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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2019-4-14-21</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1203</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group></article-categories><title-group><article-title>Cryptogenic stroke</article-title><trans-title-group xml:lang="ru"><trans-title>Криптогенный инсульт</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулеш</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulesh</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>614990, Пермь, ул. Петропавловская, 26;</p><p>614107, Пермь, ул. Ким, 2</p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990;</p><p>2, Kim St., Perm 614107</p></bio><email xlink:type="simple">aleksey.kulesh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробаха</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobakha</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>614990, Пермь, ул. Петропавловская, 26;</p><p>614107, Пермь, ул. Ким, 2</p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990;</p><p>2, Kim St., Perm 614107</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестаков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>614990, Пермь, ул. Петропавловская, 26</p></bio><bio xml:lang="en"><p>26, Petropavlovskaya St., Perm 614990</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России;&#13;
ГАУЗ ПК «Городская клиническая больница №4»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia;&#13;
City Clinical Hospital Four</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>07</day><month>12</month><year>2019</year></pub-date><volume>11</volume><issue>4</issue><fpage>14</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kulesh A.A., Drobakha V.E., Shestakov V.V., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кулеш А.А., Дробаха В.Е., Шестаков В.В.</copyright-holder><copyright-holder xml:lang="en">Kulesh A.A., Drobakha V.E., Shestakov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1203">https://nnp.ima-press.net/nnp/article/view/1203</self-uri><abstract><p>The paper considers the epidemiology and general etiological characteristics of cryptogenic stroke (CS). It discusses the concept of embolic stroke with an unknown source of embolism. It also characterizes the most significant causes of CS, such as paroxysmal atrial fibrillation, atrial cardiopathy, aortic atheroma, non-stenotic cerebral atherosclerotic plaques, and malignant neoplasms. The paper describes approaches to the diagnosis and secondary prevention of CS and proposes etiological and neuroimaging diagnostic algorithms for CI. Clinical cases are also presented.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассматриваются эпидемиология и общая этиологическая характеристика криптогенного инсульта (КИ). Обсуждается концепция эмболического инсульта с неизвестным источником эмболии. Охарактеризованы наиболее значимые причины КИ, такие как пароксизмальная форма фибрилляции предсердий, предсердная кардиопатия, атерома аорты, нестенозирующие атеросклеротические бляшки церебральных сосудов и злокачественные новообразования. Описаны подходы к диагностике и вторичной профилактике КИ, предложены этиологический и нейровизуализационный диагностические алгоритмы при КИ. Представлены также клинические наблюдения.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>криптогенный инсульт</kwd><kwd>атерома дуги аорты</kwd><kwd>фибрилляция предсердий</kwd><kwd>рак</kwd><kwd>диагностика</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cryptogenic stroke</kwd><kwd>aortic arch atheroma</kwd><kwd>atrial fibrillation</kwd><kwd>cancer</kwd><kwd>diagnosis</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nouh A, Hussain M, Mehta T, Yaghi S. Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice. 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