nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2019-2-86-88nnp-1105Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯSchizophrenia-like disorder in Wilson's diseaseШизофреноподобное расстройство при болезни ВильсонаСпиринаИ. Д.SpirinaI. D.

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

ФаузиЕ. С.FawzyE. S.

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

ШевченкоЮ. Н.ShevchenkoYu. N.

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

ШорниковА. В.ShornikovA. V.

Андрей Владимирович Шорников

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Andrei Vladimirovich Shornikov

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

shornikov@ukr.netСмольяноваА. В.SmolianovaA. V.

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

НиколайчикА. Н.NikolaychikA. N.

Кафедра психиатрии, общей и медицинской психологии

Днепропетровск

Department of Psychiatry, General and Medical Psychology

Dnipropetrovsk

Государственное учреждение «Днепропетровская медицинская академия Министерства здравоохранения УкраиныУкраинаDnipropetrovsk Medical Academy, Health Ministry of UkraineUkraine2019160620191128688Copyright © Spirina I.D., Fawzy E.S., Shevchenko Y.N., Shornikov A.V., Smolianova A.V., Nikolaychik A.N., 20192019Спирина И.Д., Фаузи Е.С., Шевченко Ю.Н., Шорников А.В., Смольянова А.В., Николайчик А.Н.Spirina I.D., Fawzy E.S., Shevchenko Y.N., Shornikov A.V., Smolianova A.V., Nikolaychik A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1105

Wilson's (Wilson–Konovalov) disease (WD) is a chronic progressive disease resulting from impaired body copper metabolism with damages to target organs (liver, brain, and kidneys). The paper describes a clinical case of organic delusional (schizophrenia-like) disorder in a patient with WD. The characteristic feature of its psychiatric onset in the patient is schizophrenia-like disorders in the absence of neurological and gastroenterological symptoms. Because of this onset of WD, patients have not received specific treatment for a long time (frequently before the appearance of the Kayser–Fleischer rings or the occurrence of cirrhosis). Thus, the diagnostic search should include WD in young patients with a primary psychotic episode. The search for early effective methods for WD verification is of interest for further investigations.

Болезнь Вильсона (Вильсона–Коновалова, БВ) – хроническое прогрессирующее заболевание, возникающее вследствие нарушения обмена меди в организме с поражением органов мишеней (печень, головной мозг, почки). Представлено клиническое наблюдение органического бредового шизофреноподобного расстройства у пациента с БВ. Характерной особенностью психиатрической формы начала заболевания у пациента явились шизофреноподобные расстройства при отсутствии неврологической и гастроэнтерологической симптоматики. Из-за подобного дебюта БВ пациенты длительное время (зачастую до появления колец Кайзера–Флейшера или возникновения цирроза) не получают специфического лечения. Таким образом, в диагностический поиск при первичном психотическом эпизоде у молодых пациентов следует включать БВ. Поиск ранних эффективных методов верификации БВ представляет интерес для дальнейших исследований.

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The authors declare that there are no conflicts of interest present.