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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2019-3S-38-45</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1132</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИ</subject></subj-group></article-categories><title-group><article-title>Migraine and other headaches in transient ischemic attacks</article-title><trans-title-group xml:lang="ru"><trans-title>Мигрень и другие виды головной боли при транзиторных ишемических атаках</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>Е. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>620028, Екатеринбург, ул. Репина, 3;</p><p>620000, Екатеринбург, ул. Фурманова, 67;</p><p>620109, Екатеринбург, Заводская улица, 29</p></bio><bio xml:lang="en"><p>3, Repin St., Yekaterinburg 620028;</p><p>67, Furmanov St., Yekaterinburg 262000;</p><p>29, Zavodskaya St., Yekaterinburg 620109</p></bio><email xlink:type="simple">cosmos@k66.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гурарий</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurary</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>620028, Екатеринбург, ул. Репина, 3;</p><p>620109, Екатеринбург, Заводская улица, 29</p></bio><bio xml:lang="en"><p>3, Repin St., Yekaterinburg 620028;</p><p>29, Zavodskaya St., Yekaterinburg 620109</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олесен</surname><given-names>Ес</given-names></name><name name-style="western" xml:lang="en"><surname>Olesen</surname><given-names>J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра неврологии, </p><p>Copenhagen, Nordre Ringvej 57, 2600, Glostrup</p></bio><bio xml:lang="en"><p>Nordre Ringvej 57, Glostrup, 2600, Copenhagen</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра скорой медицинской помощи ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России;&#13;
Международный центр лечения головной и лицевой боли «Европа–Азия»;&#13;
ООО МО «Новая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Emergency Medical Care, Ural State Medical University, Ministry of Health of Russia;&#13;
International Headache and Facial Pain Center “Europe-Asia”;&#13;
New Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра скорой медицинской помощи ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России;&#13;
ООО МО «Новая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Emergency Medical Care, Ural State Medical University, Ministry of Health of Russia;&#13;
New Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Университет Копенгагена, Датский центр лечения головных болей</institution><country>Дания</country></aff><aff xml:lang="en"><institution>Department of Neurology,Danish Headache Center, University of Copenhagen</institution><country>Denmark</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2019</year></pub-date><volume>11</volume><issue>3S</issue><issue-title>Спецвыпуск: когнитивные нарушения, цереброваскулярные заболевания</issue-title><fpage>38</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Lebedeva E.R., Gurary N.M., Olesen J., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Лебедева Е.Р., Гурарий Н.М., Олесен Е.</copyright-holder><copyright-holder xml:lang="en">Lebedeva E.R., Gurary N.M., Olesen J.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1132">https://nnp.ima-press.net/nnp/article/view/1132</self-uri><abstract><p>Headache is a common symptom in acute cerebrovascular diseases; however, no studies have evaluated the prevalence of specific headache types in patients with transient ischemic attacks (ТIАs).</p><sec><title>Objective</title><p>Objective: to analyze all headaches within the last year and the last week before and during ТIАs.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. TIA patients included in the study (female 55% (n=120); mean age, 56.1 years) according to the existing definition of TIAs had a transient neurological dysfunction episode caused by focal brain damage or retinal ischemia for up to 24 hours without forming a new acute heart attack on diffusion-weighted MRI (n=112) or CT (n=8). All the patients were examined by one neurologist within one day after their admission. Patients (female 64% (n=192); mean age, 58.7 years) who had been admitted with a diagnosis of lumbago, lumbar spine osteochondrosis, or gastrointestinal ulcer were examined as a control group. A clinical semistructured face-to-face interview with the patients of both groups was carried out to analyze headache.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The prevalence of migraine without aura during one year before TIA was substantially higher in patients with TIA than in control ones: 20.8 and 7.8%, respectively (p=0.002). Twenty-two (18.3%) patients had sentinel or warning headache within the last week before a TIA that manifested as an increase in and greater frequency of previous headache, as lack of effect of painkillers, and as the emergence of a new type of headaches, which were previously absent. During TIAs, 16 (13.3%) patients developed a new type of headache. Twelve of these 16 patients had migraine-like headache; three patients had headache resembling tension headache; one patient had a thunderclap headache. None of the control patients was found to have a new type of headache. TIAs were significantly more common in the vertebrobasilar basin than in the carotid artery one in patients with headache during the last week before and during TIA.</p></sec><sec><title>Conclusion</title><p>Conclusion. The one year prevalence of migraine was significantly higher in ТIА patients than in control patients, and so was the prevalence of headache within the last week before and during TIA. Migraine-like headache prevailed among the new types of headaches in the development of TIA. A previous headache with a change in characteristics and a new type of headache can be predictors for TIA. </p></sec></abstract><trans-abstract xml:lang="ru"><p>Головная боль является распространенным симптомом при цереброваскулярных заболеваниях, однако ни в одном исследовании не была оценена распространенность специфических видов головной боли у пациентов с транзиторными ишемическими атаками (ТИА).</p><p>Целью настоящего исследования было проанализировать все виды головной боли за последний год, за последнюю неделю до TИA и во время TИA.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Включенные в исследование пациенты с TИA (n=120; 55% женщин; средний возраст – 56,1 года) согласно существующему определению ТИА имели преходящий эпизод неврологической дисфункции, вызванный очаговым поражением головного мозга или ишемией сетчатки продолжительностью до 24 ч без формирования нового острого инфаркта на МРТ с диффузионно-взвешенными изображениями (n=112) или КТ (n=8). Все пациенты были обследованы в течение одного дня после поступления одним неврологом. В качестве контрольной группы были обследованы пациенты (n=192; 64% женщин; средний возраст – 58,7 года), поступившие с диагнозом «люмбаго», «остеохондроз поясничного отдела позвоночника» или «язва желудочно-кишечного тракта». С пациентами обеих групп проведено клиническое полуструктурированное интервью по типу «лицом к лицу» для анализа головной боли.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Распространенность мигрени без ауры в течение года до ТИА была значительно выше у пациентов с ТИА, чем в контрольной группе: 20,8 и 7,8% соответственно (р=0,002). Двадцать два пациента (18,3%) имели сторожевую, или предупреждающую, головную боль в течение последней недели перед ТИА, проявлявшейся усилением, учащением предыдущей головной боли, отсутствием эффекта от обезболивающих препаратов, а также возникновением нового типа головной боли, которого не было ранее. Во время ТИА у 16 (13,3%) пациентов возник новый тип головной боли. У 12 из этих 16 была мигренеподобная головная боль, у трех пациентов – головная боль, напоминающая головную боль напряжения, и у одного пациента – громоподобная головная боль. Ни у одного пациента контрольной группы не было нового типа головной боли. ТИА в вертебробазилярном бассейне встречались значительно чаще, чем в бассейне сонных артерий, у пациентов, имеющих головную боль в течение последней недели перед ТИА и во время ТИА.</p></sec><sec><title>Выводы</title><p>Выводы. Распространенность мигрени в течение года была значительно выше у пациентов с ТИА, чем в контроле, так же как и распространенность головной боли в течение последней недели перед ТИА и во время ТИА. Мигренеподобная головная боль превалировала среди новых типов головной боли при развитии ТИА. Предыдущая головная боль с изменением характеристик и новый тип головной боли могут быть предикторами ТИА. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>транзиторная ишемическая атака</kwd><kwd>вторичная головная боль</kwd><kwd>мигрень</kwd><kwd>мигренеподобная головная боль</kwd><kwd>сторожевая головная боль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>transient ischemic attack</kwd><kwd>secondary headache</kwd><kwd>migraine</kwd><kwd>migraine-like headache</kwd><kwd>sentinel headache</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Portenoy RK, Abissi CJ, Lipton RB, et al. Headache in cerebrovascular disease. Stroke. 1984;15(6):1009-12. doi: 10.1161/01.STR.15. 6.1009</mixed-citation><mixed-citation xml:lang="en">Portenoy RK, Abissi CJ, Lipton RB, et al. Headache in cerebrovascular disease. 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