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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2020-2-72-78</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1307</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Patent foramen ovale-related stroke: diagnostic approaches and the possibility of endovascular prophylaxis (clinical cases and literature review)</article-title><trans-title-group xml:lang="ru"><trans-title>Инсульт, ассоциированный с открытым овальным окном: подходы к диагностике и возможности эндоваскулярной профилактики (клинические наблюдения и обзор литературы)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулеш</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulesh</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 614990, Пермь, ул. Петропавловская, 26 </p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990 </p></bio><email xlink:type="simple">aleksey.kulesh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Огнерубов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ognerubov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мехряков</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mekhryakov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 614990, Пермь, ул. Петропавловская, 26 </p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меркулов</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Merkulov</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сыромятникова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Syromyatnikova</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 614990, Пермь, ул. Петропавловская, 26 </p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенко</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshchenko</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самко</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Samko</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестаков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракулова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakulova</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России;&#13;
ГАУЗ ПК «Городская клиническая больница №4»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia;&#13;
City Clinical Hospital Four</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Cardiology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>18</day><month>04</month><year>2020</year></pub-date><volume>12</volume><issue>2</issue><fpage>72</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kulesh A.A., Ognerubov D.V., Mekhryakov S.A., Merkulov E.V., Syromyatnikova L.I., Tereshchenko A.S., Samko A.N., Shestakov V.V., Karakulova Y.V., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кулеш А.А., Огнерубов Д.В., Мехряков С.А., Меркулов Е.В., Сыромятникова Л.И., Терещенко А.С., Самко А.Н., Шестаков В.В., Каракулова Ю.В.</copyright-holder><copyright-holder xml:lang="en">Kulesh A.A., Ognerubov D.V., Mekhryakov S.A., Merkulov E.V., Syromyatnikova L.I., Tereshchenko A.S., Samko A.N., Shestakov V.V., Karakulova Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1307">https://nnp.ima-press.net/nnp/article/view/1307</self-uri><abstract/><trans-abstract xml:lang="ru"/><kwd-group xml:lang="ru"><kwd>открытое овальное окно</kwd><kwd>криптогенный инсульт</kwd><kwd>парадоксальная эмболия</kwd><kwd>эндоваскулярная окклюзия</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>patent foramen ovale</kwd><kwd>cryptogenic stroke</kwd><kwd>paradoxical embolism</kwd><kwd>endovascular occlusion</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Giblett J, Abdul-Samad O, Shapiro L, et al. 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