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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2019-1-84-88</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-1051</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Anti-MOG syndrome: two case reports</article-title><trans-title-group xml:lang="ru"><trans-title>Синдром anti-MOG: описание двух случаев</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Сергеевич Котов</p><p>129110, Москва, ул. Щепкина, 61/2</p></bio><bio xml:lang="en"><p>Aleksey Sergeevich Kotov</p><p>61/2, Shchepkin St., Moscow 129110 </p></bio><email xlink:type="simple">alex-013@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirsky Moscow Regional Research Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>06</day><month>03</month><year>2019</year></pub-date><volume>11</volume><issue>1</issue><fpage>84</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kotov A.S., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Котов А.С.</copyright-holder><copyright-holder xml:lang="en">Kotov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/1051">https://nnp.ima-press.net/nnp/article/view/1051</self-uri><abstract><p>The paper describes two cases of adolescent-onset anti-MOG (myelin oligodendrocyte glycoprotein) syndrome. One case had an onset of optic neuritis, followed by myelitis; a recurrence of the syndrome occurred during interferon-β therapy. In the other case the syndrome also began with optic neuritis; and after a long latent period it was manifested as unilateral encephalitis with contralateral hemiparesis and rare epileptic seizures. Detection of anti-MOG syndrome is of great importance, because its management tactics is different from that for multiple sclerosis; furthermore, the laboratory diagnosis of this syndrome can be made in our country now.</p></abstract><trans-abstract xml:lang="ru"><p>Представлено два случая синдрома anti-MOG (myelin oligodendrocyte glycoprotein) с дебютом в подростковом возрасте. В первом случае у пациента заболевание дебютировало с оптического неврита с последующим присоединением миелита, на фоне лечения интерфероном бета произошел рецидив. Во втором случае у пациентки заболевание также началось с оптического неврита и после длительного латентного периода проявилось односторонним энцефалитом с контралатеральным гемипарезом и редкими эпилептическими приступами. Выявление синдрома anti-MOG имеет большое значение, потому что он требует иной, чем рассеянный склероз, тактики ведения пациентов, кроме того, в настоящее время в нашей стране возможна лабораторная диагностика этого синдрома.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>anti-MOG</kwd><kwd>оптический неврит</kwd><kwd>миелит</kwd><kwd>энцефалит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>anti-MOG syndrome</kwd><kwd>optic neuritis</kwd><kwd>myelitis</kwd><kwd>encephalitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kira J. Neuromyelitis optica and opticospinal multiple sclerosis: Mechanisms and pathogenesis. 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