nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2019-1-79-83nnp-1050Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯHashimoto's encephalopathy (a brief review of literature and a clinical case)Энцефалопатия Хашимото (краткий обзор литературы и клиническое наблюдение)КутлубаевМ. А.KutlubaevМ. A.

Мансур Амирович Кутлубаев

450005, Республика Башкортостан, Уфа, ул. Достоевского, 132, 

450008, Республика Башкортостан, Уфа, ул. Ленина, 3

Mansur Amirovich Kutlubaev

132, Dostoevsky St., Ufa 450005, Republic of Bashkortostan, 3, Lenin St., Ufa 450008, Republic of Bashkortostan

mansur.kutlubaev@yahoo.comГехтманО. В.GekhtmanO. V.ЗакироваЭ. Н.ZakirovaE. N.ГБУЗ Республики Башкортостан «Республиканская клиническая больница им. Г.Г. Куватова»; ГБОУ ВО «Башкирский государственный медицинский университет» Минздрава РоссииРоссияG.G. Kuvatov Republican Clinical Hospital; Bashkir State Medical University, Ministry of Health of RussiaRussian FederationГБУЗ Республики Башкортостан «Республиканская клиническая больница им. Г.Г. Куватова»РоссияG.G. Kuvatov Republican Clinical HospitalRussian Federation2019060320191117983Copyright © Kutlubaev М.A., Gekhtman O.V., Zakirova E.N., 20192019Кутлубаев М.А., Гехтман О.В., Закирова Э.Н.Kutlubaev М.A., Gekhtman O.V., Zakirova E.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/1050

Hashimoto's encephalopathy (HE) is a steroid-responsive encephalopathy associated with autoimmune thyroiditis; it is based on the inflammatory brain process associated with a cross-reaction to anti-thyroid autoantibodies. HE is manifested by impaired consciousness and focal neurological symptoms. The determination of the serum and cerebrospinal fluid levels of antithyroid autoantibodies plays a main role in diagnosing HE. The latter is treated with glucocorticoids and other immunosuppressive agents. The prognosis is favorable providing that the treatment of the disease is initiated in time.

Энцефалопатия Хашимото (ЭХ) – стероид-реактивная энцефалопатия, ассоциированная с аутоиммунным тиреоидитом, в ее основе лежит воспалительный процесс в головном мозге, связанный с перекрестной реакцией на аутоантитела к щитовидной железе. ЭХ проявляется нарушением сознания и очаговой неврологической симптоматикой. В диагностике ЭХ основная роль принадлежит определению уровня антитиреоидных аутоантител в сыворотке крови и цереброспинальной жидкости. Лечение заболевания проводится глюкокортикоидами и другими иммуносупрессивными средствами. В случае своевременного лечения прогноз благоприятный.

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The authors declare that there are no conflicts of interest present.