nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2019-2-60-64nnp-1101Research ArticleORIGINAL INVESTIGATIONSОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ И МЕТОДИКИEthnic characteristics of location for cerebral aneurysmsЭтнические особенности локализации аневризм сосудов головного мозгаЧугуноваС. А.ChugunovaS. A.

Саргылана Афанасьевна Чугунова

677000, Якутск, ул. Ойунского, 27 

Sargylana Afanasyevna Chugunova

27, Oiunsky St., Yakutsk 677000

sa.chugunova@mail.ruМедицинский институт ФГАОУ «Северо-Восточный федеральный университет им. М.К. Аммосова»РоссияMedical Institute, M.K. Ammosov North-Eastern Federal UniversityRussian Federation2019150620191126064Copyright © Chugunova S.A., 20192019Чугунова С.А.Chugunova S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1101Objective

Objective: to establish the characteristics of location for cerebral aneurysms according to ethnicity in the population of Yakutia.

Patients and methods

Patients and methods. A total of 433 patients with aneurysmal hemorrhagic stroke (AHS) who had been admitted consecutively to the regional vascular center (Yakutsk) were examined. Group 1 included representatives of the indigenous ethnic groups of the Asian race in Yakutia (n=331; 33.8% of men); Group 2 comprised patients of the Caucasian race (n=102; 45.1% of men). The diagnosis was made by digital subtraction cerebral angiography (77.6%) and multislice computed tomography angiography (22.4%).

Results

Results. A total of 433 ruptured saccular aneurysms, including the latter in the anterior cerebral and anterior communicating arteries (ACAAcoA) (33.8%), middle cerebral artery (MCA) (38.7%), internal carotid artery (ICA) (21.6%), and vertebrobasilar arteries (5.8%), were diagnosed. In Group 1, the most common location for aneurysms was MCA (41.1 and 39.7% in men and women, respectively); in Group 2, that was ACA-AcoA (52.2%) in men and ICA (42.8%) in women. The ethnic groups showed significant differences in the incidence of MCA aneurysms (40.2 and 26.4% in Groups 1 and 2; respectively (p=0.014)); (odds ratio (OR = 1.866; 95% confidence interval (CI), 1.111–3.146). In Group 1, the incidence of MCA aneurysms was higher in women than in those in Group 2 (p=0.012) (OR=2.417; 95% CI, 1.155–5.141).

Conclusion

Conclusion. The location for cerebral aneurysms differs according to ethnicity. In Yakutia among AHS patients, the most frequent location for aneurysms is MCA among indigenous Asians, while that is ACA-AcoA in Caucasian men and ICA is in Caucasian women. The incidence of MCA aneurysms is significantly higher in indigenous Asian women than in Caucasian ones.

Цель исследования – установить особенности локализации аневризм сосудов головного мозга в зависимости от этнической принадлежности в популяции Якутии.

Пациенты и методы

Пациенты и методы. Обследованы пациенты с аневризматическим геморрагическим инсультом – АГИ (n=433), последовательно госпитализированные в региональный сосудистый центр (Якутск). В 1-ю группу вошли представители коренных этносов азиатской расы Якутии (n=331; 33,8% мужчин); во 2-ю группу – пациенты европеоидной расы (n=102; 45,1% мужчин). Диагноз установлен по данным дигитальной субтракционной церебральной ангиографии (77,6%), мультиспиральной компьютерной томографической ангиографии (22,4%).

Результаты

Результаты. Всего диагностированы 433 мешотчатые аневризмы с разрывом, в том числе передней мозговой и передней соединительной артерий (ПМА-ПсоА) – 33,8%, средней мозговой артерии (СМА) – 38,7%, внутренней сонной артерии (ВСА) – 21,6%, артерий вертебробазилярного бассейна – 5,8%. Наиболее частой локализацией аневризм в 1-й группе у мужчин (41,1%) и женщин (39,7%) была СМА; во 2-й группе у мужчин – ПМА-ПсоА (52,2%), у женщин – ВСА (42,8%). Значимые различия в частоте аневризм между этническими группами установлены для СМА (40,2% в 1-й группе против 26,4% во 2-й; p=0,014; отношение шансов, OШ 1,866; 95% доверительный интервал, ДИ 1,111–3,146). Частота аневризм СМА у женщин в 1-й группе была выше, чем во 2-й (p=0,012; OШ 2,417; 95% ДИ 1,155–5,141).

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The authors declare that there are no conflicts of interest present.