women) aged 25—82 years (mean age, 51.7±14.8 years) with cervical dorsalgia. Clinical, neurological, and neuropsychological examinations were made according to validated questionnaires. The investigators assessed pain using a visual analogue scale, anxiety and depressive disorders by the Hospital Anxiety and Depression Scale (HADS), asthenia by the Multidimensional Fatigue Inventory (MFI-20) and the scale of asthenic state (SAS), night sleep quality by the Pittsburg Sleep Quality Index (PSQI), and quality of life by the 36-Item Short Form Survey (SF-36).</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The patients with CD showed a high incidence ofnon-motor disturbances: pain (98%), asthenia (90%), nocturnal sleep disorders (80%), anxiety (53%), and depression (48%). Non-motor symptoms were statistically significantly more obvious in the patients with CD than in those with cervical dorsalgia. The QOL indicators in CD were statistically significantly reduced in all physical and psychological parameters.</p></sec><sec><title>Conclusion</title><p>Conclusion. Non-motor manifestations occupy an important place in the clinical picture of CD, substantially reducing the physical and psychological aspects of QOL in the patients.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цервикальная дистония (ЦД) проявляется насильственными, часто болезненными движениями мышц шеи с формированием патологической позы головы и/или шеи. Прогрессирование заболевания приводит к инвалидизации больных. Для клинической картины заболевания характерно сочетание двигательных и немоторных нарушений.</p><p>Цель исследования — анализ особенностей немоторных проявлений (боль, астения, тревога, депрессия, нарушения сна) и качества жизни (КЖ) у пациентов с ЦД.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Обследовано 110 пациентов с ЦД (31 мужчина и 89 женщин) в возрасте 27—82 лет (средний возраст 54,4±12,4 года; основная группа). Группу контроля составили 50 пациентов с цервикальный дорсалгией (16 мужчин и 34 женщин) в возрасте 25—82лет (средний возраст 51,7±14,8 года). Было проведено клинико-неврологическое, нейропсихологическое обследование с применением валидированных опросников. Боль оценивали по визуальной аналоговой шкале; тревожно-депрессивное расстройство — по HADS; астению — по MFI-20 и шкале астенического состояния; качество ночного сна — по PSQI; качество жизни — по SF-36.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Выявлена высокая встречаемость немоторных нарушений у пациентов с ЦД: боль — у 98%, астения — у 90%, нарушения ночного сна — у 80%, тревога — у 53%, депрессия — у 48%. Немоторные симптомы у больных с ЦД были статистически значимо более выраженными, чем у пациентов группы цервикальной дорсалгии. КЖ при ЦД было статистически значимо снижено по всем физическим и психологическим параметрам.</p></sec><sec><title>Заключение</title><p>Заключение. Немоторные проявления занимают важное место в клинической картине ЦД, существенно снижая физические и психологические аспекты КЖ больных.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>цервикальная дистония</kwd><kwd>немоторные симптомы</kwd><kwd>качество жизни</kwd><kwd>коморбидность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cervical dystonia</kwd><kwd>non-motor symptoms</kwd><kwd>quality of life</kwd><kwd>comorbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Залялова ЗА, Хафизова ИФ, Хаятова ЗГ. Патофизиологические основы реабилитации при цервикальной дистонии. Фараматека. 2017:(15):7-15.</mixed-citation><mixed-citation xml:lang="en">Zalyalova ZA, Khafizova IF, Khayatova ZG. Pathophysiological bases of rehabilitation for cervical dystonia. Faramateka. 2017:(15):7-15. 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