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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2019-3-63-68</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1175</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Back pain and osteoporosis</article-title><trans-title-group xml:lang="ru"><trans-title>Боль в спине и остеопороз</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исайкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaikin</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии,</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery, </p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><email xlink:type="simple">alexisa68@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исайкина</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaikina</surname><given-names>O. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>101990, Москва, Петроверигский пер., 10, стр. 3</p></bio><bio xml:lang="en"><p>10, Petroverigsky Lane, Build. 3, Moscow 101990</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шадыжева</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shadyzheva</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии,</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery, </p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шор</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shor</surname><given-names>Yu. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии,</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery, </p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Качановский</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kachanovsky</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нервных болезней и нейрохирургии,</p><p>119021, Москва, ул. Россолимо, 11, стр. 1</p></bio><bio xml:lang="en"><p>Department of Nervous System Diseases and Neurosurgery, </p><p>11, Rossolimo St., Build. 1, Moscow 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский медицинский университет им. И.М. Сеченова (Сеченовский университет)»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр профилактической медицины» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Preventive Medicine, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>10</month><year>2019</year></pub-date><volume>11</volume><issue>3</issue><fpage>63</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Isaikin A.I., Isaikina O.Y., Shadyzheva T.I., Shor Y.M., Kachanovsky M.S., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Исайкин А.И., Исайкина О.Ю., Шадыжева Т.И., Шор Ю.М., Качановский М.С.</copyright-holder><copyright-holder xml:lang="en">Isaikin A.I., Isaikina O.Y., Shadyzheva T.I., Shor Y.M., Kachanovsky M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1175">https://nnp.ima-press.net/nnp/article/view/1175</self-uri><abstract><p>The aging process is accompanied by a structural change and a decrease in the functional activity of organs and tissues, including the bone, with the development of osteoporosis (OP).</p><sec><title>Objective</title><p>Objective: to assess the characteristics of pain syndrome in OP patients with nonspecific chronic vertebrogenic lumbar ischialgia (CLI).</p></sec><sec><title>Patients and methods</title><p>Patients and methods. Sixty elderly patients with CLI in the presence and absence of OP were examined. All the patients underwent dual-energy X-ray absorptiometry and ultrasound to diagnose the degree of OP and spinal deformity; a flexible rod was used according to the method described by M.A. Kathleen to estimate the angle of kyphosis, lordosis, and scoliosis. The investigators determined pain intensity by a numerical rating scale, the presence of a neuropathic pain component by the DN4 pain scale, the level of anxiety and depression by the Hospital Anxiety and Depression Scale, cognitive status by the Montreal Cognitive Function Rating Scale, the degree of disability by the Oswestry questionnaire, and quality of life by the SF-12 Health Survey.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Our study showed that OP alone is not a cause of CLI in elderly patients. There were no statistically significant differences in the sources and intensity of pain, the degree of anxiety and depressive disorders, impaired quality of life, cognitive status, and degree of disability in patients with chronic lumbar pain syndrome in the presence and absence of OP. Vertebral deformity resulting from OP leads mainly to an obvious poor posture with an increase in thoracic kyphosis, straightening of lumbar lordosis, and S-curve lumbar and thoracic scoliosis, which can also cause secondary muscle spasm.</p><p>Patients with back pain in the presence of OP are treated in accordance with the general principles of management of patients with non-specific back pain, but taking into account the underlying disease. The paper presents current recommendations for the treatment of nonspecific back pain, for the management of patients with OP, as well as the updated clinical recommendations for the prevention of fractures in OP and osteopenia.</p></sec><sec><title>Conclusion</title><p>Conclusion. Patients with OP are noted to have predominantly chronic musculoskeletal pain in the presence of severe spinal deformity, but the level of this evidence is very low. The features of pain syndrome in patients with nonspecific vertebrogenic chronic lumbar ischialgia in the presence of OP call for further investigations. </p></sec></abstract><trans-abstract xml:lang="ru"><p>Процесс старения сопровождается изменением структуры и снижением функциональной активности органов и тканей, в том числе костной, с развитием остеопороза (ОП).</p><p>Цель исследования – оценка особенностей болевого синдрома у пациентов с вертеброгенной неспецифической хронической люмбоишиалгией (ХЛ), имеющих ОП.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Обследовано 60 пожилых пациентов с ХЛ с наличием ОП и без такового. Всем больным выполняли двухэнергетическую рентгеновскую абсорбциометрию и УЗИ для диагностики степени ОП и деформации позвоночника; для оценки угла кифоза, лордоза и сколиоза использовали гибкий стержень по методике М.А. Katbleen. Интенсивность боли определяли по числовой рейтинговой шкале, наличие невропатического компонента – по шкале DN-4, уровень тревожности и депрессии – по госпитальной шкале тревоги и депрессии, когнитивный статус – по Монреальской шкале оценки когнитивных функций, степень нарушения жизнедеятельности – по шкале Освестри, качество жизни – по шкале SF-12.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В нашем исследовании показано, что ОП сам по себе не является причиной ХЛ у пожилых пациентов. Не получено статистически значимых различий в источниках и интенсивности боли, степени тревожно-депрессивных расстройств, нарушения качества жизни, когнитивного статуса и степени инвалидизации у пациентов с хроническим поясничным болевым синдромом с наличием и отсутствием ОП. Деформация позвонков в результате ОП приводит в основном к выраженным нарушениям осанки с увеличением грудного кифоза, сглаживанию поясничного лордоза и S-образному пояснично-грудному сколиозу, что также может быть причиной вторичного мышечного спазма. Лечение пациентов с болью в спине при наличии ОП проводят в соответствии с общими принципами ведения больных с неспецифической болью в спине, но с учетом основного заболевания. Представлены современные рекомендации по лечению неспецифической боли в спине, по ведению пациентов с ОП, а также обновленные клинические рекомендации для предотвращения переломов при ОП и остеопении.</p></sec><sec><title>Заключение</title><p>Заключение. У пациентов с ОП отмечается преимущественно скелетно-мышечная хроническая боль на фоне грубой деформации позвоночника, но уровень доказательности этих данных очень низкий. Особенности болевого синдрома у пациентов с вертеброгенной неспецифической ХЛ на фоне ОП требуют дальнейшего изучения. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>боль в пояснице</kwd><kwd>остеопороз</kwd><kwd>компрессионные переломы позвонков</kwd><kwd>мультидисциплинарный подход</kwd><kwd>лечебная гимнастика</kwd><kwd>шкала FRAX</kwd><kwd>денситометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>low back pain</kwd><kwd>osteoporosis</kwd><kwd>vertebral compression fractures</kwd><kwd>multidisciplinary approach</kwd><kwd>therapeutic exercises</kwd><kwd>FRAX scale</kwd><kwd>densitometry</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Публикация статьи поддержана ОАО «Гедеон Рихтер Фарма».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Podichetty VK, Mazanec DJ, Biscup RS. 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